Managing T2DM with GLP-1 RAs for Heart Failure
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Questions and Answers

What is the recommended anticoagulation therapy for patients with T2DM and LVEF >40% (HFmrEF)?

  • Anticoagulation therapy is not recommended due to the bleeding risk outweighing the thrombotic risk
  • Prolonged triple therapy with low-dose ASA, clopidogrel, and an OAC for up to 3 months (correct)
  • No anticoagulation therapy is recommended
  • Esomeprazole for gastric protection

What is the recommended diagnostic work-up for patients with diabetes and aortic aneurysm?

  • A more extensive diagnostic work-up compared to patients without diabetes
  • No specific diagnostic work-up is recommended for these patients
  • Diagnostic work-up should focus only on the aortic aneurysm and not consider the patient's diabetes
  • The same diagnostic work-up as in patients without diabetes (correct)

What is the recommended glucose-lowering medication for patients with T2DM?

  • No specific recommendations are made for glucose-lowering medications in patients with T2DM
  • Metformin should be the first-line medication regardless of cardiovascular benefit
  • Insulin should be the preferred glucose-lowering medication for all patients with T2DM
  • Medications with proven cardiovascular benefit should be used (correct)

What is the recommended screening for atrial fibrillation in patients with diabetes?

<p>Opportunistic screening for atrial fibrillation by pulse taking or ECG is recommended in patients with diabetes aged 60 years or older (B)</p> Signup and view all the answers

What is the recommended use of low-dose aspirin (ASA) in patients with diabetes and chronic kidney disease (CKD)?

<p>Low-dose ASA (75-100 mg o.d.) is recommended in patients with CKD and ASCVD (B)</p> Signup and view all the answers

Which of the following is the recommended target for urinary albumin-to-creatinine ratio (UACR) in patients with T1DM to reduce cardiovascular events and kidney failure?

<p>UACR 3 mg/mmol (30 mg/g) (B)</p> Signup and view all the answers

What is the recommended diagnostic work-up for patients with suspected heart failure?

<p>Diagnostic tests are recommended in all patients with suspected heart failure (C)</p> Signup and view all the answers

What is the recommended glucose-lowering therapy for patients with T1DM and cardiovascular disease?

<p>Insulin therapy should be the mainstay of treatment for these patients (C)</p> Signup and view all the answers

What is the recommended approach to management of patients with T2DM and heart failure with mildly reduced ejection fraction (HFmrEF)?

<p>Prolonged triple therapy with low-dose ASA, clopidogrel, and an OAC for up to 3 months may be considered if the thrombotic risk outweighs the bleeding risk (B)</p> Signup and view all the answers

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