Public Health & Preventive Medicine PMBc303 Lecture 2
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Public Health & Preventive Medicine PMBc303 Lecture 2

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Questions and Answers

What defines a pandemic in terms of its geographical impact?

  • It occurs worldwide. (correct)
  • It is constant within a geographic region.
  • It is a larger than expected number of cases in a local area.
  • It happens sporadically without concentration.
  • Which of the following correctly describes a point-source outbreak?

  • Is characterized by infections that stop and start intermittently.
  • Results from a toxin exposure over several weeks.
  • Involves a single source with prolonged exposure.
  • Occurs when individuals are exposed for a short time period. (correct)
  • Which term best describes an epidemic that affects a specific geographic region at a constant, low level?

  • Pandemic
  • Epidemic
  • Endemic (correct)
  • Sporadic
  • How can epidemic patterns be visualized for analysis?

    <p>By constructing a histogram known as an epidemic curve.</p> Signup and view all the answers

    Which of the following describes an intermittent common-source outbreak?

    <p>Infections occur sporadically and are followed by periods of no cases.</p> Signup and view all the answers

    Which factor is NOT typically used to classify epidemic patterns?

    <p>Type of pathogen involved.</p> Signup and view all the answers

    In a continuous common-source outbreak, how does the epidemic curve typically appear?

    <p>Showing a flat, wide peak reflecting prolonged exposure.</p> Signup and view all the answers

    What characterizes epidemic outbreaks that are defined as sporadic?

    <p>They have no discernible pattern in occurrence.</p> Signup and view all the answers

    What is a characteristic of a propagated source outbreak?

    <p>Usually involves person-to-person contact</p> Signup and view all the answers

    In terms of incidence, which of the following statements is correct?

    <p>It refers to the rate of new cases over a specified time period</p> Signup and view all the answers

    How can a vehicle-borne transmission occur in a propagated epidemic?

    <p>By sharing contaminated food items</p> Signup and view all the answers

    What distinguishes a common-source outbreak from a propagated outbreak?

    <p>Propagated outbreaks involve an ongoing spread through the population</p> Signup and view all the answers

    What is the primary transmission mechanism identified by John Snow in the Broad Street cholera epidemic?

    <p>Fecal-oral transmission</p> Signup and view all the answers

    Which of the following factors can affect the susceptibility of a host during an epidemic?

    <p>Health status and immune competence of the individual</p> Signup and view all the answers

    Which of the following factors is considered when identifying a susceptible host in epidemiology?

    <p>Genetic predisposition</p> Signup and view all the answers

    Which transmission mechanism is specifically referred to in the propagation of the Ebola virus?

    <p>Person-to-person contact through infected body fluids</p> Signup and view all the answers

    How did John Snow demonstrate the inoculation of cholera in susceptible hosts during the outbreak?

    <p>By tracing drinking water sources and mapping cases</p> Signup and view all the answers

    What is the primary measure indicated by prevalence rates?

    <p>The total number of cases present in a population at a specific time</p> Signup and view all the answers

    Which classification category would the Broad Street cholera epidemic fall under?

    <p>Epidemic disease</p> Signup and view all the answers

    What defines a continuous common-source outbreak?

    <p>Has a single exposure that distributes over an extended time period</p> Signup and view all the answers

    In the context of the epidemiologic triangle, which component is represented by the River Thames in the cholera outbreak?

    <p>Environmental factor</p> Signup and view all the answers

    What is the significance of the removal of the pump handle in Snow's investigation?

    <p>It was the first instance of disease prevention through environmental change.</p> Signup and view all the answers

    Which of the following does NOT belong to the categories of epidemic patterns?

    <p>Evolving epidemic</p> Signup and view all the answers

    What is the primary objective of epidemiologists when studying disease spread?

