Dermatology - Overview
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Questions and Answers

Which condition results from the reactivation of the varicella-zoster virus?

  • Contact Dermatitis
  • Shingles (Herpes Zoster) (correct)
  • Folliculitis
  • Impetigo

What is the primary cause of seborrheic dermatitis?

  • Allergic reaction to latex or detergents
  • Staphylococcus aureus bacterial infection
  • Exposure to plant irritants such as poison ivy
  • Overgrowth of Malassezia yeast (correct)

Which bacterial species are commonly responsible for impetigo?

  • Malassezia furfur and Candida albicans
  • Propionibacterium acnes and Corynebacterium diphtheriae
  • Staphylococcus aureus and Streptococcus pyogenes (correct)
  • Escherichia coli and Pseudomonas aeruginosa

A patient presents with a scaly, itchy rash primarily on the scalp and face. Which condition is most likely?

<p>Seborrheic Dermatitis due to yeast overgrowth (B)</p> Signup and view all the answers

Which condition involves inflammation and plugging of pilosebaceous units, leading to comedones, papules, and pustules?

<p>Acne (B)</p> Signup and view all the answers

A child presents with a red, raised rash and small bluish-white spots inside their mouth (Koplik spots). Which childhood disease is the most likely cause?

<p>Measles (B)</p> Signup and view all the answers

A patient presents with small, itchy pustules around hair follicles after using a public hot tub. What is the MOST likely cause, and what is the BEST initial treatment?

<p>Folliculitis; advise antibacterial soap (D)</p> Signup and view all the answers

An elderly woman experienced chickenpox as a child. She now presents with a painful, unilateral vesicular rash along a specific dermatome. Antiviral treatment is MOST effective if initiated within what timeframe, and what potential complication is the physician trying to prevent with early intervention?

<p>Within 72 hours; preventing postherpetic neuralgia (A)</p> Signup and view all the answers

Which skin condition is characterized by intensely pruritic, blistering rashes and is directly linked to coeliac disease?

<p>Dermatitis Herpetiformis (D)</p> Signup and view all the answers

A patient presents with raised, red, itchy wheals that appeared suddenly. Which condition is most likely?

<p>Urticaria (A)</p> Signup and view all the answers

Which of the following is the primary method of preventing Dermatitis Herpetiformis?

<p>Maintaining a strict gluten-free diet (D)</p> Signup and view all the answers

What is the MOST likely cause of heat rash (miliaria)?

<p>Excessive sweating and occlusion (D)</p> Signup and view all the answers

What is the MOST appropriate first-line treatment for mild acne?

<p>Topical retinoids or Benzoyl Peroxide (A)</p> Signup and view all the answers

What is a common characteristic used to describe Seborrheic Keratosis?

<p>A 'stuck-on' appearance (A)</p> Signup and view all the answers

A patient presents with small, soft skin growths on the neck and axillae. Which condition is MOST likely?

<p>Skin Tags (B)</p> Signup and view all the answers

What is the primary cause of increased melanin production in the skin?

<p>Sunlight exposure (C)</p> Signup and view all the answers

What is the primary cause of warts?

<p>Human papillomavirus (HPV) (B)</p> Signup and view all the answers

A patient presents with a bright red papule. What is the likely diagnosis?

<p>Cherry Angioma (B)</p> Signup and view all the answers

What is the main cause of Lentigo solar?

<p>Cumulative sun damage (D)</p> Signup and view all the answers

Hyperpigmentation related to systemic disease, such as Addison's disease, is caused by what?

<p>Endocrine disorders (C)</p> Signup and view all the answers

What triggers Erythema Multiforme (EM)?

<p>Infections and medications (A)</p> Signup and view all the answers

What is the origin of melanocytic naevi (moles)?

<p>Proliferation of melanocytes (A)</p> Signup and view all the answers

Psoriasis is characterized by well-demarcated, scaly plaques on specific areas of the body. Which areas are MOST commonly affected?

<p>Extensor surfaces (knees, elbows, scalp) (D)</p> Signup and view all the answers

What is the MOST important preventive measure for Lupus Erythematosus (LE)?

