Pulmonary Volumes and Capacities Quiz

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Questions and Answers

What is the primary cause of hypoxemia in pneumonia?

  • Increased lung compliance
  • Respiration in the pleural cavity
  • Enhanced gas exchange in inflamed areas
  • Increased shunting of blood to non-ventilated areas (correct)

What is the role of fibrin and edema in pneumonia?

  • To decrease lung compliance and vital capacity (correct)
  • To promote blood flow to alveoli
  • To facilitate gas exchange
  • To increase lung compliance

Which phase of pneumonia is characterized by the movement of RBCs and fibrin into the alveoli?

  • Inflammatory phase
  • Red hepatization phase (correct)
  • Gray hepatization phase
  • Resolution phase

Which organism is most commonly associated with community-acquired pneumonia?

<p>Streptococcus pneumoniae (C)</p> Signup and view all the answers

What complication can result if the infection extends into the pleural cavity?

<p>Empyema or abscess (D)</p> Signup and view all the answers

Which of the following is NOT a common risk factor for hospital-acquired pneumonia?

<p>Recent flu vaccination (D)</p> Signup and view all the answers

What effect does pneumonia have on the compliance of the lungs?

<p>Decreases lung compliance (D)</p> Signup and view all the answers

Which patient characteristic increases the risk of aspiration pneumonia?

<p>Altered level of consciousness (B)</p> Signup and view all the answers

What is a common early sign of confusion in older adults experiencing respiratory issues?

<p>Confusion (A)</p> Signup and view all the answers

Which of the following is a direct cause of Acute Lung Injury (ALI)?

<p>Bacterial pneumonia (A)</p> Signup and view all the answers

Which symptom indicates possible involvement of the accessory muscles during respiratory distress?

<p>Use of accessory muscles (D)</p> Signup and view all the answers

What distinguishes ARDS from ALI?

<p>Severe injury and inflammation (D)</p> Signup and view all the answers

What does E-A egophony indicate during a respiratory examination?

<p>Thickened alveolar walls (D)</p> Signup and view all the answers

Which of the following is an indirect cause of ALI?

<p>Pancreatitis (B)</p> Signup and view all the answers

In a patient with decreased oxygen saturation, which of the following symptoms may be present?

<p>Hypotension (A)</p> Signup and view all the answers

What is the most common cause of Acute Lung Injury?

<p>General sepsis (A)</p> Signup and view all the answers

What is the primary function of the Ventral Respiratory Group (VRG)?

<p>Act solely during overdrive to enhance inspiratory and expiratory efforts (C)</p> Signup and view all the answers

What causes an obstructive pulmonary problem according to the general pathology?

<p>Increase in resistance to airflow at any level of the bronchial tree (B)</p> Signup and view all the answers

Which statement accurately describes the changes in pulmonary function tests (PFT) associated with severe obstructive disease?

<p>Decreased VC, FEV1, FEV1/FVC, and PERF with increased FRC and RV (A)</p> Signup and view all the answers

What is the primary pathological change in emphysema?

<p>Permanent enlargement of acini and destruction of alveolar walls (B)</p> Signup and view all the answers

What role do peripheral chemoreceptors play in respiratory regulation?

<p>They are crucial in detecting decreased O2 levels (C)</p> Signup and view all the answers

How do inspiratory 'Ramp' signals affect lung filling?

<p>They cause a gradual increase in inspiratory neuron activity (D)</p> Signup and view all the answers

What are the consequences of alveolar destruction in emphysema?

<p>Trapping of air in the lungs and decreased recoil (D)</p> Signup and view all the answers

Which accessory organ is primarily responsible for the secretion of digestive enzymes into the duodenum?

<p>Exocrine pancreas (B)</p> Signup and view all the answers

What is the primary function of the villi in the mucosa layer of the digestive tract?

<p>Increasing surface area for absorption (B)</p> Signup and view all the answers

What is typically the most common cause of intussusception in the small bowel?

<p>Telescoping of bowel (D)</p> Signup and view all the answers

What is consistent with restrictive disease characterized by pulmonary function tests?

<p>Decreased VC, FEV1, and normal FEV1/FVC (C)</p> Signup and view all the answers

Which clinical manifestation is characteristic of upper gastrointestinal bleeding?

<p>Coffee ground emesis (A)</p> Signup and view all the answers

Which layer of the digestive tract contains the submucosal plexus?

<p>Submucosa (A)</p> Signup and view all the answers

What commonly causes acute pancreatitis related to alcohol consumption?