    <p>To control and limit the spread of pathogens</p> Signup and view all the answers

    Study Notes

    Public Health & Preventive Medicine (PMBc303)

    • Course: Public Health & Preventive Medicine
    • Course code: PMBc303
    • Academic year: 2024/2025
    • Professor: Reham Elkased

    Lecture 2: Introduction to Epidemiology

    • Topic: Health
    • Topic: Public health
    • Topic: Epidemiology

    Epidemiology: The Science of Disease

    • Definition: A branch of public health that studies disease and its spread in populations (human and non-human). Its aim is to limit pathogens and other negative health issues.
    • Greek Origin: Epi - upon, demos - people, ology - study
    • Epidemiologists: Often called "Disease Detectives," they investigate the cause of disease, identify those at risk, and find ways to stop its spread and prevent future occurrences.

    Pioneers of Epidemiology: John Snow

    • 1854 Broad Street Cholera Epidemic: Snow observed that cholera was spread by contaminated water from the River Thames, downstream from London.
    • Fecal-oral route of transmission: Water contaminated with sewage and human waste.
    • Water pump investigation: he mapped cholera cases and linked infections to a specific water pump on Broad Street.
    • Public health response: Local officials removed the pump handle, controlling the epidemic.
    • First known public health response to an epidemic.

    Epidemiology Triangle

    • Agent: The cause of the disease (e.g., bacteria, virus). Factors include pathogenicity and dose.
    • Host: The person who can get the disease. Factors include susceptibility, genetic composition, nutrition, and immunity.
    • Environment: The surroundings and external conditions that support disease transmission (e.g., climate, insects, crowding).
    • Time: Incubation period and duration of illness; time period from infection to epidemic threshold.

    Chain of Infection

    • Infectious Agents: Bacteria, Fungi, Parasites, Viruses
    • Reservoirs: Sources where these agents live, grow, and reproduce (e.g., humans, animals, environment).
    • Portal of Entry: How the agent enters the susceptible host (e.g., respiratory tract).
    • Portal of Exit: How the agent leaves the reservoir (e.g., respiratory tract, skin).
    • Modes of Transmission: How the agent moves from reservoir to host (e.g., direct contact, airborne, vector-borne).

    Human Reservoir: Carriers

    • Classifications of carriers:
      • Passive carriers (healthy carriers): People who never experience symptoms but can transmit the disease.
      • Active carriers: Infected individuals who may or may not show symptoms.
    • Incubatory carrier - shed the microorganism during the incubation period
    • Convalescent carrier - shed the microorganism after recovery.
    • Incubation period: The time between the entry of the microorganism and the onset of symptoms.
    • Convalescent period: The time between the end of symptoms and when the microorganism is no longer present.

    Levels of Disease

    • Endemic: Constant presence or usual prevalence of a disease in a geographic area (e.g., Hepatitis A, schistosomiasis in Egypt).
    • Epidemic: Sudden increase in disease cases above the normal expectancy for a geographic area (e.g., SARS in 2003).
    • Outbreak: Same as epidemic, but in a more limited geographic region.
    • Pandemic: Epidemic that spreads over multiple countries or continents and affects a large number of people (e.g., Spanish Flu, Covid-19).
    • Sporadic: Disease that occurs infrequently and without any geographic concentration.

    Epidemic Patterns

    • Common source: Outbreak from a single source (e.g., contaminated food/water). Subtypes include point source (exposure within a short time), continuous sources (exposure over a prolonged period), and intermittent sources (exposure that is not continuous).
    • Propagated source: Direct person-to-person contact, vehicle-borne, or vector-borne outbreaks (e.g., Hepatitis B, Yellow Fever).

    Measures of Disease Frequency

    • Incidence: Proportion of people who develop a condition during a specific time period(number of new cases divided by the population).
    • Prevalence: Proportion of people who have a condition at or during a specific time (number of cases divided by the population).

    Additional Topics

    • Portal of exit
    • Susceptible host

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    Description

    Dive into the fundamentals of epidemiology with this quiz from PMBc303. Explore the science behind disease spread, the role of epidemiologists, and the historical context provided by pioneers like John Snow. Test your knowledge and understanding of public health and disease prevention strategies.

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