Pulmonary Ventilation Techniques Quiz

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Questions and Answers

What does the acronym VQ stand for in nuclear medicine?

  • Ventilation and Quantification
  • Ventilation Quantitative
  • Ventilation and Perfusion (correct)
  • Vascular Quality

What is the primary purpose of conducting lung scans?

  • To rule out pulmonary embolism (correct)
  • To assess lung capacity
  • To monitor post-operative lung function
  • To evaluate for chronic obstructive pulmonary disease

Which statement is true about the performance of lung scans?

  • They should only be performed in outpatient settings.
  • They must be performed in a single step only.
  • They can be scheduled weeks in advance for any condition.
  • They are usually ordered as immediate emergency procedures. (correct)

How does a low probability VQ scan differ from a high probability VQ scan for pulmonary embolism?

<p>High probability indicates a greater likelihood of PE. (C)</p> Signup and view all the answers

What technique is used for a quantitative lung scan as part of nuclear medicine?

<p>Xenon 133 gas ventilation (C)</p> Signup and view all the answers

During a VQ scan, what specific symptoms might a patient typically exhibit?

<p>Shortness of breath and chest pain (C)</p> Signup and view all the answers

What is one of the steps to be followed when performing a VQ scan?

<p>Performing ventilation and perfusion together (D)</p> Signup and view all the answers

What distinguishes a quantitative lung scan from traditional lung scans?

<p>Quantitative scans measure the blood flow in the lungs. (D)</p> Signup and view all the answers

What is the approximate number of small capillaries in the lungs?

<p>280 billion (A)</p> Signup and view all the answers

What is the typical ratio of right lung uptake to left lung uptake?

<p>55% to 45% (A)</p> Signup and view all the answers

What is a potential complication of injecting micro emboli into the lungs?

<p>Blockage of capillaries (B)</p> Signup and view all the answers

What does the VQ consist of?

<p>Ventilation and perfusion studies (C)</p> Signup and view all the answers

What might cause the left lung to show less uptake than the right lung?

<p>Overlay of the heart (D)</p> Signup and view all the answers

Which of the following is NOT typically included in a VQ scan?

<p>Conductivity measurement (C)</p> Signup and view all the answers

How many regions are commonly compared in lung segment analysis?

<p>4 regions (B)</p> Signup and view all the answers

When comparing total counts in lung segments, what is measured?

<p>Counts from each segment and both lungs combined (A)</p> Signup and view all the answers

What might affect uptake percentages in lung studies?

<p>Heart position relative to the lungs (C)</p> Signup and view all the answers

What study is usually a standalone examination in lung diagnostics?

<p>Lung quantification (A)</p> Signup and view all the answers

What is usually indicated by the presence of a triangular wedge during a lung perfusion study?

<p>Pulmonary embolism (D)</p> Signup and view all the answers

Which lung condition may show clumpy areas due to particle deposition?

<p>COPD (D)</p> Signup and view all the answers

In a ventilation study, what does normal ventilation with abnormal perfusion indicate?

<p>Pulmonary embolism (D)</p> Signup and view all the answers

What might be a consequence of using a larger amount of the isotope in patients with pulmonary hypertension?

<p>Increased risk of respiratory distress (A)</p> Signup and view all the answers

How do obstruction presentations in lung imaging typically manifest?

<p>Bronchial branching missing or reduced (B)</p> Signup and view all the answers

What does accelerated clearance of aerosols in lung imaging suggest?

<p>Chronic interstitial lung disease (A)</p> Signup and view all the answers

Why is the perfusion portion crucial in lung studies?

<p>To identify blood flow issues such as clots (C)</p> Signup and view all the answers

Which of the following is a contraindication for lung perfusion studies?

<p>Pulmonary hypertension (C)</p> Signup and view all the answers

What is the significance of the ventilation study in diagnosing conditions like COPD?

<p>It correlates with chest X-ray findings (A)</p> Signup and view all the answers

What is the risk of using too many particles in the perfusion study?

<p>Potential lung obstruction (A)</p> Signup and view all the answers

What happens to ventilation findings when a patient has a significant perfusion issue?

<p>Ventilation may still appear normal (A)</p> Signup and view all the answers

What can significantly alter the imaging time in a perfusion study?

<p>Amount of isotope administered (D)</p> Signup and view all the answers

For evaluating particulate deposition, which lung disorders are typically observed?

<p>Obstructive lung disorders (A)</p> Signup and view all the answers

What is the biological half-life of xenon as described?

<p>30 seconds (B)</p> Signup and view all the answers

Why is patient positioning crucial before administering the ventilation process?

<p>To guarantee the lungs are visible within the camera's field of view (A)</p> Signup and view all the answers

What should be the expected appearance of the left lung during a normal ventilation scan?

<p>A shadow from the heart creating a rounded appearance (C)</p> Signup and view all the answers

What is the characteristic gamma energy level for xenon used in lung scans?

