Unit 2

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51 Questions

Elastic arteries aka conducting arteries , assist with propulsion through circulatory system because they have more elasticity!

True

Muscular arteries aka distributing arteries have a thick tunica media and LIE PROXIMAL

False

Match

Muscular arteries = Distributing (distal to elastic arteries) Elastic arteries = Conducting (largest : aorta and major branches) Arterioles = Smallest arteries Vasa vasorum = Capillaries that feed arteries

How does the Sympathetic NS direct blood flow from stomach to muscles

Through the process of messaging, receptors are instructed to make vascular shunt metarterioles to thoroughfare channel, while pre capillary sphincters close.

Positive Function of circle of willis

Should you get a clot on one location, blood can bypass to brain via other direction

Function of hepatic portal vein

Liver gets first pass of all nutrients and toxins absorbed ( arteries first capillary bed of digestive system)stomach capillaries go a to hepatic portal vein to secondary capillary bed at liver sinusoid , hepatocytes work remove waste and nutrients.

3 branches of aorta

Branchiocephalic trunk Left common carotid Left subclavian arteries

What vein divides two sections of brain?

Superior sagital sinus

When you see common, what is that indicative of?

Internal and external arteries or veins

Take a break, identify locations of Median cubical, basilic, cepahlic and brachial veins of arm

Good job

External iliac veins turns into

Femoral and great saphenous veins

Explain the relationship between flow pressure

Blood flow is directly proportional to blood pressure differences

3 resistance factors

Viscosity-(hematocrit &plasma) Length-blood vessels (longer =more resistance) Radius- wider vessel, lower resistance

(Resistance is inversely proportional to radius) Resistance = viscosity x length / radius

If the radius is doubled the new resistance is ____

1/16 the original, the inverse is true as well If radius is halved , new resistance is 16 times the original

Flow and velocity are directly proportional to?

Diameter (think traffic, more lanes =less traffic)

Match

Arteries = Thicker walls Veins = Larger lumens Arteries = Narrow lumens Veins = Have valves

Capillaries composed only of basal lamina and endothelium

True

Explain difference and physiological differences of arteries and veins

Arteries have thicker walls to withstand pressure Arteries are more elastic to expand and recoil and propel blood moving forward Veins have larger lumens to reduce resistance Veins have thinner walls to allow compliance (stretching) Veins have one way valves to ensure blood moves to heart.

Arteries have tunica media (smooth muscle) To do constricting and dialating

True

Greatest drop in pressure occurs in arterioles

True

______ peak pressure exerted by ejected blood against walls during cardiac systole

_______ is the minimum pressure in the arteries when blood is draining off into vessels downstream

Lapaces law

Force acting on the blood vessel is proportional to the diameter of the vessel, times blood pressure

Explain how to take bp

Cuff is inflated passed the point where sounds can be heard. Slowly deflated until systolic bp can be measured through audible sound returning, when the last sound is heard this is the diastolic pressure . We are hearing the sound of the pressure exerted on the brachial artery… not heart

MAP = diastolic pressure + ⅓ pulse pressure pulse pressure= Systolic - Diastolic if your patient has 160 mmHg systolic & 100 mmHg diastolic, what is their MAP?

120 mmHg

what two forms of veins assist with venous function?

Large lumens= little resistance valves = prevent backflow.

Venous system has Large compliance and acts as a blood reservoir about______ is in veins

what are 2 pumps aiding venous return

skeletal muscle contractions , respiratory pump

during diffusion at capillary beds ______ is to big to leave

palsma proteins

water moves from low concentration to high concentration. With regard to capillaries what is this called?

colloid osmotic pressure

regulation of blood flow

intrinsic = auto regulation, flow proportional to need. extrinsic = nervous and hormonal hormonal control = sympathetic stimulation of adrenal medullla to release EPI/NOREPI Nervous system = route blood flow and maintain pressure

Mediators of vasoconstriction and vasodilation

endothelin-I = vasoconstrict cold = vasoconstrict adenosine = Vasodilation Nictric Oxide (NO) = Vasodilation

