Quinine Sulphate (Malacam®) in Falciparum Malaria Treatment Quiz
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Questions and Answers

Which drug is indicated for the treatment of Falciparum malaria and has a mechanism of action as a schizontocide against various Plasmodium species?

Quinine Sulphate (Malacam®)

What is the recommended duration of treatment for adults with quinine sulfate/bisulfate tablets in the treatment of Falciparum malaria?

600 mg 8 hourly for 7 days

What additional follow-on treatment may be given in uncomplicated infections if resistance to quinine sulfate is known or suspected?

Doxycycline or clindamycin

What is the recommended dosage of quinine sulfate/bisulfate tablets for children in the treatment of Falciparum malaria?

<p>10 mg/kg 8 hourly for 7 days</p> Signup and view all the answers

What is the mechanism of action of quinine in the treatment of malaria?

<p>Quinine depresses oxygen uptake and carbohydrate metabolism, and intercalates into the parasite’s DNA, thereby disrupting its replication and transcription.</p> Signup and view all the answers

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