<p>81 KeV (B)</p> Signup and view all the answers

Which position is ideally preferred for the patient during the scanning process?

<p>Supine position (C)</p> Signup and view all the answers

What is the primary purpose of using a lead shielded container in this procedure?

<p>To prevent radiation exposure (B)</p> Signup and view all the answers

What is a common result indicative of an abnormal ventilation scan?

<p>Decreased activity in certain areas (A)</p> Signup and view all the answers

How long should radioactive materials typically be stored before disposal?

<p>Ten half-lives (B)</p> Signup and view all the answers

How long should the mask remain on during the xenon lung scan?

<p>1 minute (C)</p> Signup and view all the answers

What imaging orientation is not typically performed during ventilation imaging?

<p>Upside down (A)</p> Signup and view all the answers

In the context of nuclear medicine, what does a physical half-life of 5.3 days imply?

<p>Long-term radiation exposure risk (C)</p> Signup and view all the answers

What occurs during the 'wash out' phase of the lung scan?

<p>The lungs begin to empty (C)</p> Signup and view all the answers

What could cause decreased activity in the lungs during imaging?

<p>Poor venting of the lung (D)</p> Signup and view all the answers

Why is it preferable to conduct ventilation imaging before perfusion imaging?

<p>Counts in the lungs are lower for ventilation (B)</p> Signup and view all the answers

What ensures effective visualization during a lung scan?

<p>Clear instructions to the patient (C)</p> Signup and view all the answers

What issue might arise if a patient swallows a lot of contaminated saliva during the procedure?

<p>Interference with image quality (D)</p> Signup and view all the answers

What does a ventilation scan typically show in cases of pulmonary embolism?

<p>Normal ventilation and abnormal perfusion (C)</p> Signup and view all the answers

What is a common visual artifact found in the imaging process?

<p>Stomach uptake (B)</p> Signup and view all the answers

What is one common challenge faced during the xenon administration process?

<p>Gas escaping due to improper mask fit (D)</p> Signup and view all the answers

What technological device is utilized to survey radioactive materials before disposal?

<p>GM survey meter (B)</p> Signup and view all the answers

What range of activity in the lungs should be expected during a normal xenon scan?

<p>Uniform and symmetric wash in and wash out (D)</p> Signup and view all the answers

What happens if the oxygen flow is inadequate during the ventilation process?

<p>The majority of the isotope escapes (D)</p> Signup and view all the answers

What is the role of the isotope marked on the patient during preparation?

<p>To outline the correct positioning for imaging (B)</p> Signup and view all the answers

What is considered low gamma energy according to the information provided?

<p>Below 150 Kev (A)</p> Signup and view all the answers

Which of the following might be visualized in addition to the lungs during imaging?

<p>Trachea and bronchi (B)</p> Signup and view all the answers

What effect do ventilation and perfusion studies typically aim to highlight?

<p>Mismatch areas (D)</p> Signup and view all the answers

What is an acceptable practice in nuclear medicine regarding image presentation?

<p>Masking out unnecessary areas (B)</p> Signup and view all the answers

During the imaging process, what is an important step to minimize unwanted results?

<p>Asking the patient to expel saliva (B)</p> Signup and view all the answers

What condition may cause a significant decrease in ventilation and slight decrease in perfusion?

<p>Bacterial pneumonia (C)</p> Signup and view all the answers

What indicates fatty liver prevalent in certain individuals?

<p>High liver retention with isotopes (C)</p> Signup and view all the answers

What may be indicated if one lung shows poor presentation in imaging?

<p>Partial airway obstruction (D)</p> Signup and view all the answers

Which isotopes are commonly designed to target the lungs?

<p>Xenon (D)</p> Signup and view all the answers

How long is the biological half-life of xenon in ventilation imaging?

<p>30 seconds (A)</p> Signup and view all the answers

What is the typical dose range for aerosol used in lung studies?

<p>25 to 40 milliliters (D)</p> Signup and view all the answers

What is a recommended patient position during aerosol ventilation?

<p>Either upright or supine (D)</p> Signup and view all the answers

What is the significant advantage of using DTA aerosol over xenon for imaging?

<p>Longer stay in lungs (A)</p> Signup and view all the answers

What body part is most commonly targeted by isotopes during lung studies?

<p>Heart (C)</p> Signup and view all the answers

What should be avoided during the inhalation procedure of aerosol?

<p>Exhaling through the nose (B)</p> Signup and view all the answers

How does oxygen contribute to the aerosolization process during imaging?

<p>It helps mix with the DTA to create a mist (B)</p> Signup and view all the answers

In patients with certain lung conditions, what is an important logistical consideration?

<p>Ensure they remain upright during scanning (B)</p> Signup and view all the answers

What can high liver uptake during lung studies signify?

