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Questions and Answers
What is a key benefit of using megavoltage electron beams in radiotherapy?
What is a key benefit of using megavoltage electron beams in radiotherapy?
Which component is not part of the electron mode setup in radiotherapy?
Which component is not part of the electron mode setup in radiotherapy?
What characteristic of electron beam dose distribution is notable when comparing it to photon beams?
What characteristic of electron beam dose distribution is notable when comparing it to photon beams?
What is referred to as the depth of dose maximum for electron beams?
What is referred to as the depth of dose maximum for electron beams?
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Why is the insert placed close to the skin in electron beam therapy?
Why is the insert placed close to the skin in electron beam therapy?
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Which of the following is a typical energy range for modern electron beam therapy?
Which of the following is a typical energy range for modern electron beam therapy?
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What common misconception might a student have about the surface dose of electron beams?
What common misconception might a student have about the surface dose of electron beams?
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What does the general shape of the central axis depth dose curve indicate for electron beams?
What does the general shape of the central axis depth dose curve indicate for electron beams?
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What parameter is essential to measure for each clinical electron beam energy?
What parameter is essential to measure for each clinical electron beam energy?
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What does Rp represent in dosimetric parameters for electron beams?
What does Rp represent in dosimetric parameters for electron beams?
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Which electron beam energy has the highest surface dose percentage according to the dosimetric parameters?
Which electron beam energy has the highest surface dose percentage according to the dosimetric parameters?
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To shield the skin surface from a 9 MeV electron beam, what thickness of bolus material is calculated?
To shield the skin surface from a 9 MeV electron beam, what thickness of bolus material is calculated?
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Which device is NOT typically used to measure PDDs of electron beams?
Which device is NOT typically used to measure PDDs of electron beams?
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Why is lead preferred over tungsten for shielding in electron beam applications?
Why is lead preferred over tungsten for shielding in electron beam applications?
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Which of the following factors influences the PDDs for electron beams?
Which of the following factors influences the PDDs for electron beams?
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For a 6 MeV electron beam, what is the measured R50 value?
For a 6 MeV electron beam, what is the measured R50 value?
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What is the primary mechanism through which electrons lose kinetic energy in an absorber?
What is the primary mechanism through which electrons lose kinetic energy in an absorber?
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What is the mass stopping power composed of?
What is the mass stopping power composed of?
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How much energy do high energy electrons lose in water?
How much energy do high energy electrons lose in water?
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What does the term 'virtual source position' refer to in electron beam therapy?
What does the term 'virtual source position' refer to in electron beam therapy?
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What is the effective source-surface distance (SSDeff)?
What is the effective source-surface distance (SSDeff)?
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How can the inverse square law be applied in electron beam therapy?
How can the inverse square law be applied in electron beam therapy?
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Why is the nominal SSD typically a fixed distance from the distal edge of the electron cone?
Why is the nominal SSD typically a fixed distance from the distal edge of the electron cone?
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What relationship does SSDeff have with changes in depth of measurement?
What relationship does SSDeff have with changes in depth of measurement?
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When normalizing beam profile data in a phantom, which normalization method refers to the values off the central axis?
When normalizing beam profile data in a phantom, which normalization method refers to the values off the central axis?
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According to the IEC specifications, what is the maximum excess dosage allowable within the 90% isodose contour?
According to the IEC specifications, what is the maximum excess dosage allowable within the 90% isodose contour?
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What is the maximum allowed distance between the 90% dose level and the geometrical beam edge along diagonals?
What is the maximum allowed distance between the 90% dose level and the geometrical beam edge along diagonals?
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What percentage difference is allowed in the cross-beam profile measured at depth zmax for symmetric points?
What percentage difference is allowed in the cross-beam profile measured at depth zmax for symmetric points?
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In electron beam therapy, which is typically the depth at which the dose is prescribed?
In electron beam therapy, which is typically the depth at which the dose is prescribed?
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What is the typical SSD used for delivering electron beam therapy?
What is the typical SSD used for delivering electron beam therapy?
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Which of the following is NOT a usual prescribed depth for treatment in electron beam therapy?