<p>Avoiding excessive sun exposure (A)</p> Signup and view all the answers

Which factor is the most significant contributor to the development of malignant melanoma?

<p>UV radiation (C)</p> Signup and view all the answers

What is the underlying cause of Bullous Diseases (Pemphigoid, Pemphigus)?

<p>Autoimmune reaction (D)</p> Signup and view all the answers

What is the most common type of skin cancer?

<p>Basal cell carcinoma (A)</p> Signup and view all the answers

A patient presents with a red, scaly rash around the mouth. Prolonged use of which substance is the MOST likely cause?

<p>Topical Steroids (B)</p> Signup and view all the answers

Squamous Cell Carcinoma (SCC) is a malignant tumor of what type of cells?

<p>Keratinocytes (B)</p> Signup and view all the answers

What is the primary mechanism of action for topical or systemic steroids in treating skin conditions?

<p>Suppressing immune/inflammatory response (B)</p> Signup and view all the answers

Which of the following conditions is characterized by flat, purple, pruritic papules and white lacy patches, often found on the wrists and oral mucosa?

<p>Lichen Planus (C)</p> Signup and view all the answers

Antihistamines relieve itching by blocking which receptors?

<p>Histamine receptors (A)</p> Signup and view all the answers

Which type of infection are antibiotic ointments or oral antibiotics used to treat?

<p>Bacterial infections (B)</p> Signup and view all the answers

What type of infections are antifungals used to treat?

<p>Fungal and yeast infections (B)</p> Signup and view all the answers

Aciclovir is an example of which type of medication?

<p>Antiviral (A)</p> Signup and view all the answers

For what purpose would a clinician use a dermatoscope?

<p>To examine skin lesions closely (C)</p> Signup and view all the answers

Regarding allergy testing, which of the following is not a method of allergy testing?

<p>Microbiological cultures (D)</p> Signup and view all the answers

Which of the following tests is most definitive for distinguishing between a benign versus malignant lesion?

<p>Biopsy (B)</p> Signup and view all the answers

A patient presents with redness, flushing and small papules on their face. Which skin condition is MOST likely?

<p>Rosacea (D)</p> Signup and view all the answers

A patient is diagnosed with Dermatitis Herpetiformis. What dietary change is MOST crucial for managing this condition?

<p>Gluten-free diet (D)</p> Signup and view all the answers

Which of the following conditions is directly associated with an autoimmune response targeting structural proteins within the skin layers, leading to blistering?

<p>Bullous Diseases (Pemphigoid, Pemphigus) (B)</p> Signup and view all the answers

What underlying physiological process causes heat rash (miliaria)?

<p>Blocked eccrine sweat ducts (C)</p> Signup and view all the answers

A patient presents with well-demarcated scaly plaques primarily on their elbows and knees. Histological examination reveals epidermal hyperproliferation and parakeratosis. Which of the following cytokines is MOST implicated in the pathogenesis of this condition?

<p>Tumor Necrosis Factor-alpha (TNF-α) (A), Interleukin-17 (IL-17) (B)</p> Signup and view all the answers

Which of the following is the MOST important first step in managing contact dermatitis?

<p>Identifying and avoiding the causative agent. (D)</p> Signup and view all the answers

A young child presents with honey-colored, crusted lesions around the nose and mouth. Which organism is MOST commonly responsible?

<p><em>Staphylococcus aureus</em> (A)</p> Signup and view all the answers

Which of the following is the MOST crucial intervention in reducing long-term complications associated with Shingles?

<p>Initiation of antiviral therapy within 72 hours of rash onset. (D)</p> Signup and view all the answers

A patient presents with numerous small, itchy pustules surrounding hair follicles on the legs, which they attribute to prolonged use of tight-fitting leggings. What is the MOST likely etiological factor?

<p>Bacterial colonization, most likely <em>Staphylococcus aureus</em>. (D)</p> Signup and view all the answers

A 6-year-old child, unvaccinated due to parental beliefs, presents with a high fever, cough, coryza, conjunctivitis, and pathognomonic bluish-white spots on the buccal mucosa. This presentation is MOST consistent with which of the following conditions?