<p>Fatty liver disease (C)</p> Signup and view all the answers

What is a common weight limit for tables used in lung scans?

<p>350 to 400 pounds (A)</p> Signup and view all the answers

What might a reverse mismatch in lung scans indicate?

<p>Pneumonia or atelectasis (B)</p> Signup and view all the answers

During a lung scan, how does scanning in an upright position affect the process?

<p>It takes longer but can still produce good images. (B)</p> Signup and view all the answers

What is the primary benefit of administering a lower dose of particles to a patient?

<p>It benefits the patient by minimizing exposure. (B)</p> Signup and view all the answers

What type of lung defect is characterized by wedge-shaped areas in the lungs?

<p>Pulmonary embolism (D)</p> Signup and view all the answers

In which scenario should a chest X-ray be performed within one hour?

<p>When the patient exhibits severe symptoms. (A)</p> Signup and view all the answers

What is the most common reason patients visit a nuclear medicine technologist?

<p>Chest pain or shortness of breath (C)</p> Signup and view all the answers

What is the likelihood of pulmonary embolism at the low probability level?

<p>10 to 19% (B)</p> Signup and view all the answers

What is the preferred method of injection for the radiopharmaceutical?

<p>Straight stick injection. (B)</p> Signup and view all the answers

How many large mismatch segmental perfusion defects indicate a high probability of pulmonary embolism?

<p>Two or more (C)</p> Signup and view all the answers

What procedure is commonly performed in conjunction with a lung scan?

<p>Chest X-ray (D)</p> Signup and view all the answers

What is the consequence of injecting the radiopharmaceutical through tubing?

<p>Potential loss of dosage due to stickiness. (D)</p> Signup and view all the answers

In what situations might a lung scan still be performed despite advancements in CT technology?

<p>For highly claustrophobic or allergic patients (C)</p> Signup and view all the answers

What typically correlates with high probability of pulmonary embolism in lung scans?

<p>Two large mismatch segmental defects (C)</p> Signup and view all the answers

What is indicated by a striped sign in lung imaging?

<p>Possible emphysema or COPD (A)</p> Signup and view all the answers

What is the typical dose range for TEC Museum 99 M macro aggregated albumin?

<p>2 to 6 milliliters. (C)</p> Signup and view all the answers

Why is it critical to use a negatively pressurized room when administering xenon gas?

<p>To prevent xenon contamination in the external environment (B)</p> Signup and view all the answers

What is a significant risk associated with the longer half-life of xenon gas?

<p>Increased contamination of the procedure room (D)</p> Signup and view all the answers

What is the role of the physician when interpreting lung scan data?

<p>Making the final diagnosis (C)</p> Signup and view all the answers

Why should patients be maintained in a supine position during the perfusion study?

<p>To ensure uniform distribution of the radiopharmaceutical. (A)</p> Signup and view all the answers

What percentage of the population is affected by subsegment defects?

<p>7% (B)</p> Signup and view all the answers

What could happen if blood is drawn into the syringe before injecting the radiopharmaceutical?

<p>Formation of blood clots in the syringe. (B)</p> Signup and view all the answers

Which component helps contain excess xenon during the procedure?

<p>Xenon charcoal trap (A)</p> Signup and view all the answers

What result is considered normal after administering the radiopharmaceutical?

<p>Homogeneous uptake throughout the lungs. (D)</p> Signup and view all the answers

What characterizes intermediate probability for pulmonary embolism?

<p>20 to 79% likelihood (B)</p> Signup and view all the answers

What should a patient do during the 'wash in' phase when ventilation with xenon gas is initiated?

<p>Take a deep breath and hold it (D)</p> Signup and view all the answers

Which lung condition correlates with a negative chest x-ray and matched ventilation defects?

<p>Atelectasis (C)</p> Signup and view all the answers

During which phase is dynamic imaging taken while using xenon gas for lung scans?

<p>Equilibrium phase (D)</p> Signup and view all the answers

What should be done if intravenous administration is the only option for injection?

<p>Ensure to flush the tubing thoroughly after injection. (C)</p> Signup and view all the answers

How long does the entire process of the xenon lung scan typically take?

<p>60 seconds (A)</p> Signup and view all the answers

What might be the impact of a patient's claustrophobia during lung scanning?

<p>Upright scanning may be necessary. (C)</p> Signup and view all the answers

What is the primary imaging concern if a patient has a pulmonary embolism?

<p>Difficulty in diagnosing due to hot clots. (C)</p> Signup and view all the answers

What is a disadvantage of using xenon gas for lung imaging compared to CT scans?

<p>Longer imaging time (B)</p> Signup and view all the answers

What defines a normal result in the context of pulmonary embolism assessment?

<p>No perfusion defects with normal chest x-ray (B)</p> Signup and view all the answers

How should the patient be positioned following the injection to promote proper blood flow?

