Firsto labbo krino

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Questions and Answers

Indicate and describe the Macroscopic and Microscopic morphologic features typical for Grave's disease

Macroscopically: Diffuse goiter, fleshy tissue Microscopically: decreased amount of colloid, increased height of follicular epithelium, local proliferation of follicular epithelium

Explain what are the classification of pituitary gland's tumors (5 types)

Somatotroph: excess growth hormone, acromegaly or gigantism Lactotroph: excess prolactin, menstrual irregularities, infertility, gynecomastia Thyrotroph: excess TSH, hyperthyroidism Corticotroph: excess ACTH, cushings disease Gonadotroph: excess FSH/LH, reproductive issues

Explain what are the classification of pathologic calcification (2 types)

Dystrophic calcification: normal Ca metabolism + Ca accumulates in injured or dead tissue

Metastatic calcification: hypercalcemia + Ca accumulates in regular tissue, caused by hyperthyroidism

Hypopituitarism hyperpituitarism meaning and cause

Decreased functional activity of tropic hormones of adenohypophysis caused by compression of adeno, increased functional activity of tropic hormones of adenohypophysis, caused by overactivated by a tumor Signup and view all the answers

Mechanism of Grave's disease

It is a hypersensitivity type 2 reaction, cytotoxic Signup and view all the answers

Clinical symptoms of Cushing's syndrome

Moon face, central type obesity, decreased strength and weight of muscles, hyperglycemia, impaired sexual function Signup and view all the answers

Explain Addisons disease

Chronic adrenal gland condition due to decreased functional activity. caused by infections, autoimmune disease, neoplasms. Clinical features are weakness, appetite and wight loss , skin hyperpigmentation, hypotension Signup and view all the answers

Explain what is Grave's disease?

A pathological thyroid gland condition with thyrotoxicosis, diffuse goiter and infiltrative ophthalmopathy (40%). Hypersensitivity type 2. Increased T3 and T4. Signup and view all the answers

What is pheochromocytoma, features and symptoms

Benign neoplasm of adrenal medulla -> secrete dopamine, noradrenaline, adrenaline. Morphological features -> encapsulated, greyish tissue, some areas of necrosis and haemorrhages Symptoms: Secondary hypertension, hyperglycemia, lipolysis, tachycardia Signup and view all the answers