Pulmonary Drug Delivery Systems Lecture

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Questions and Answers

What is the main purpose of pulmonary drug delivery?

  • Depositing inhaled drugs in lower airways (correct)
  • Treating chronic obstructive pulmonary disease (COPD)
  • Delivering drugs for systemic activity
  • Treating pulmonary infections

Which condition is NOT mentioned as a local effect that can be treated using pulmonary drug delivery?

  • Asthma
  • Diabetes (correct)
  • Cystic fibrosis
  • Pulmonary infections

Why is the lung considered a route for delivering drugs having systemic activity?

  • Large surface area and blood supply (correct)
  • Improved drug formulation
  • Preventing local effects of drugs
  • Thick barrier between lung and systemic circulation

Which type of drugs can be delivered via the airways for systemic effect?

<p>Vaccines and growth hormone (A)</p> Signup and view all the answers

What is the role of effective drug delivery to the lungs?

<p>Dependent on the formulation, delivery device, and patient (B)</p> Signup and view all the answers

Why is pulmonary drug delivery suitable for treating cystic fibrosis?

<p>Local effects are not effective for cystic fibrosis (A)</p> Signup and view all the answers

What is the advantage of pulmonary drug delivery in terms of minimizing side effects?

<p>Delivers the required dose of drug to the site of action (A)</p> Signup and view all the answers

What is a disadvantage of some pulmonary drug delivery systems?

<p>Deposition of drug to lower airways may be impeded by mucus (D)</p> Signup and view all the answers

Which region does the lower respiratory tract comprise?

<p>Respiratory bronchioles and alveolar regions (C)</p> Signup and view all the answers

What happens to insoluble particles deposited in the conducting airways?

<p>They are swallowed (A)</p> Signup and view all the answers

What is an essential requirement for pulmonary dosage forms to ensure pharmacological action at specific sites?

<p>Delivering drug to the site of action (C)</p> Signup and view all the answers

What is dependent on particle size in terms of deposition within the respiratory tract?

<p>The site of the deposited particle/droplet (A)</p> Signup and view all the answers

What does the upper respiratory tract include?

<p>Trachea and bronchi (B)</p> Signup and view all the answers

What is the main purpose of pulmonary drug delivery?

<p>Delivering drugs to the alveoli for systemic effect (D)</p> Signup and view all the answers

Which of the following conditions is NOT mentioned as a local effect that can be treated using pulmonary drug delivery?

<p>Pulmonary hypertension (A)</p> Signup and view all the answers

Why is the lung considered a route for delivering drugs having systemic activity?

<p>The presence of large surface area and excellent blood supply in the alveoli (A)</p> Signup and view all the answers

What is dependent on effective drug delivery to the lungs?

<p>The formulation, delivery device, and patient (A)</p> Signup and view all the answers

What is an essential requirement for pulmonary dosage forms to ensure pharmacological action at specific sites?

<p>Targeting to specific regions in the lower airways (C)</p> Signup and view all the answers

What happens to insoluble particles deposited in the conducting airways?

<p>They may cause blockages and impair airflow (B)</p> Signup and view all the answers

In the context of pulmonary drug delivery, which factor affects the deposition of particles/droplets within the respiratory tract?

<p>The effect of humidity on particle size (A)</p> Signup and view all the answers

What is the role of the conducting airways in the context of pulmonary drug delivery?

<p>To trap particles on the walls and facilitate their removal from the lungs (A)</p> Signup and view all the answers

Which advantage of pulmonary drug delivery is NOT mentioned in the given text?

<p>Uniform distribution of drug to all lung regions (D)</p> Signup and view all the answers

What is a potential problem related to the physical stability of pharmaceutical aerosols in pulmonary drug delivery?

<p>Challenges in maintaining the stability of aerosolized drugs (B)</p> Signup and view all the answers

Which anatomical feature contributes to making some pulmonary drug delivery systems conspicuous in use?

<p>Bulky nature of some delivery systems (D)</p> Signup and view all the answers

What is an essential requirement for pulmonary dosage forms to ensure pharmacological action at specific sites within the respiratory tract?

<p>Deposition of particles/droplets to the required site (B)</p> Signup and view all the answers

What does the lower respiratory tract comprise, according to Dr. RAGHAD AL NUSS?

<p>Trachea, bronchi, bronchioles, and alveolar regions (B)</p> Signup and view all the answers

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