<p>Supine with arms lifted. (A)</p> Signup and view all the answers

What is the main purpose of ventilation in nuclear medicine lung scans?

<p>To assess airflow in the lungs (A)</p> Signup and view all the answers

What is the primary purpose of asking patients to take deep breaths before injection?

<p>To enhance airflow and aid distribution in the lungs. (D)</p> Signup and view all the answers

Which type of imaging is typically performed in conjunction with the ventilation portion?

<p>Perfusion imaging. (D)</p> Signup and view all the answers

Which patient population may not be suitable for a CT scan for lung imaging?

<p>Patients with claustrophobia (A)</p> Signup and view all the answers

What flow rate is commonly set for delivering xenon gas during lung imaging?

<p>12 liters per minute (D)</p> Signup and view all the answers

What imaging method has largely replaced lung scans for diagnosing pulmonary embolism?

<p>CT imaging (B)</p> Signup and view all the answers

What is the primary treatment for a patient diagnosed with a pulmonary embolism?

<p>Blood thinners and rest (C)</p> Signup and view all the answers

Why might a physician be cautious in diagnosing a pulmonary embolism?

<p>To prevent misdiagnosis and subsequent liability (A)</p> Signup and view all the answers

What does a quantitative lung scan primarily evaluate?

<p>Blood flow percentage in lung segments (D)</p> Signup and view all the answers

In the case of a quantitative lung scan, why is the posterior perfusion view considered most important?

<p>It minimizes the effects of gravity on blood flow measurements (C)</p> Signup and view all the answers

What is necessary to make a proper diagnosis using imaging for pulmonary embolism?

<p>A chest x-ray (A)</p> Signup and view all the answers

What is the minimum number of particles needed for effective imaging in a quantitative lung scan?

<p>75,000 particles (D)</p> Signup and view all the answers

Which condition makes results from a quantitative lung study indeterminate?

<p>Greater than 75% of the lung zone having obstructive lung disease (D)</p> Signup and view all the answers

What imaging technique is most commonly used for assessing airflow in the lungs?

<p>Ventilation scan (B)</p> Signup and view all the answers

Why do patients need to remove items like jewelry during a quantitative lung scan?

<p>To prevent artifacts in imaging results (A)</p> Signup and view all the answers

What would indicate a normal ventilation scan?

<p>Clear triangular wedges in the perfusion (D)</p> Signup and view all the answers

What is the typical post-treatment requirement for patients treated with blood thinners for pulmonary embolism?

<p>Continued blood thinner use after discharge (D)</p> Signup and view all the answers

What should the positioning of patients be during the injection for a quantitative lung scan?

<p>Supine to prevent gravitational effects (D)</p> Signup and view all the answers

Which of the following lung scan views are usually included in a complete assessment?

<p>Lateral, anterior, and posterior views (D)</p> Signup and view all the answers

Which imaging result indicates areas of concern for lung perfusion?

<p>Triangular wedges indicating abnormalities (A)</p> Signup and view all the answers

Flashcards

VQ Scan

A nuclear medicine procedure used to evaluate lung function by looking at both ventilation and perfusion. It helps diagnose pulmonary embolism (PE), a serious blood clot in the lungs.

Ventilation Study

A component of a VQ scan that assesses air movement in the lungs. It involves inhaling a radioactive gas (Xenon 133) and imaging its distribution.

Perfusion Study

A component of a VQ scan evaluating blood flow to the lungs. It involves injecting a radioactive substance (technetium-99m macroaggregated albumin) into the veins, allowing for visualization of its distribution.

ISM (Inhaled Technetium-99m DTPA Aerosol)

An alternative to the traditional perfusion study using technetium-99m macroaggregated albumin. A radioactive aerosol is inhaled to evaluate blood flow to the lungs. For this, technetium-99m DTPA (diethylenetriaminepentaacetic acid) is used.

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VQ Scan for Pulmonary Embolism

A type of VQ scan used to determine the likelihood of a pulmonary embolism. It is considered positive if there are significant differences between ventilation and perfusion, indicating a potential blockage in the lungs.

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High Probability VQ Scan

A VQ scan showing significant mismatches between ventilation and perfusion, suggesting a high chance of a blood clot in the lungs.

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Low Probability VQ Scan

A VQ scan showing only minor or no mismatches between ventilation and perfusion, suggesting a low chance of a blood clot in the lungs.

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Quantitative Lung Scan

A type of lung scan measuring lung function more precisely. It can measure how much gas is exchanged in different areas of the lungs.

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Physical Half-Life

The time it takes for the amount of a radioactive substance to halve due to radioactive decay.

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Biological Half-Life

The time it takes for the concentration of a substance in the body to reduce by half. This is influenced by factors like metabolism and excretion.

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Ventilation Phase

The initial phase of a VQ scan where xenon gas is inhaled to assess lung function.

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Wash-in

The process of xenon gas flowing into and filling the lungs.