<p>Measles (Rubeola) (C)</p> Signup and view all the answers

A patient presents with an intensely itchy rash after wearing a new bracelet. The rash is localized to the wrist and appears red and inflamed. Which of the following conditions is the MOST likely diagnosis?

<p>Contact Dermatitis (B)</p> Signup and view all the answers

Following several mosquito bites, a patient experiences significant itching and localized swelling. Which of the following medications would be MOST appropriate for immediate relief?

<p>Oral antihistamine (D)</p> Signup and view all the answers

A patient is diagnosed with folliculitis after using a public swimming pool. Which of the following organisms is LEAST likely to be the cause of this condition?

<p><em>Malassezia furfur</em> (D)</p> Signup and view all the answers

A 70-year-old patient, who had chickenpox as a child, presents with a painful, unilateral vesicular rash along the left side of their chest. They delayed seeking treatment until 4 days after the rash appeared. Which is the MOST critical next step in management?

<p>Administering antiviral medication, such as acyclovir, to reduce the duration and severity of the outbreak. (D)</p> Signup and view all the answers

During a measles outbreak, a 7-year-old unvaccinated child is exposed at school. The parents are hesitant about vaccination but seek advice on post-exposure prophylaxis. Which of the following is the MOST appropriate recommendation?

<p>Administering immunoglobulin (passive immunization) as soon as possible after exposure. (A)</p> Signup and view all the answers

What is a commonly used first-line topical treatment for mild acne vulgaris?

<p>Topical retinoids (A)</p> Signup and view all the answers

Which of the following is a known trigger that can exacerbate Rosacea symptoms?

<p>Sun exposure (B)</p> Signup and view all the answers

Lichen Planus is characterized by which distinctive skin findings?

<p>Flat, purple, pruritic papules with white lacy patches (A)</p> Signup and view all the answers

Bullous diseases, such as pemphigoid and pemphigus, are primarily caused by:

<p>Autoimmune reactions against structural proteins of the skin (A)</p> Signup and view all the answers

Dermatitis Herpetiformis, an intensely pruritic blistering rash, is strongly associated with and requires management of which systemic condition?

<p>Coeliac Disease (D)</p> Signup and view all the answers

Flashcards

Contact Dermatitis

Inflammatory skin reaction from irritants or allergens.

Insect Bites/Stings

Reaction to insect saliva or venom after a bite or sting.

Seborrheic Dermatitis

Scaly, itchy rash in areas with many sebaceous glands.

Impetigo

Superficial bacterial skin infection with crusting lesions.

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Shingles (Herpes Zoster)

Reactivation of varicella-zoster virus causing a painful, unilateral rash.

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Childhood Diseases

Viral infections with distinct rash patterns.

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Folliculitis

Inflammation/infection of hair follicles causing pustules and itch.

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Acne

Plugging and inflammation of pilosebaceous units.

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Hyperpigmentation

Increased melanin production, often triggered by sunlight or genetics.

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Lentigo Solar

“Sun spots” caused by chronic UV exposure.

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Systemic Disease-Related Hyperpigmentation

Skin darkening due to underlying endocrine disorders.

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Melanocytic Naevi (Moles)

Proliferations of melanocytes (pigment cells).

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Malignant Melanoma

Potentially lethal skin cancer arising from melanocytes.

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Basal Cell Carcinoma (BCC)

Most common form of skin cancer; slow-growing but locally invasive.

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Squamous Cell Carcinoma (SCC)

Malignant tumor of keratinocytes; can metastasize.

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Topical/Systemic Steroids

Inflammation in conditions like eczema, psoriasis, contact dermatitis.

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Antihistamines

Relieving itching (pruritus) in allergic reactions.

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Antibiotic Ointments/Oral Antibiotics

Treating bacterial skin infections (impetigo, folliculitis, acne).

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Antifungals

Fungal and yeast infections.

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Antivirals

Viral infections (e.g., shingles/herpes zoster).

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Immunosuppressants/Immunomodulators

Severe autoimmune or immune-mediated skin conditions.

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Surgery/Surgical Excision

Removes suspicious or cancerous lesions.

