Managing T2DM with GLP-1 RAs for Heart Failure

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9 Questions

What is the recommended anticoagulation therapy for patients with T2DM and LVEF >40% (HFmrEF)?

Prolonged triple therapy with low-dose ASA, clopidogrel, and an OAC for up to 3 months

What is the recommended diagnostic work-up for patients with diabetes and aortic aneurysm?

The same diagnostic work-up as in patients without diabetes

What is the recommended glucose-lowering medication for patients with T2DM?

Medications with proven cardiovascular benefit should be used

What is the recommended screening for atrial fibrillation in patients with diabetes?

Opportunistic screening for atrial fibrillation by pulse taking or ECG is recommended in patients with diabetes aged 60 years or older

What is the recommended use of low-dose aspirin (ASA) in patients with diabetes and chronic kidney disease (CKD)?

Low-dose ASA (75-100 mg o.d.) is recommended in patients with CKD and ASCVD

Which of the following is the recommended target for urinary albumin-to-creatinine ratio (UACR) in patients with T1DM to reduce cardiovascular events and kidney failure?

UACR 3 mg/mmol (30 mg/g)

What is the recommended diagnostic work-up for patients with suspected heart failure?

Diagnostic tests are recommended in all patients with suspected heart failure

What is the recommended glucose-lowering therapy for patients with T1DM and cardiovascular disease?

Insulin therapy should be the mainstay of treatment for these patients

What is the recommended approach to management of patients with T2DM and heart failure with mildly reduced ejection fraction (HFmrEF)?

Prolonged triple therapy with low-dose ASA, clopidogrel, and an OAC for up to 3 months may be considered if the thrombotic risk outweighs the bleeding risk

Learn about the multifactorial approach to managing Type 2 Diabetes Mellitus (T2DM) by focusing on GLP-1 Receptor Agonists (RAs) like lixisenatide, liraglutide, semaglutide, exenatide ER, and dulaglutide in relation to heart failure risk. Explore their impact on HF hospitalization and their role in glucose-lowering and diabetes treatment.

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