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Questions and Answers
What is the mean lethal dose, the quantity of dose that delivers one inactivating event per cell?
What is the mean lethal dose, the quantity of dose that delivers one inactivating event per cell?
- D0 (correct)
- α
- β
- S
Which phase of interphase involves the duplication of DNA where 4 chromatids are joined at the centromere?
Which phase of interphase involves the duplication of DNA where 4 chromatids are joined at the centromere?
- Mitosis
- S (correct)
- G2
- G1
What is the significance of early responders having a higher α/β ratio?
What is the significance of early responders having a higher α/β ratio?
- Beta dominates at lower doses
- Alpha and beta components are irrelevant
- Alpha and beta components are equal
- Alpha outweighs beta at lower doses (correct)
Which type of aberration occurs when radiation damage happens after DNA replication, affecting only one daughter cell at the next division?
Which type of aberration occurs when radiation damage happens after DNA replication, affecting only one daughter cell at the next division?
Where are the genes housed in a linear sequence, and if in the wrong order, can change their function?
Where are the genes housed in a linear sequence, and if in the wrong order, can change their function?
What is the main consideration in determining the treatment plan using the Linear Quadratic model?
What is the main consideration in determining the treatment plan using the Linear Quadratic model?
Which component of the Linear Quadratic model is determined by the beta value?
Which component of the Linear Quadratic model is determined by the beta value?
What is a limitation of the linear curve in the Linear Quadratic model?
What is a limitation of the linear curve in the Linear Quadratic model?
What do smaller alpha/beta ratios (small alpha component, beta has more influence on lower dose) primarily affect?
What do smaller alpha/beta ratios (small alpha component, beta has more influence on lower dose) primarily affect?
What characteristic indicates a very high Linear Energy Transfer (LET) in the Linear Quadratic model?
What characteristic indicates a very high Linear Energy Transfer (LET) in the Linear Quadratic model?
Which type of scatter involves high-energy scatter with reduced energy, but still free to interact?
Which type of scatter involves high-energy scatter with reduced energy, but still free to interact?
What is the main effect of radiation interaction in the cell?
What is the main effect of radiation interaction in the cell?
What is the result of translocation as an aberration due to radiation exposure?
What is the result of translocation as an aberration due to radiation exposure?
What is the characteristic of indirect ionizing radiation?
What is the characteristic of indirect ionizing radiation?
What is the main purpose of dose estimation using lymphocyte aberrations?
What is the main purpose of dose estimation using lymphocyte aberrations?
What characteristic affects the shape of the cell survival curve in the context of linear energy transfer (LET)?
What characteristic affects the shape of the cell survival curve in the context of linear energy transfer (LET)?
What does the ALARA principle aim to balance in the context of radiation exposure?
What does the ALARA principle aim to balance in the context of radiation exposure?
What is the significance of the plating efficiency in the context of estimating cell survival?
What is the significance of the plating efficiency in the context of estimating cell survival?
What is the primary assumption of the multi-target multi-hit model for cell death?
What is the primary assumption of the multi-target multi-hit model for cell death?
Which characteristic determines how radiosensitive a cell is in the context of radiotherapy?
Which characteristic determines how radiosensitive a cell is in the context of radiotherapy?
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