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Equilibrium

The state where the xenon gas has reached a steady concentration in the lungs.

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Wash-out

The process of xenon gas being exhaled from the lungs.

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Normal Ventilation Results

The ideal outcome of a ventilation study where xenon gas flows in, equilibrates, and flows out evenly in both lungs.

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Abnormal Ventilation Results

Areas of decreased xenon activity during a ventilation study, indicating potential lung problems.

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Cardiac Notch

The shadow-like appearance in the left lung during a ventilation study caused by the heart overlapping the lung tissue.

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Perfusion Phase

The second part of a VQ scan that examines how well blood flows through the lungs.

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Pulmonary Embolism (PE)

A blockage in the pulmonary arteries, often detected by a VQ scan.

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Ventilation-Perfusion Mismatch

A mismatch between normal airflow and abnormally reduced blood flow in the lungs, indicating a possible PE.

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Patient Positioning

Positioning the patient properly before a VQ scan to ensure the lungs are within the field of view of the camera.

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Radioactive Marking

The use of a radioactive isotope to mark the patient's body before a VQ scan.

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Xenon Administration

The process of administering xenon gas to the patient during the ventilation phase of a VQ scan.

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Ventilation Scan

A type of nuclear medicine test that uses radioactive gas to assess lung ventilation

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Supine Position

The position where the patient lies face up

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Lead Shielded Container

A container used to store radioactive materials, typically made of lead to shield radiation.

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Half-Life

The time it takes for a radioactive substance to decay to half its original amount.

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GM Survey Meter

An instrument used to measure radiation levels.

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Anterior-Posterior (AP) Images

Images taken from the front and back of the patient.

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Lateral Images

Images taken from the side of the patient.

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Oblique Images

Images taken at a 45-degree angle from the front and back

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Perfusion Scan

A nuclear medicine test that assesses blood flow to the lungs

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Air Trapping

Air trapped in the lungs due to inadequate ventilation

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Contaminated Saliva Swallowing

Excessive swallowing of contaminated saliva during a ventilation scan

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Masking

The process of removing or masking unwanted areas on an image

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Trachea and Bronchi Visualization

Visualizing the trachea and bronchi in a ventilation scan

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Areas of Decreased Activity

Areas of decreased activity on a ventilation scan, indicating poor ventilation

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Ventilation/Perfusion Lung Scan

A medical procedure used to diagnose pulmonary embolism (blood clot in the lungs).

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Xenon Ventilation Lung Scan

A type of lung scan that uses xenon gas to assess ventilation (how well air moves in and out of the lungs).

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Negatively Pressurized Room

A specialized room with exhaust system designed for using xenon gas in lung scans.

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Xenon Gas

A gas used in ventilation lung scans to assess how effectively air moves through the lungs.

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Xenon Charcoal Trap

A substance that traps xenon gas, preventing contamination in the room.

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Ventilation System

A device that delivers a controlled amount of xenon gas to the patient during a ventilation scan.

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Mask

A mask worn by the patient during the xenon ventilation scan to help them breathe the gas.

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Wash In Phase

The process of infusing xenon gas into the patient's lungs, filling them with the gas.

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Equilibrium Phase

The phase of the scan where xenon gas is allowed to equilibrate or reach a stable level within the lungs.

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Wash Out Phase

The process of observing the clearance or removal of xenon gas from the lungs after the wash-in phase.

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Disadvantage of Xenon Gas

A potential disadvantage of using xenon gas as it requires a specific room setup and careful handling due to its radioactive nature.

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Correlation

The process of comparing images from different imaging modalities (like chest X-rays or ultrasound) to confirm the results of lung scans.

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Claustrophobia

A condition where someone has a strong fear of enclosed spaces.

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Ventilation Study in Pulmonary Embolism

A lung ventilation study usually shows normal results in cases of pulmonary embolism but with mismatched areas of activity in perfusion, meaning blood flow.

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Xenon Ventilation Study

A specific type of lung ventilation study that uses a radioactive gas to assess lung function.

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Lung Perfusion Study

The process of using a radioactive material to assess blood flow through the lungs.

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Ventilation Study: Obstruction

An obstruction in the airways, such as a collapsed lung or blocked bronchus, will result in a ventilation study showing missing or reduced ventilation distal to the obstruction.

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Ventilation Study: Obstructive Lung Disease

A lung ventilation study may show clumps or areas of high particle content in patients with obstructive lung diseases, such as COPD and emphysema.

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Lung Perfusion Study: Pulmonary Embolism

Indicates an area of the lung where blood flow is reduced or blocked, sometimes appearing as a triangular shape.

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Importance of Lung Perfusion Study

The most important part of a lung scan, revealing potential blood clots.

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Ventilation Study: Accelerated Clearance

A lung ventilation study showing an accelerated clearance of aerosols may be a sign of chronic interstitial lung disease, inflammation, or pneumonia.