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Cryotherapy

Freezing off warts or small superficial BCCs.

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Rosacea

A chronic facial skin disorder causing redness, flushing, and sometimes papules/pustules.

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Perioral Dermatitis

Red, scaly rash around the mouth, sometimes nose/eyes.

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Lichen Planus

Immune-mediated condition with flat, purple, itchy papules and white lacy patches, often wrists/oral mucosa.

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Psoriasis

Chronic inflammatory skin disease with well-defined, scaly plaques on extensor surfaces (knees, elbows, scalp).

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Lupus Erythematosus (LE)

Autoimmune disease; discoid lupus affects skin only, while systemic lupus can involve multiple organs.

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Erythema Multiforme (EM)

Acute, self-limiting condition with target lesions, often triggered by HSV infections or medications.

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Bullous Diseases

Autoimmune blistering disorders affecting skin/mucous membranes.

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Dermatitis Herpetiformis

Intensely itchy, blistering rash linked with coeliac disease.

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Atopic Dermatitis (Eczema)

Chronic inflammatory skin disorder with itchiness, dryness; part of the atopic triad (asthma, hay fever).

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Urticaria (Hives)

Raised, red, itchy wheals on the skin; can be acute or chronic.

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Heat Rash (Miliaria)

Small, itchy bumps due to blocked sweat ducts in hot/humid conditions.

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Seborrheic Keratosis

Very common benign skin growth with a “stuck-on” appearance, often in older adults.

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Skin Tags (Acrochordons)

Small, soft, pedunculated skin growths in areas of friction (neck, axillae).

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Warts

Small, rough skin growths caused by HPV.

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Cherry Angioma

Bright red papules formed by benign proliferation of blood vessels.

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Ephelis (Freckles)

Flat, pigmented spots on sun-exposed areas.

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Study Notes

Contact Dermatitis

  • An inflammatory reaction on the skin occurs after exposure to irritants or allergens.
  • Chemicals like latex and detergents can cause it.
  • Plant irritants, such as poison ivy, are also causes.
  • Cosmetics can also trigger this condition.
  • Treatment involves avoiding triggers.
  • Topical steroids are used for inflammation relief.
  • Emollients are also used in treatment.
  • Prevention involves identifying and minimizing contact with known irritants.

Insect Bites/Stings

  • A local or systemic reaction to insect saliva or sting venom.
  • Mosquitoes, bees and ticks can cause these reactions.
  • Treatment includes cleaning the area and applying a cold compress.
  • Antihistamines can relieve itching.
  • Severe reactions may require medical care.
  • Prevention involves wearing protective clothing and using repellents.
  • Avoiding infested areas also helps prevent bites and stings.

Seborrheic Dermatitis

  • A scaly, itchy rash appears in areas with many sebaceous glands, like the scalp and face.
  • An overgrowth of Malassezia yeast causes it.
  • Treatment includes medicated shampoos and antifungal creams.
  • Mild topical steroids are also used.
  • Prevention means reducing triggers like stress or harsh weather.

Impetigo

  • A superficial bacterial infection with crusting lesions, often found in children.
  • Staphylococcus aureus or Streptococcus pyogenes causes it.
  • Treatment involves topical or oral antibiotics.
  • Hygiene measures are also important.
  • Prevention includes good hygiene and prompt care of minor skin injuries.

Shingles (Herpes Zoster)

  • Reactivation of the varicella-zoster virus causes a unilateral vesicular rash.
  • It is caused by a latent virus from an earlier chickenpox infection.
  • Antiviral therapy such as aciclovir should begin within 72 hours to reduce complications.
  • The condition requires pain management.
  • Prevention involves vaccination for eligible older adults.
  • Avoiding triggers is helpful if immunocompromised.

Childhood Diseases (Measles, Rubella, etc.)

  • Viral exanthems with distinct rash patterns occur, sometimes with oral signs such as Koplik spots in measles.
  • Various viruses cause them, including measles and rubella.
  • Treatment involves supportive care.
  • Some diseases have preventive vaccines, like MMR.
  • Prevention is achieved through vaccination programs.