<p>Acetaldehyde metabolite (B)</p> Signup and view all the answers

What distinguishes exocrine glands from endocrine glands?

<p>Exocrine glands empty into ducts. (D)</p> Signup and view all the answers

Which of the following is NOT a component of the innermost tunic of the digestive tract?

<p>Circular smooth muscle (A)</p> Signup and view all the answers

Which of the following is a potential cause of lower gastrointestinal bleeding?

<p>Diverticulosis (B)</p> Signup and view all the answers

What is the primary movement facilitated by the outer layer of longitudinal smooth muscle in the muscularis layer?

<p>Peristalsis (D)</p> Signup and view all the answers

What is a common clinical manifestation of ileus?

<p>Low peristalsis and nausea/vomiting (D)</p> Signup and view all the answers

What is a common etiology for superficial mucosal ulcers?

<p>NSAIDs (C)</p> Signup and view all the answers

What clinical manifestation is NOT typically associated with gastroparesis?

<p>Diarrhea (D)</p> Signup and view all the answers

Which structure forms a double layer of peritoneum that supports the intestines?

<p>Mesentery (B)</p> Signup and view all the answers

What is the primary component of gallstones in cholelithiasis?

<p>Cholesterol (A)</p> Signup and view all the answers

What is the main role of the enteric nervous system in the digestive tract?

<p>Managing movement and secretion within the tract (B)</p> Signup and view all the answers

Which type of bowel obstruction is most associated with a twisted loop of intestines?

<p>Volvulus (B)</p> Signup and view all the answers

Which type of hiatal hernia is the most common?

<p>Type 1 (sliding) (D)</p> Signup and view all the answers

What is a consequence of chronic hyperglycemia in the context of gastroparesis?

<p>Neuron damage (C)</p> Signup and view all the answers

What is the typical dilation measurement indicating a bowel obstruction?

<p>Greater than 3 cm (B)</p> Signup and view all the answers

Which of the following is NOT a treatment method for peptic ulcer disease?

<p>Surgical intervention (A)</p> Signup and view all the answers

What type of clinical manifestations are typically associated with a hiatal hernia?

<p>Gastroesophageal reflux disease (GERD) symptoms (B)</p> Signup and view all the answers

What is a key characteristic of peptic ulcer disease compared to gastritis?

<p>Extension into the muscularis layer (C)</p> Signup and view all the answers

Which of the following factors is NOT a known trigger for superficial mucosal ulcer development?

<p>High sugar intake (B)</p> Signup and view all the answers

Flashcards

Ventral Respiratory Group (VRG)

The primary inspiratory center in the brain stem, which doesn't change its basic rhythm, only the pattern.

Inspiratory Ramp

A gradual increase in inspiratory neuron firing, causing smooth lung filling instead of gasping breaths.

Central Chemoreceptors

Brain receptors sensitive to increasing CO2 and H+ levels in the blood, triggering a breathing response.

Peripheral Chemoreceptors

Blood vessel receptors sensitive to low O2 (hypoxia), triggering a breathing response.

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Obstructive Pulmonary Problems

Problems that reduce airway size, increasing airflow resistance, causing chronic airflow limitation.

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Emphysema Pathology

A lung condition causing permanent enlargement of air sacs and destruction of alveolar walls, decreasing lung elasticity & gas exchange

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Restrictive Lung Disease

Lung problems decreasing lung volume and causing decreased vital capacity while maintaining normal ratio of FEV1/FVC.

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Severe Obstructive Disease

Lung problems causing decreased airflow, increased air trapping and a lowered FEV1/FVC ratio .

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Pneumonia Pathophysiology

Inflammatory lung response with fluid buildup in alveoli, causing low blood oxygen levels (hypoxemia).

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Pneumonia Triggers (Community-Acquired)

Factors increasing risk of community-acquired pneumonia, including age, vaccination history, chronic conditions, and exposure to respiratory illnesses.

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Pneumonia Triggers (Hospital-Acquired)

Factors increasing risk of hospital-acquired pneumonia, such as pre-existing conditions, altered consciousness, use of respiratory aids, and weakened immune systems.

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Bacterial Pneumonia

Pneumonia primarily caused by bacteria, often Streptococcus.

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Lung Compliance

Ability of the lungs to expand and contract during breathing, reduced by pneumonia-related fluid.

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Hypoxemia in Pneumonia

Low blood oxygen levels due to impaired gas exchange in pneumonia-affected lung regions.

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Aspiration Pneumonia

Pneumonia that develops from inhaling foreign substances into the lungs

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Septicemia

Blood infection resulting from bacteria reaching the bloodstream in pneumonia.