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Technetium-99m Macroaggregated Albumin (MAA)

The radioactive material used in a lung perfusion study, consisting of tiny particles that get trapped in the lung.

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Lung Scan Indications: Pulmonary Embolism

The use of lung ventilation and perfusion studies is generally indicated for diagnosing pulmonary embolism, a condition where blood clots form in the lungs.

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Lung Scan Resolution

Lung scans are not as detailed as CT scans, so they are not the primary tool for diagnosing other respiratory conditions.

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Lung Scan History

The use of lung scans has historically been focused on ruling out pulmonary embolism.

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Lung Perfusion Study Applications

Lung perfusion studies can be used to assess the overall blood flow in the lungs in various situations, including chest pain, shortness of breath, and lung cancer evaluation.

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Lung Perfusion Study Contraindication: Pulmonary Hypertension

Individuals with pulmonary hypertension may be at risk for breathing problems during a lung perfusion study due to the potential obstruction caused by the radioactive particles.

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Lung Perfusion Study Modification: Reduced MAA Dose

To minimize the risk of airway obstruction during a perfusion study in patients with pulmonary hypertension, a reduced dose of the radioactive material (MAA) is administered.

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COPD and Emphysema in Ventilation Scan

A lung condition characterized by uneven distribution of air and delayed washout in the lower lobes, especially during expiration. This is often accompanied by matching perfusion defects.

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Bacterial Pneumonia in Ventilation Scan

A type of pneumonia presenting with significantly reduced ventilation and slightly decreased perfusion in the affected lung area.

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Fatty Liver in Ventilation Scan

High liver uptake of the radiotracer during lung ventilation imaging, often associated with alcoholics or morbidly obese individuals. This suggests an abnormal liver function.

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Tracer Uptake in Other Organs (Ventilation Imaging)

The radiotracers used in ventilation imaging are designed to primarily target specific organs, like the lungs, but can also be taken up by other organs to varying degrees, depending on the specific isotope and its properties. This is a normal finding and can be observed in organs like the liver, gallbladder, and bowel.

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Alcoholism in Ventilation Scan

High liver uptake in ventilation imaging, especially when it's not a common finding, can suggest a failing liver due to alcoholism.

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Atelelectasis or Bronchial Obstruction in Ventilation Scan

When one lung appears poorly ventilated in a ventilation scan, it could indicate a collapsed lung (atelectasis) or a blockage in the airway (bronchial obstruction).

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Xenon Ventilation Scan

The most common method of ventilation imaging is a ventilation scan with xenon gas, which is inert and readily diffuses into the alveoli. Xenon has a short biological half-life, meaning it clears quickly from the body.

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Aerosol Ventilation (DTA) Scan

A secondary method of ventilation imaging using an aerosol of technetium 99m diethylenetriamine pentaacetic acid (DTA) to visualize lung ventilation. This technique utilizes a higher energy radiotracer than xenon and has a longer half-life, allowing for repeated imaging.

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DTA Aerosol Delivery

The process of delivering the DTA aerosol to the patient for ventilation imaging involves using an aerosol nebulizer, similar to an inhaler, where oxygen mixes with the liquid DTA to create a mist that the patient inhales.

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Importance of Tight Seal (DTA Aerosol)

The patient should make a tight seal with their lips around the mouthpiece of the aerosol nebulizer during the ventilation procedure to ensure the aerosol enters the lungs efficiently and minimize escape of the mist.

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Breathing Technique (DTA Aerosol)

The patient should breathe slowly and deeply, taking exaggerated breaths, to ensure the DTA aerosol reaches all areas of the lungs effectively during the ventilation scan.

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Ventilation Scan Duration (DTA Aerosol)

The duration of the ventilation scan with the DTA aerosol is usually around 5 minutes.

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Oxygen Flow Rate (DTA Aerosol)

The oxygen flow rate during the DTA aerosol ventilation scan is typically between 10-12 liters per minute to create a strong airflow and effectively mix the DTA in the nebulizer.

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Patient Positioning (DTA Aerosol)

Patients can be positioned upright or lying flat during the DTA aerosol ventilation scan based on their comfort level and lung condition. Many patients find upright positioning easier, especially if they have respiratory issues.

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Ventilation Scan in Upright Position

The DTA ventilation scan is usually performed upright if the patient needs to be scanned in that position for other imaging procedures, ensuring consistent results and patient well-being.

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Table Weight Limit

The maximum weight that a table can bear.

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Upright Lung Scan

A position where the patient stands upright during a lung scan.

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Perfusion Defect

A wedge-shaped area of reduced blood flow in the lungs, potentially indicating a pulmonary embolism.

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Matched Ventilation Perfusion Defect

A pattern of ventilation matching a perfusion defect, suggesting a possible blockage in the lungs.