Folliculitis

  • It is the inflammation or infection of hair follicles that causes pustules and itch.
  • Bacteria such as Staphylococcus causes it.
  • Friction can be a cause, as well as occlusion.
  • Treatment involves antibacterial soap.
  • Topical or oral antibiotics are used if needed.
  • Prevention involves proper hygiene and avoiding tight clothing.

Acne

  • Plugging and inflammation of pilosebaceous units results in comedones, papules, or pustules.
  • Hormonal changes, genetics, and some medications cause this.
  • Treatment involves topical retinoids and benzoyl peroxide.
  • Oral antibiotics or isotretinoin are also used for severe cases.
  • Prevention consists of gentle skin care, avoiding picking lesions, and managing triggers.

Rosacea

  • A chronic facial skin disorder that causes redness, flushing, and sometimes papules or pustules.
  • The exact cause is unknown.
  • Triggers include sun, alcohol, spicy foods, and stress.
  • Treatment involves avoiding triggers and using topical metronidazole.
  • Oral antibiotics and laser therapy for telangiectasia are also treatment forms.
  • Prevention includes protective measures against known triggers.

Perioral Dermatitis

  • A red, scaly rash around the mouth, sometimes nose or eyes.
  • Topical steroids and heavy facial creams cause it.
  • Immunological factors, and possibly microbes can cause this.
  • Treatment involves stopping irritants like steroids, creams, and topical or oral antibiotics.
  • Prevention means avoiding prolonged topical steroid use on the face and maintaining a mild skincare routine.

Lichen Planus

  • An immune-mediated condition with flat, purple, pruritic papules and white lacy patches, often on wrists or oral mucosa.
  • It has an autoimmune basis with an unknown trigger.
  • Treatment involves topical or systemic steroids.
  • Immunosuppressants are used in severe cases.
  • There is no definitive prevention, but stress management may help reduce flares.

Psoriasis

  • A chronic inflammatory skin disease with well-demarcated, scaly plaques on extensor surfaces like knees, elbows, and scalp.
  • It is due to autoimmune mechanisms and genetic predisposition.
  • Treatment involves emollients and topical steroids.
  • Vitamin D analogues and phototherapy are also treatments, as well as systemic agents in severe cases.
  • It is not strictly preventable, but triggers like stress and skin trauma can worsen flares.

Lupus Erythematosus (LE)

  • An autoimmune disease where discoid lupus affects skin only, while systemic lupus can involve multiple organs.
  • It is caused by autoimmune dysfunction, possibly triggered by UV light or genetics.
  • Treatment uses topical or systemic steroids and immunosuppressants.
  • Sun protection is important.
  • Prevention is avoiding excessive sun exposure and managing triggers.

Erythema Multiforme (EM)

  • An acute, self-limiting condition with target lesions, often triggered by infections such as HSV or medications.
  • An immune response to infections or drugs causes this condition.
  • Treatment includes identifying and removing the trigger.
  • Supportive care and sometimes steroids may have to be provided.
  • Prevention is prophylaxis in recurrent HSV-induced EM if indicated.

Bullous Diseases (Pemphigoid, Pemphigus)

  • Autoimmune blistering disorders affecting skin and mucous membranes.
  • Autoantibodies targeting structural proteins in skin layers causes this condition.
  • Treatment involves high-potency topical or systemic steroids and immunosuppressants.
  • Not specifically preventable, but early diagnosis helps minimize complications.

Dermatitis Herpetiformis

  • Intensively pruritic, blistering rash linked with coeliac disease.
  • An autoimmune reaction to gluten in genetically predisposed individuals causes the conditions.
  • Treatment involves a gluten-free diet and dapsone.
  • Prevention involves maintaining a strict gluten-free diet if coeliac disease is confirmed.

Atopic Dermatitis (Eczema)

  • A chronic inflammatory skin disorder with itchiness, dryness, and often part of the atopic triad with asthma and hay fever.
  • It is caused by genetic predisposition, immune dysregulation, and environmental triggers.
  • Treatment uses emollients and topical steroids.
  • Avoiding irritants is also important.
  • Prevention includes moisturizing, allergen avoidance, and controlling triggers.