Which of the following is NOT a usual prescribed depth for treatment in electron beam therapy?
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The IEC specification for beam flatness of electron beams is particularly concerned with measurements taken at which point?
The IEC specification for beam flatness of electron beams is particularly concerned with measurements taken at which point?
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What does R80 or R90 signify in treatment dose specifications?
What does R80 or R90 signify in treatment dose specifications?
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Why is it important to report the maximum dose in electron beam treatments?
Why is it important to report the maximum dose in electron beam treatments?
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What are isodose curves used to represent?
What are isodose curves used to represent?
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What primary factor affects the spread of isodose curves in electron beam treatments?
What primary factor affects the spread of isodose curves in electron beam treatments?
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At what point is the reference dose typically measured for isodose curves?
At what point is the reference dose typically measured for isodose curves?
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What is a notable characteristic of electron beam isodose curves?
What is a notable characteristic of electron beam isodose curves?
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What happens to an electron beam as it penetrates an absorber?
What happens to an electron beam as it penetrates an absorber?
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What factors influence the curves of isodose distributions in electron beam therapies?
What factors influence the curves of isodose distributions in electron beam therapies?
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What is the significance of the obliquity effect in electron beams?
What is the significance of the obliquity effect in electron beams?
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What is the relationship between the depth of the 90% dose level (R90) and kinetic energy (EK)?
What is the relationship between the depth of the 90% dose level (R90) and kinetic energy (EK)?
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How is the output factor for electron beams defined?
How is the output factor for electron beams defined?
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At what condition is the obliquity factor of 1.00 observed?
At what condition is the obliquity factor of 1.00 observed?
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What does the depth dose profile represent?
What does the depth dose profile represent?
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Which of the following statements about R80 is true?
Which of the following statements about R80 is true?
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What does the term 'therapeutic range' refer to in electron beam therapy?
What does the term 'therapeutic range' refer to in electron beam therapy?
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What effect does obliquity have on the depth dose of electron beams?
What effect does obliquity have on the depth dose of electron beams?
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Study Notes
Electron Beam Dosimetry
- Megavoltage electron beams are a significant treatment modality in modern radiotherapy, particularly for superficial tumors.
- Electrons have been utilized in radiotherapy since the early 1950s.
- Modern linear accelerators (linacs) produce several electron beam energies ranging from 4 MeV to 25 MeV, in addition to photon energies.
- In electron mode, the x-ray target is removed, scattering foils are placed, and an applicator is used to restrict electron leakage outside the treatment field.
- Electron beams are collimated by an applicator (e.g., cone) and cutout (insert). Collimation is energy-dependent and uses thin, low atomic number materials (avoiding bremsstrahlung production).
- The insert is placed close to the skin to minimize the large spot size associated with geometric spread.
- The general shape of the depth dose curve for electron beams differs from that of photon beams, exhibiting a more rapid falloff.
- Electron beam central axis percentage depth dose curves display uniform dose with a rapid falloff.
- Surface dose is high (typically 80-100%).
- Maximum dose occurs at a specific depth (depth of dose maximum, Zmax).
- Beyond Zmax, the dose drops off rapidly to a low level; this low-level dose is the bremsstrahlung tail. This tail is a small percentage of the maximum dose.
- Electron beams are nearly monoenergetic as they leave the linac accelerating waveguide.
- Interactions within the body include interactions through the waveguide exit window, scattering foils, transmission ionization chambers, and air. Bremsstrahlung radiation is produced during these interactions and forms a tail on the PDD curve.
- Interactions with the absorbing medium involve elastic and inelastic Coulomb force interactions between the incident electrons and the atoms of the medium.
- Inelastic collisions lead to energy loss through ionization and excitation of absorber atoms. These collisions can be hard or soft.
- Hard collisions result in the ejection of orbital electrons with sufficient energy to ionize other atoms; these ejected electrons are called delta rays.
- Soft collisions result in the ejection of orbital electrons with insufficient energy to ionize other atoms.
- Elastic collisions primarily change the direction of motion of the incident electron (elastic scattering), causing a small energy loss.