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Mismatched Ventilation Perfusion Defect

A pattern of ventilation not matching a perfusion defect, which can indicate other lung issues like pneumonia or atelectasis.

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Pipe Head Protocol

A classification of pulmonary embolism likelihood based on VQ scan results and chest x-ray.

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No Probability of Pulmonary Embolism

Indicates a very low likelihood of a pulmonary embolism. VQ scan shows no perfusion defects, and chest x-ray is normal.

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Low Probability Pulmonary Embolism

Indicating a low probability of a pulmonary embolism. VQ scan may show minor perfusion defects, but chest x-ray is normal.

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Intermediate Probability Pulmonary Embolism

Indicating a moderate probability of a pulmonary embolism. VQ scan shows significant mismatch between ventilation and perfusion.

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High Probability Pulmonary Embolism

Indicating a high likelihood of a pulmonary embolism. VQ scan demonstrates marked mismatches, indicating a significant blockage.

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Probability of Pulmonary Embolism

The degree of uncertainty associated with a diagnosis of PE, based on factors like VQ scan results and chest x-ray findings.

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Physician's Diagnosis of Pulmonary Embolism

The doctor's decision-making process in diagnosing Pulmonary Embolism based on the analysis of various factors.

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Technologist's Role in Pulmonary Embolism Diagnosis

The role of the technologist in providing valuable information regarding VQ scans, aiding the radiologist in diagnosing.

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What is a VQ scan?

The ratio of ventilation (airflow) to perfusion (blood flow) in the lungs.

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What is a ventilation study?

A type of VQ scan where a radioactive gas, like xenon, is inhaled and its movement is tracked.

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What is a perfusion study?

A type of VQ scan where a radioactive substance is injected into the veins and its movement is tracked.

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What is a high probability VQ scan?

A VQ scan result that suggests a high likelihood of a pulmonary embolism.

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What is a low probability VQ scan?

A VQ scan result that suggests a low likelihood of a pulmonary embolism.

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What is a quantitative lung scan?

A type of lung scan that measures how much gas is exchanged in different areas of the lungs.

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What is half-life?

The time it takes for the amount of a radioactive substance to decrease by half.

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What is the typical right lung to left lung ventilation/perfusion ratio?

The normal ratio of ventilation to perfusion in the right lung compared to the left lung.

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What is the supine position?

The position in which the patient lies face-up for imaging.

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What are the four quadrants of the lungs?

The normal location of ventilation and perfusion in a VQ scan.

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Activity and Acquisition Time

The amount and duration of the radioactive substance used in a VQ scan determines how long it takes to collect the necessary images. Using less activity (lower dose) extends the imaging time.

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VQ Scan for Lung Disorders

A VQ scan is used to diagnose and evaluate lung disorders, including pneumonia (lung infection) and Chronic Obstructive Pulmonary Disease (COPD), a chronic lung disease.

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Chest X-ray in VQ Scan

The VQ scan requires a chest X-ray to confirm the results and compare the images. This helps doctors rule out other possible reasons for the patient's symptoms.

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Pre-Injection Preparation for VQ Scan

The patient must take deep breaths and cough before injecting the radiopharmaceutical. This helps clear the airways and improve the distribution of the radioactive material in the lungs.

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Ventilation Study in VQ Scan

The ventilation portion of the VQ scan involves inhalation of Xenon gas or a DTPA aerosol. Both visualize how air is being circulated through the lungs.

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Perfusion Study in VQ Scan

The perfusion portion of the VQ scan involves injecting a radioactive substance called technetium-99m macroaggregated albumin (MRA) into a vein. This shows how blood flows through the lungs.

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Direct Injection in VQ Scan

A straight stick injection is preferred for administering the MRA, as it minimizes the risk of the radiopharmaceutical getting trapped in the tubing.

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Tubing Injection for VQ Scan

Injecting MRA through tubing can be done in emergencies if no other access point is available. However, thorough flushing afterward is crucial to ensure the patient receives the full dose.

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Supine Position for VQ Scan

The patient should be placed in the supine position (lying flat on their back) during the perfusion portion of the VQ scan. This minimizes the risk of MRA concentrating in the lower lobes of the lungs.

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Avoiding Blood Mixing in VQ Scan

Drawing blood into the syringe while administering MRA can create small blood clots, which might hinder the results and even be a health risk for the patient.

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Normal VQ Scan Results

Normal VQ scan results show a homogeneous uptake of the radiopharmaceutical in the lungs, with minor attenuation due to structures like bones, breasts, or the heart.

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Upright Position for VQ Scan

Scanning in an upright position can be an option for large patients as it allows better lung visualization. However, this is not the routine procedure.

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MRA Properties in VQ Scan

The MRA used in the perfusion study is a radioactive substance that releases energy at 140 kilovolts (kV) with a half-life of six hours. This means its radioactivity decreases by half every six hours.