Is it true? Myogenic control mechanism: ^ pressure= ^ stretch= Vasoconstriction v Pressure= v stretch = Vasodilation

True

Baroreceptor reflex control

  1. Baroreceptors in carotid aortic bodies detect changes in BP.
  2. Impulses are conducted to cardio regulatory and vasomotor control centers in medulla oblongata via Glossopharyngeal (IX) and Vagus (X) Nerves
  3. ^ BP will cause parasympathetic stimulation of heart, which decrease HR
  4. ^ BP will cause decrease sympathetic stimulation of hear, which decreases HR.
  5. ^ BP will cause vasomotor center to decrease sympathetic stimulation to BV, causing vasodilation. in short what Fbl does this represent (NFbl or PFbl) what is being adjusted and why?

Negative feedback, adjusting HR, SV and vasoconstriction allows correction of hyper- or hypotension

what post ganglionic neuro transmitter in sympathic NS is released , what is it?

Norepi.

what receptor of the sympathetic system is on the heart that binds to NorEPI?

Beta 1 NR

What Neurotransmitter at the post sympathetic ganlion release? what does it bind to?

Acetylcholine slows the heart rate by activating the M2 muscarinic receptor (M2R) that, in turn, opens the acetylcholine-activated potassium channel (IK,ACh) to slow the firing of the sinus node

Describe Renin-angiotensin-aldosterone system (RAAS) draw it out .

----kidneys detect------decrease in BP + decrease in Blood volume ----kidneys release-----renin ----Renin converts------angiotensinogen into angiotensinogen 1 ----ACE(circulatory enzymes secreted from Lungs endothelium)---- converts Angiotensin 1 into Angiotensin 2 ---Angiotensin 2---- causes vasoconstriction (peripheral resistance) =increase BP Aldosterone release (adrenal cortex)= ^ Na+ & H20 retention= ^ Blood vol.

ADH (VASOPRESSION) Mechanism describe? and draw

Baroreceptors detect decrease in BP __ __Osmooreceptos detetect increase in osmotic pressure( high solute concentration) hypothalmus

-----------thirst/ drinking (^ blood volume, decrease osmotic pressure)

-----------posterior pituitary releases ADH _________blood vessels vasoconstrict= ^ TPR +^ BP -----------kidneys increase H2o absorption= ^ Blood vol. and decrease osmotic pressure

ATRIAL stretch releases???

ANP is released in atria after stretch from too much venous return. antagonistic to aldosterone and angiotensin 2. -ANP promotes Na+ & H20 excretions in the urine by kidneys -promotes vasodilation, lowering TPR

ANP CANCELS OUT which hormones?

RENIN, ADH, ALDOSTERONE

cerebral blood flow is almost exclusively filled by ______________mechanisms

Cerebral blood flow (CBF) (IS or IS NOT) influenced by sympathetic nerve activity

BLOOD CELLs

45% , 5 million/µL = Erythrocyte (RBC) <1% , 150,000-400,000/µL = Thrombocyte <1% , 5,000-10,000/µL = Leukocyte 55% = Plasma

Types of leukocytes WBC %

Neutrophils = 60-70%, Lymphocytes = 20-25% Monocytes = 3-8% Eosinophils = 2-4%

Basophils are 0.5-1% of WBC's and are a elevated in the blood stream in response to allergy reaction or hypothyroid

True

AMOUNTS

Norm RBC = 5 million /UL Platlets (thorombocytes) = 150,000-400,000 /UL WBC = 5,000-10,000/UL Ratio = 700RBC/40PLAT/1WBC

Formation of Hemoglobin (Hb) dependent upon which vitamin__________

IN RBC, you have ___Globin (polypeptides) ___heme groups , where 02 attaches iron

match

Monocyte (LARGEST WBC) = machrophage Eosinophils = ALLERGIN, PARASITES Basophil = histamine secretion thrombocyte = clotting (cell fragment of megakaryocyte)

Where are blood cells from originally?

bone marrow

Test your knowledge of anatomy and physiology with questions about elastic arteries, muscular arteries, the sympathetic nervous system, the function of the circle of Willis, and the function of the hepatic portal vein.

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