Pulmonary Drug Delivery Systems Lecture
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Questions and Answers

What is the main purpose of pulmonary drug delivery?

  • Depositing inhaled drugs in lower airways (correct)
  • Treating chronic obstructive pulmonary disease (COPD)
  • Delivering drugs for systemic activity
  • Treating pulmonary infections

    • Which condition is NOT mentioned as a local effect that can be treated using pulmonary drug delivery?

  • Asthma
  • Diabetes (correct)
  • Cystic fibrosis
  • Pulmonary infections

    • Why is the lung considered a route for delivering drugs having systemic activity?

  • Large surface area and blood supply (correct)
  • Improved drug formulation
  • Preventing local effects of drugs
  • Thick barrier between lung and systemic circulation

    • Which type of drugs can be delivered via the airways for systemic effect?

    <p>Vaccines and growth hormone</p> Signup and view all the answers

    What is the role of effective drug delivery to the lungs?

    <p>Dependent on the formulation, delivery device, and patient</p> Signup and view all the answers

    Why is pulmonary drug delivery suitable for treating cystic fibrosis?

    <p>Local effects are not effective for cystic fibrosis</p> Signup and view all the answers

    What is the advantage of pulmonary drug delivery in terms of minimizing side effects?

    <p>Delivers the required dose of drug to the site of action</p> Signup and view all the answers

    What is a disadvantage of some pulmonary drug delivery systems?

    <p>Deposition of drug to lower airways may be impeded by mucus</p> Signup and view all the answers

    Which region does the lower respiratory tract comprise?

    <p>Respiratory bronchioles and alveolar regions</p> Signup and view all the answers

    What happens to insoluble particles deposited in the conducting airways?

    <p>They are swallowed</p> Signup and view all the answers

    What is an essential requirement for pulmonary dosage forms to ensure pharmacological action at specific sites?

    <p>Delivering drug to the site of action</p> Signup and view all the answers

    What is dependent on particle size in terms of deposition within the respiratory tract?

    <p>The site of the deposited particle/droplet</p> Signup and view all the answers

    What does the upper respiratory tract include?

    <p>Trachea and bronchi</p> Signup and view all the answers

    What is the main purpose of pulmonary drug delivery?

    <p>Delivering drugs to the alveoli for systemic effect</p> Signup and view all the answers

    Which of the following conditions is NOT mentioned as a local effect that can be treated using pulmonary drug delivery?

    <p>Pulmonary hypertension</p> Signup and view all the answers

    Why is the lung considered a route for delivering drugs having systemic activity?

    <p>The presence of large surface area and excellent blood supply in the alveoli</p> Signup and view all the answers

    What is dependent on effective drug delivery to the lungs?

    <p>The formulation, delivery device, and patient</p> Signup and view all the answers

    What is an essential requirement for pulmonary dosage forms to ensure pharmacological action at specific sites?

    <p>Targeting to specific regions in the lower airways</p> Signup and view all the answers

    What happens to insoluble particles deposited in the conducting airways?

    <p>They may cause blockages and impair airflow</p> Signup and view all the answers

    In the context of pulmonary drug delivery, which factor affects the deposition of particles/droplets within the respiratory tract?

    <p>The effect of humidity on particle size</p> Signup and view all the answers

    What is the role of the conducting airways in the context of pulmonary drug delivery?

    <p>To trap particles on the walls and facilitate their removal from the lungs</p> Signup and view all the answers

    Which advantage of pulmonary drug delivery is NOT mentioned in the given text?

    <p>Uniform distribution of drug to all lung regions</p> Signup and view all the answers

    What is a potential problem related to the physical stability of pharmaceutical aerosols in pulmonary drug delivery?

    <p>Challenges in maintaining the stability of aerosolized drugs</p> Signup and view all the answers

    Which anatomical feature contributes to making some pulmonary drug delivery systems conspicuous in use?

    <p>Bulky nature of some delivery systems</p> Signup and view all the answers

    What is an essential requirement for pulmonary dosage forms to ensure pharmacological action at specific sites within the respiratory tract?

    <p>Deposition of particles/droplets to the required site</p> Signup and view all the answers

    What does the lower respiratory tract comprise, according to Dr. RAGHAD AL NUSS?

    <p>Trachea, bronchi, bronchioles, and alveolar regions</p> Signup and view all the answers

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