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MRA Dose in VQ Scan

The dose of MRA given to the patient varies depending on their size and weight. Typically, it ranges from 2 to 6 millicuries (mCi).

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Ventilation Images

A series of images taken of the lungs during a ventilation study to assess airflow throughout the lungs.

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Perfusion Images

A series of images taken of the lungs during a perfusion study to evaluate blood flow to the lungs.

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Wedge-shaped Areas

Abnormal pattern seen in perfusion lung scans, indicating a possible pulmonary embolism.

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Nuclear Medicine

The use of radioactive substances in medicine to diagnose and monitor diseases.

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Inhaled Technetium-99m DTPA Aerosol

A type of VQ scan where the patient breathes in a radioactive aerosol to evaluate blood flow to the lungs.

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Study Notes

Learning Objectives

  • Differentiate Xenon 133 gas ventilation from ISM 99m DTA aerosol ventilation techniques.
  • Describe the perfusion lung scan process for pulmonary embolism (PE).
  • Explain the combined ventilation and perfusion process for VQ scans.
  • Differentiate between low and high probability VQ scans for PE.
  • Describe the process for a quantitative lung scan.

Ventilation Scan

  • VQ scan assesses ventilation and perfusion (blood flow).
  • "VQ" originally had quantitative data for perfusion; now separate.
  • Primary purpose: rule out PE, often a medical emergency.
  • Performed as a stat procedure; sometimes scheduled.

Ventilation Methods

  • Xenon Gas:
    • Used in a negatively pressurized room with exhaust to prevent contamination.
    • Gas can escape easily.
    • Administered via mask; 10-20 millicuries (mCi).
    • Room walls and surfaces can be contaminated due to escaping gas.
    • Long physical half-life (5.3 days); short biological half-life (30 seconds) impacts contamination risks.
    • Charcoal filter traps escaping gas.
    • Tight patient seal required to prevent contamination.
    • Gas flow is generally 12 liters per minute.
    • Patient takes deep breath for initial Xenon uptake.
    • Dynamic images during wash-in, equilibrium, and wash-out phases.
    • Scan takes approximately 60 seconds.
    • Proper patient positioning vital for lung visibility. Markers used on top of shoulders, left and right, and slightly below lungs.
  • DTA Aerosol:
    • Higher energy (140 keV) than Xenon.
    • Liquid radiopharmaceutical vaporized into an aerosol.
    • Administered via tight-seal mask and oxygen flow (10-12 liters/minute).
    • Typically lasts 5 minutes, allowing for re-administration if needed.
    • Patient can be positioned upright or supine; upright for better view, sometimes useful for larger patients.

Perfusion Scan

  • Injects TEC-99m-macroaggregated albumin (MRA; radiopharmaceutical) into vein.
  • Straight stick injection preferred to avoid tubing contamination.
  • Administered 2-6 millicuries (mCi).
  • Patient placed in supine position.
  • Requires 75,000-700,000 particles for optimal viewing, avoiding clots when possible.
  • Images acquired for each acquisition view (anterior, posterior, lateral, oblique).
  • Acquisition views are matched with corresponding ventilation view.
  • Important to have patient take deep breaths and cough to distribute the isotope through the lungs.

Quantitative Lung Scan

  • Measures lung function.
  • Usually a perfusion-only scan.
  • Injects MRA radiopharmaceutical.
  • Patient in supine position (to prevent gravity effects).
  • Regions of interest (ROIs) drawn on images.
  • Software quantifies relative blood flow to different lung segments.
  • Normal ratio: Approximately 55% right lung, 45% left lung (left lung often slightly lower due to heart overlay).

Results Interpretation (for all scans)

  • Normal Results: Uniform blood flow and vent activity throughout lungs.
  • Abnormal Results (Ventilation): In cases of pulmonary embolism, ventilation should be normal; perfusion will show abnormalities. (low flow areas)
  • Abnormal Results (Perfusion): Triangular-shaped defects (wedges), decreased blood flow. These indicate likely PE.
  • Other Results:
    • COPD/Emphysema: patchy uptake, clumping.
    • Bacterial pneumonia: ventilation and perfusion decreased.
    • Fatty liver (alcoholism, obesity): isotope uptake in liver.
    • Collapsed lung: missing or very weak vent activity on one side.
    • Bronchial obstruction, less ventilation distal to the obstruction.

Diagnosis Probability

  • Low (0-10%), moderate (20-79%) or high (>80% probability): Based on extent/location of perfusion defects in combination with other radiographic evidence (X-ray, etc.).

Importance of Correlation

  • Ventilation and perfusion scans must be interpreted together with a chest X-ray. Chest X-ray is extremely important for correlation

Additional Precautions for All Scans

  • Maintain tight seals.
  • Ensure patient's head and lungs remain in the proper position during scans for ventilation and perfusion.
  • Shield radiopharmaceuticals appropriately.
  • Follow departmental protocols for isotope disposal.

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