Radiotherapy Principles and Dosage Quiz

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Questions and Answers

What is the purpose of using 3D CT scanning in conformal RT?

  • To deliver less dose to healthy cells
  • To deliver a high precise immobilization
  • To induce calreticulin to the surface of cancer cells
  • To circle the tumor and plan for treatment (correct)

What is the main goal of intensity modulated RT (IMRT)?

  • To deliver less dose to healthy cells (correct)
  • To induce calreticulin to the surface of cancer cells
  • To circle the tumor and plan for treatment
  • To deliver a high precise immobilization

Which process determines the effectiveness of the anti-tumor response and the release of CD8 cytotoxic T-cells?

  • Tumor-derived DNA inducing DNA pathway sensing (correct)
  • Inducing calreticulin to the surface of cancer cells
  • Delivery of a high precise immobilization
  • Inhibiting TGFbeta and CSF-1

Why does RT PLUS ANTI-CTL4 not respond well?

<p>It counteracts with stop signals by inhibiting TGFbeta and CSF-1 (A)</p> Signup and view all the answers

What is required for stereotactic RT to deliver the dose accurately?

<p>Delivery of a high precise immobilization (A)</p> Signup and view all the answers

What effect does RT PLUS IO have according to mouse models?

<p>It improves tumor control and induces abscopal effect (D)</p> Signup and view all the answers

What is the main purpose of radiotherapy?

<p>To deliver high energy X-rays to treat malignant tumors (B)</p> Signup and view all the answers

How is radiation dose measured in radiotherapy?

<p>In Grays (Gy) (C)</p> Signup and view all the answers

What is the recommended radiation dose to kill tumor cells?

<p>40-60 Gy (B)</p> Signup and view all the answers

Which type of imaging is a step in the radiotherapy treatment process?

<p>Computed Tomography (CT) imaging (B)</p> Signup and view all the answers

What technology does a linear accelerator use in radiotherapy?

<p>Microwave technology (B)</p> Signup and view all the answers

How are the X-rays shaped in radiotherapy to match the tumor's shape?

<p>By using a collimator (A)</p> Signup and view all the answers

What is the main function of a linear accelerator in radiotherapy?

<p>To emit high energy X-rays (C)</p> Signup and view all the answers

Which technique is used to deliver radiation at the appropriate dosage and minimize side effects in radiotherapy?

<p>Intensity modulated radiotherapy (D)</p> Signup and view all the answers

What is the recommended radiation dose needed to kill tumor cells in radiotherapy?

<p>40-60 Gy (D)</p> Signup and view all the answers

What is the purpose of imaging in the steps of radiotherapy treatment?

<p>To plan the treatment (D)</p> Signup and view all the answers

What technology is used to shape X-rays to match the tumor's shape in radiotherapy?

<p>Multileaf collimator (B)</p> Signup and view all the answers

How is radiation dose measured in radiotherapy?

<p>In Grays (Gy) (D)</p> Signup and view all the answers

What is the purpose of using intensity modulated RT (IMRT)?

<p>To minimize radiation dose to healthy cells and avoid parotids to reduce dry mouth (D)</p> Signup and view all the answers

How does radiotherapy induce antigen presenting to T cells?

<p>By inducing calreticulin to the surface of cancer cells and releasing HMGB-1 and ATP (B)</p> Signup and view all the answers

What determines the effectiveness of the anti-tumor response and the release of CD8 cytotoxic T-cells?

<p>The combination of RT PLUS ANTI-CTL4 (A)</p> Signup and view all the answers

What is required for stereotactic RT to deliver the dose accurately?

<p>High precise immobilization and many narrow beams converging at one target (B)</p> Signup and view all the answers

What effect does RT PLUS IO have according to mouse models?

<p>It improves tumor control and induces abscopal effect in mouse models (C)</p> Signup and view all the answers

What is the main purpose of using 3D CT scanning in conformal RT?

<p>To minimize tumor movement during treatment (B)</p> Signup and view all the answers

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Study Notes

Radiotherapy

  • The main purpose of radiotherapy is to kill tumor cells.

3D CT Scanning in Conformal RT

  • The purpose of using 3D CT scanning in conformal RT is to accurately locate and define tumor targets.
  • 3D CT scanning helps in identifying the tumor's shape and size.

Intensity Modulated RT (IMRT)

  • The main goal of IMRT is to deliver a high dose of radiation to the tumor while minimizing the dose to surrounding normal tissues.
  • IMRT is used to deliver radiation at the appropriate dosage and minimize side effects.

Radiation Dose Measurement

  • Radiation dose is measured in units of Gray (Gy).
  • The recommended radiation dose to kill tumor cells is typically in the range of 60-80 Gy.

Radiotherapy Treatment Process

  • Imaging is a crucial step in the radiotherapy treatment process, used to localize the tumor.
  • Linear accelerators use electromagnetic waves to produce high-energy X-rays.
  • X-rays are shaped to match the tumor's shape using a multileaf collimator.
  • The main function of a linear accelerator is to produce high-energy X-rays for radiotherapy.

Stereotactic RT

  • Accurate tumor localization and immobilization are required for stereotactic RT to deliver the dose accurately.

RT PLUS ANTI-CTL4

  • RT PLUS ANTI-CTL4 does not respond well due to the lack of CD8 cytotoxic T-cells.

Immune Response

  • The effectiveness of the anti-tumor response and the release of CD8 cytotoxic T-cells are determined by the process of antigen presenting to T cells.
  • Radiotherapy induces antigen presenting to T cells, releasing CD8 cytotoxic T-cells.

RT PLUS IO

  • According to mouse models, RT PLUS IO has a synergistic effect, enhancing the anti-tumor response.

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