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ALI/ARDS Symptoms

Symptoms include fever, headache, chills, myalgia, cough (except in older adults), tachypnea, tachycardia, dyspnea, decreased oxygen saturation, sputum production (may be absent in older adults), use of accessory muscles, crackles/wheezing, pleuritic pain, dehydration, hypotension, confusion (especially in older adults), increased fremitus, decreased resonance, and egophony (E-A change).

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ALI Pathophysiology

ALI (Acute Lung Injury) is a serious lung inflammation continuum resulting from internal or external pulmonary assaults. It can occur without ARDS (Acute Respiratory Distress Syndrome), which generally follows ALI. It's often caused by sepsis.

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ALI/ARDS Causes (Direct)

Direct causes of ALI include chest trauma, inhaled toxins, aspiration, near-drowning, fat embolism syndrome, pneumonia (including COVID), drug/chemical exposure, oxygen toxicity, and high-altitude sickness.

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ALI/ARDS Causes (Indirect)

Indirect causes of ALI include sepsis (and SIRS), MODS (Multiple Organ Dysfunction Syndrome), DIC (Disseminated Intravascular Coagulation), massive transfusions, pancreatitis, and wide-spread inflammation.

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ARDS Definition

ARDS (Acute Respiratory Distress Syndrome) is a severe respiratory insufficiency and inflammation. It's characterized by progressive hypoxemia (low blood oxygen) that's resistant to high oxygen therapy.

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ALI Definition

ALI (Acute Lung Injury) is acute inflammation and injury to the alveolocapillary membranes, disrupting the integrity of the endothelial/epithelial barrier. It's associated with any event disrupting this barrier and approximately 40% of ALI progresses to ARDS.

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Decreased Resonance

Decreased lung resonance is a sign in lung conditions where fewer air-filled spaces are present, often due to thickened alveolar walls. This reduces the transmission of sound waves through the lungs.

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Increased Fremitus

Increased fremitus is an indicator that sound waves travel better through denser tissue in the lungs, suggesting possible consolidation or fluid build-up. In the case of pneumonia or other diseases that cause swelling or thickening the transmission of vibrations through chest wall will be better.

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Mucosal Ulcers

Superficial sores on the lining of the digestive tract, sometimes with bleeding.

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NSAID Ulcer Cause

Non-steroidal anti-inflammatory drugs (NSAIDs) can cause ulcers by reducing the protective mucus layer in the stomach.

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Gastroparesis Etiology

Poorly controlled diabetes often leads to gastroparesis, a condition of delayed stomach emptying.

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Gastroparesis Symptoms

Gastroparesis results in symptoms like vomiting, fullness after meals, nausea, and bloating; possibly constipation or diarrhea.

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Hiatal Hernia Types

Hiatal hernias, where part of the stomach slides into the chest, have various types based on how much of the stomach is involved: sliding (Type 1), paraesophageal (Type 2), and others.

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Hiatal Hernia Cause

Hiatal hernias can be caused by congenital factors, age, or increased pressure in the abdomen.

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Peptic Ulcer Location

Peptic ulcers commonly develop in the stomach and the beginning of the small intestine(duodenum).

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Ulcer Bleeding Risk

Ulcers that penetrate deeper into the stomach wall are at higher risk of bleeding compared to superficial ulcers.

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Accessory Digestive Organs

Organs that aid digestion but are not part of the digestive tract's main pathway. These include salivary glands, liver, gallbladder, and pancreas.

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Exocrine Pancreas Function

The exocrine pancreas secretes digestive enzymes, ions, and water into the duodenum (small intestine), which aids in breaking down food.

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GI Tract Layers

The digestive tract has four layers: Mucosa (innermost), Submucosa, Muscularis (smooth muscle), and Serosa (outer).

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Mucosa Layer Function

The innermost layer of the GI tract containing epithelium, connective tissue, and a thin muscle layer; increases surface area for absorption, especially with villi.

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Submucosa Layer Function

The layer under the mucosa with nerves, blood vessels, and glands that release secretions into the intestinal lumen; important in regulating digestion.

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Muscularis Layer Description

The smooth muscle layer in the GI tract with an inner circular and outer longitudinal layer. This allows for contractions and peristalsis for moving food along the tract.

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Serosa Layer Role

The outermost layer of the GI tract, composed of a smooth tissue layer. It reduces friction as it's against the organs.

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Enteric Nervous System

A network of nerve plexuses within the submucosa and muscularis layers that controls movement and secretion in the digestive tract.

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Bowel Obstruction

A blockage in the small or large intestine, causing partial or complete obstruction, usually identified by dilation (over 3cm).