Urticaria (Hives)

  • Raised, red, itchy wheals on the skin that can be acute or chronic.
  • Allergic triggers such as foods, drugs, and stings cause it.
  • Physical factors or idiopathic factors can be causal.
  • Treatment involves antihistamines.
  • Avoidance of known allergens is also important.
  • Epinephrine is needed if severe (anaphylaxis).
  • Prevention involved identifying triggers and carrying emergency medication if needed.

Heat Rash (Miliaria)

  • Small, itchy bumps due to blocked sweat ducts in hot or humid conditions.
  • Excessive sweating and occlusion causes it.
  • Treatment includes cooling down, wearing loose clothing, and applying calamine lotion if needed.
  • Prevention includes keeping skin cool and avoiding overheating.

Seborrheic Keratosis

  • A very common benign skin growth with a “stuck-on” appearance, often in older adults.
  • The cause is unknown but linked to aging.
  • Generally, no treatment is required unless irritated or cosmetically undesired, in which case cryotherapy or curettage can solve this.
  • There is no specific prevention, and these are common benign growths.

Skin Tags (Acrochordons)

  • Small, soft, pedunculated skin growths in areas of friction (neck, axillae).
  • Friction, genetics, and possibly insulin resistance cause them.
  • Often removed for cosmetic reasons or if irritated (snip excision, cryotherapy).
  • Reducing friction (e.g., weight management) may help, but is not guaranteed.

Warts

  • Small, rough skin growths caused by HPV.
  • Human papillomavirus infecting the epidermis causes this.
  • Treatment involves cryotherapy, salicylic acid, or other destructive methods, however they can be persistent.
  • Prevention involves avoiding direct contact with warts and keeping skin healthy and unbroken.

Cherry Angioma

  • Bright red papules formed by benign vascular proliferation
  • The cause is unclear, possibly genetics and age-related
  • Treatment is not necessary unless bleeding or a cosmetic concern exists (laser removal).
  • There is no specific prevention, and these are generally harmless.

Ephelis (Freckles)

  • Flat, pigmented spots on sun-exposed areas.
  • Increased melanin production, triggered by sunlight and genetic factors, causes them.
  • No treatment is needed; cosmetic options exist.
  • Prevention means sun protection (sunscreens, hats).

Lentigo Solar

  • Sun spots due to chronic UV exposure and age.
  • Cumulative sun damage causes them.
  • Cosmetic removal (e.g., laser) can remove them if desired; otherwise harmless
  • Prevention involves sun protection (SPF, limited tanning).
  • Generalized or localized darkening of the skin.
  • Underlying endocrine disorders like Addison’s disease causes them.
  • Treatment involves addressing the underlying systemic disease.
  • Not directly preventable unless controlling the primary disease.

Melanocytic Naevi (Moles)

  • Proliferations of melanocytes (pigment cells) that can be congenital or acquired.
  • Genetics, possibly influenced by hormones or immunosuppressive drugs, causes them.
  • Usually, no treatment unless suspicious changes are noted; surgical excision if necessary.
  • Sun protection can reduce the risk of atypical transformation.

Malignant Melanoma

  • A potentially lethal skin cancer arising from melanocytes that can metastasize quickly.
  • UV radiation and genetic predisposition can cause it.
  • Surgical excision with adequate margins is treatment.
  • Advanced disease may require immunotherapy or targeted therapy.
  • Prevention involves vigilant sun protection, self-exams, and early detection

Basal Cell Carcinoma (BCC)

  • The Most common form of skin cancer, it is slow-growing but locally invasive.
  • Chronic sun exposure, fair skin, and older age causes this.
  • Treatment involves surgical excision, curettage, cryotherapy, or radiotherapy.
  • Prevention involves sun protection and monitoring suspicious lesions early.

Squamous Cell Carcinoma (SCC)

  • A malignant tumor of keratinocytes can metastasize if not caught early.
  • Sun exposure, immunosuppression, older age, and smoking cause this.
  • Treatment involves surgical excision, often with wider margins than with BCC, and sometimes radiotherapy.
  • Prevention includes sun protection and avoidance of risk factors like tobacco and excessive UV.

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