18 Questions
What is the primary effect of atropine on the detrusor muscle?
Decreases its tone
Which drug is known for causing prolongation of QT interval at high doses among the listed antimuscarinic drugs?
Solifenacin
Which antimuscarinic drug has the greatest M3 selectivity among the listed options?
Darifenacin
What is a common side effect of anticholinergic drugs that may affect vision?
Blurred vision
Which drug, used for motion sickness, is classified as a muscarinic antagonist?
Scopolamine
Why should anticholinergic drugs be used with caution in pregnant females according to the text?
They decrease milk production
Which receptor subtype is located in all autonomic nervous system ganglia and the adrenal medulla?
Nicotinic n
Where are Nicotinic m receptors primarily located?
Neuromuscular junction
Which subtype of cholinergic receptor is primarily located in the bladder detrusor and GI smooth muscle?
M3
Beta 2 adrenergic receptors cause which of the following effects?
Bronchial dilation
Which drug is used for dry mouth treatment in Sjogren Syndrome by activating muscarinic receptors?
Cevimeline
What do muscarinic antagonists selectively block the effects of at muscarinic receptors?
Acetylcholine
Which receptor activation leads to vasoconstriction and mydriasis?
Alpha 1
What is the therapeutic use of alpha 2 blockade?
Relief of severe pain
Which condition is treated with alpha 1 blockade?
Hypertension
What are the adverse effects of beta 2 blockade?
Bronchoconstriction
In which condition does beta 1 activation enhance impulse conduction in the AV node?
Cardiac arrest
What is the main therapeutic application of beta blockade?
Hypertension
Test your knowledge on different types of receptors and their normal responses to activation and blockade (agonist vs antagonist). Learn about the locations and functions of Nicotinic n, Nicotinic m, Muscarinic, M1, M2, and M3 receptors in the body.
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