Reactive Species and Redox Equilibrium Quiz

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Questions and Answers

What is the principal source of defensive pro-oxidants generated in the respiratory burst of neutrophils?

  • Nitric oxide synthases (NOS)
  • Xanthine oxidase (XO)
  • NADPH oxidase (NOX)
  • Reactive species (correct)

Which of the following is NOT a potential cause of oxidative stress?

  • Biochemical processes leading to the production of reactive species
  • Limited capabilities of endogenous antioxidant systems
  • Exposure to damaging agents like environmental pollutants
  • Consumption of antioxidant-rich foods (correct)

What plays a vital role in preserving the correct functionality of cellular vital functions?

  • Oxidative damage
  • Redox equilibrium (correct)
  • Reactive species
  • Antioxidants

Oxidative stress can lead to damage in which of the following cellular biomolecules?

<p>Polynucleotides (A)</p> Signup and view all the answers

Which enzyme is enzymatically responsible for the production of reactive species?

<p>Xanthine oxidase (XO) (C)</p> Signup and view all the answers

What are reactive oxygen and nitrogen species (ROS/RNS) known to damage under oxidative stress?

<p>Proteins and sugars (C)</p> Signup and view all the answers

What are some examples of enzymatic scavengers of reactive oxygen species (ROS) mentioned in the text?

<p>Superoxide dismutase (SOD) and glutathione peroxidase (GPX) (C)</p> Signup and view all the answers

How is oxidative damage typically assessed according to the text?

<p>Measurement of secondary oxidation products (B)</p> Signup and view all the answers

Why are clinical studies required to include multiple biomarkers when assessing antioxidant status and oxidative stress?

<p>To adequately assess in vivo antioxidant status/oxidative stress (B)</p> Signup and view all the answers

Which type of biomarkers are mentioned as indicators of radical-induced damage in biological tissues and fluids?

<p>Secondary oxidation products (C)</p> Signup and view all the answers

Why are antioxidant enzymes considered important according to the text?

<p>To cope with oxidative stress caused by metabolism and environmental factors (D)</p> Signup and view all the answers

What is the main cause of oxidative stress in the human body?

<p>Reactive oxygen species (B)</p> Signup and view all the answers

Which system in the human body regulates the levels of free radicals to maintain physiological balance?

<p>Antioxidant system (A)</p> Signup and view all the answers

What is the consequence of excessive free radicals under conditions of oxidative stress?

<p>Oxidative damage to proteins, lipids, and nucleic acids (D)</p> Signup and view all the answers

Which organelle is identified as the primary source of reactive oxygen species in all cell types?

<p>Mitochondria (C)</p> Signup and view all the answers

How can hydrogen peroxide (H2O2) generate the highly reactive hydroxyl radical (HO ) in the presence of certain ions?

<p>Fenton reaction (D)</p> Signup and view all the answers

What is a potential application of biomarkers of oxidative stress in humans?

<p>Assessment of disease status (D)</p> Signup and view all the answers

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