- The cumulative effect of multiple scattering events causes the incident electron to lose kinetic energy.
- The rate of energy loss per gram and per square centimeter is mass stopping power, comprised of mass collision stopping power and mass radiation stopping power.
- High-energy electrons lose energy at a rate of 2 MeV/cm in water.
- Depth of penetration is approximately 0.5 cm/MeV.
- In contrast to photon beams, electron beams do not have a fixed focal point. Rather, they appear to originate from a virtual source.
- Effective source-surface distance (SSDeff) is measured from the virtual source to the edge of the cone applicator.
- The inverse square law can be used to correct for small differences (air gaps) between the actual patient and the nominal SSD.
- Data, normalized to the applicator (cone) edge, is used to determine SSDeff. A typical example is a graph versus air gap g, with a slope reflecting the effective SSD formula.
- The nominal SSD is usually a fixed distance from the distal edge of the cone and coincides with the linac isocenter, for practical reasons.
- Effective SSD is determined from measurements at Zmax in a phantom. The value does not change with depth of measurement.
- Measures of effective SSD depends on the energy of electron beams, and must be measured for every electron beam energy used in the clinic.
- Key dosimetric parameters include R90 (90% depth dose), R80 (80% depth dose), R50 (50% depth dose), Rp (practical range), E/4, E/2, and surface dose.
- Typical electron beam energies frequently used, with their corresponding values for depth-dose parameters, are identified.
- Shielding can be calculated using Rp, and thicknesses of various materials are presented for different scenarios.
Howe Work
- Questions about the best thickness of Tungsten shield for eye shielding from 6 MeV electrons are asked.
- Also inquired regarding the preferential use of Lead over Tungsten.
Clinical Considerations
- Electron beam therapy is often used for superficial or subcutaneous diseases.
- Treatment is usually with a single, directly positioned field at a 100 cm nominal SSD.
- Dose is typically prescribed at the depth (that lies at, or beyond, the target distal margin): Zmax, R90, or R80
- Healthy tissue sparing is maximized by prescribing the dose at these depths
- The maximum dose within the target may be 20% higher than the prescribed dose, and therefore should be reported.
Isodose Distributions
- Isodose curves connect points of equal dose, within the medium. Curves are usually drawn at dose intervals.
- Isodose curves give the distribution in the medium, at a given dose.
- Isodose curves often show how the dose changes due to a variety of factors (energy, field size, beam collimation).
Electron MU Calculation
- Dose depends on time, field size, depth, and distance.
- A formula exists for Electron MU calculation (MU = Dose/(D' × OF × COF × IDL × PDD × ISL)), incorporating several factors like dose, cutout factor, field-size correction, distance correction, and isodose line.
- The prescribed dose is typically 90% or 80% of the dose at Dmax.
- If calibration is performed at dref, (which is usually estimated as 0.6R50 – 0.1), then, MU can be calculated.
Electron Beam Flatness and Symmetry
- IEC standards specify measurements of beam flatness (and symmetry) at Zmax.
- Distances between the 90% dose level and the geometrical beam edge are measured, using major and minor axes.
- A maximum dose value within the 90% isodose contour should not exceed 1.05 times the central-axis dose at the same depth.
- Cross-beam profile symmetry is measured and cannot deviate more than 3% for symmetric points with respect to the central ray.
Dosimetric Parameters of Electron Beams
- Electron beams (unlike photons) show an increase in percentage surface dose with increasing beam energy.
- Zmax does not follow a clear trend with electron beam energies.
- Depth dose curves are measured at specific reference distances (SSD).
- The output factor is defined as the ratio of the dose at the field size, to reference field size. Ratio is calculated at Zmax, at a nominal 100 cm SSD.
- Beam obliquity (a) is defined by the angle between the beam axis and the normal to the phantom. PDD measurements for oblique incidences deviate from normal incidences at high angles.
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Description
Test your knowledge on the use of megavoltage electron beams in radiotherapy. This quiz includes questions about electron beam dose distribution, setup components, and dosimetric parameters. Sharpen your understanding of the intricacies involved in electron beam therapy.