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Transition Point (bowel)

The location where a dilated section of bowel changes to a compressed one.

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Upper GI bleed

Bleeding from the esophagus, stomach, or beginning of the small intestines (above the ligament of Treitz).

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Lower GI bleed

Bleeding from the small intestines (below the ligament of Treitz) or colon.

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Acute Pancreatitis

Inflammation and autodigestion of the pancreas usually caused by alcohol.

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Cholelithiasis

Gallstones, often cholesterol-based, can cause cholestasis.

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Ileus

Lack of peristalsis (bowel movement) due to low-flow states (or other disruptions).

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Types of Bowel Obstructions

Bowel obstructions can be caused by adhesions, tumors, hernias, intussusception, volvulus, and intaluminar lesions.

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Study Notes

Pulmonary Volumes and Capacities

  • Tidal Volume (TV): Volume of air inhaled and exhaled with each normal breath, approximately 500 mL.
  • Minute Volume: Volume of air inhaled and exhaled in one minute, calculated by multiplying TV by respiratory rate (about 8L).
  • Alveolar Volume: Difference between TV and dead space volume (about 350 mL).
  • Inspiratory Reserve Volume (IRV): Extra volume of air that can be inhaled beyond normal tidal volume (about 3000 mL). It's a measure of pulmonary compliance and inspiratory muscle strength. Reduced IRV suggests reduced lung compliance or weakened inspiratory muscles.
  • Expiratory Reserve Volume (ERV): Volume of air that can be forcefully exhaled after a normal tidal inhalation (about 1100 mL). Increased ERV indicates improved expiratory muscle strength; decreased ERV suggests weaker muscles, airway obstruction, or restrictive disorders.
  • Residual Volume (RV): Volume of air remaining in the lungs after the most forceful exhalation (about 1200 mL). Increased RV can be an indicator of aging or reduced ventilation effectiveness.
  • Forced Expiratory Flow (FEF) / Peak Expiratory Flow (PEF): Airflow rate during forced expiration. Reductions greater than 25% of PEFR are suggestive of obstructive respiratory disorders.
  • Forced Expiratory Volume 1 (FEV1): Maximum volume of air that can be forcefully exhaled in the first second after maximal inhalation (normally 80% of average). This is a sensitive measure for obstructive airway disorders.
  • Diffusing Capacity of the Lung for Carbon Monoxide (DLCO): Measures how well gas moves from the alveoli into the blood. Lower DLCO values suggest alveolar problems like emphysema, pneumonia, or pulmonary edema.

Pulmonary Capacities

  • Inspiratory Capacity (IC): Volume of air that can be inspired from rest to the maximum possible level, equal to 3500 mL (Tidal Volume + Inspiratory Reserve Volume). Reduced IC suggests restrictive lung disease.
  • Functional Residual Capacity (FRC): Volume of air remaining in the lungs at the end of a normal tidal breath, equal to 2300mL (Expiratory Reserve Volume + Residual Volume). Increases suggest obstructive lung diseases.
  • Vital Capacity (VC): Maximum volume of air that can be expelled from the lungs after maximum inhalation, equal to 4600 mL (Inspiratory Reserve Volume + Tidal Volume + Expiratory Reserve Volume).
  • Total Lung Capacity (TLC): Maximum volume of air lungs can hold equal to 6 liters (Tidal Volume + Inspiratory Reserve Volume + Expiratory Reserve Volume + Residual Volume). Reduced TLC suggests restrictive disease. Forced Vital Capacity (FVC) is the maximum volume of air exhaled as rapidly as possible after maximal inhalation.

Pulmonary Functions

  • Ventilation: Movement of air into and out of lungs for gas exchange.
  • Perfusion: Circulation of blood through tissues and organs for gas exchange.
  • Diffusion: Movement of O2 and CO2 molecules across permeable membranes due to pressure differences.
  • Regulation of oxygenation and gas exchange: Vital function of lungs
  • Protection: Lungs defend against pathogens and irritants, mainly by macrophages and surfactant.
  • Maintenance of cardiac output: Function of the lungs to support cardiac function and blood pressure.
  • Immunity: Lungs role in immune defense.
  • Fluid, electrolyte, and acid-base balance: Lungs play a minor role in these processes.

Other Pulmonary Information

  • Anatomic Dead Space: Volume of airways where gas exchange cannot occur, usually 150 mL
  • Physiological Dead Space: Total volume of airways where gas exchange cannot occur. Includes anatomical dead space plus additional areas of non-functional tissue.

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