PTSD Diagnostic Criteria and Prevalence

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Questions and Answers

What is one of the main criticisms of the DSM-5 criterion for PTSD?

  • It requires a life-threatening event for diagnosis.
  • It focuses too much on male experiences.
  • It confuses PTSD with severe anxiety disorders.
  • It can be faked for financial gain. (correct)

Which demographic group is most significantly more likely to develop PTSD after a traumatic event?

  • Racial/ethnic minorities.
  • Women who experience trauma. (correct)
  • Civilians living in war zones.
  • Men who have served in the military.

What is the lifetime prevalence of PTSD in the general population?

  • 10-15%
  • 1-3% (correct)
  • 12-15%
  • 5-7%

How does culture influence the prevalence of PTSD in different racial/ethnic groups?

<p>Minority groups seek treatment less often than whites. (D)</p> Signup and view all the answers

What is the duration limit for symptoms of Acute Stress Disorder (ASD)?

<p>Lasts no longer than 4 weeks. (A)</p> Signup and view all the answers

What percentage of PTSD patients typically do not respond adequately to psychotherapy?

<p>40-60% (D)</p> Signup and view all the answers

Which of the following is not mentioned as a potential benefit of using MDMA in psychotherapy for PTSD?

<p>Inducing hallucinations (C)</p> Signup and view all the answers

What characterizes psychedelic drugs in the context of PTSD treatment?

<p>They assist emotional and cognitive processing. (A)</p> Signup and view all the answers

In what year was MDMA-assisted psychotherapy designated as a breakthrough therapy for PTSD?

<p>2017 (B)</p> Signup and view all the answers

Why might traditional psychotherapy be insufficient for some PTSD patients?

<p>Patients are often emotionally challenged during exposure therapy. (D)</p> Signup and view all the answers

What are the primary cannabinoids studied for their effects on PTSD?

<p>Tetrahydrocannabinol (THC) and Cannabidiol (CBD) (B)</p> Signup and view all the answers

How do cannabinoids primarily interact with the body in relation to PTSD?

<p>Through the endocannabinoid system (B)</p> Signup and view all the answers

What effects has nabilone shown in PTSD patients according to the studies mentioned?

<p>Significant improvement in distressing dreams and global well-being (B)</p> Signup and view all the answers

What is a potential risk associated with the use of cannabinoids in susceptible individuals?

<p>Development of psychotic disorders (A)</p> Signup and view all the answers

How do classical psychedelics contribute to therapy, despite their potential to induce difficult experiences?

<p>They can be part of the therapeutic process. (A)</p> Signup and view all the answers

What is the role of Big 5 Openness in MDMA-assisted psychotherapy?

<p>It moderates the relationship between MDMA treatment and PTSD symptom reduction. (B)</p> Signup and view all the answers

Which brain regions are affected by MDMA during treatment?

<p>The amygdala and frontal cortex. (B)</p> Signup and view all the answers

What was the outcome for patients receiving MDMA in the study involving 12 treatment-resistant patients with PTSD?

<p>83% of patients no longer met PTSD criteria. (C)</p> Signup and view all the answers

What effect does MDMA have on oxytocin levels?

<p>It increases oxytocin levels, which may enhance interpersonal trust. (D)</p> Signup and view all the answers

How does the psychotherapy process unfold during MDMA sessions?

<p>Therapists allow the client's own process to unfold nondirectively. (D)</p> Signup and view all the answers

Flashcards

Post-traumatic stress disorder (PTSD)

A mental health disorder that develops after a person experiences a traumatic event and is characterized by intrusive memories, avoidance behaviors, negative thoughts and feelings, and increased arousal.

Substance-assisted psychotherapy

A type of therapy that involves using psychedelic drugs in conjunction with traditional talk therapy to help people process traumatic experiences.

Acute stress disorder (ASD)

A short-term reaction to a stressful event characterized by similar symptoms to PTSD, however, the duration is much shorter (within 1 month of trauma exposure and lasts no longer than 4 weeks).

Emotional and Cognitive Processing

The ability of a person to process and understand their emotions, thoughts, and experiences in a healthy way.

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Adjustment disorder

A disorder characterized by emotional and behavioral symptoms (depression, anxiety, or antisocial behavior) that arise within 3 months of a stressful event.

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Psychedelic Drug

A drug that can induce a wide range of psychological, cognitive, emotional, and physical effects, including altered perceptions of self and reality.

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Therapeutic Alliance

This refers to the ability to work together effectively with another person, especially in a therapy setting.

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Prevalence of PTSD

The prevalence of PTSD is higher among groups who are at risk of experiencing severe trauma. For example, 12-33% of civilians living in war zones experience PTSD.

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Gender differences in PTSD

Women are more likely to develop PTSD after experiencing trauma, potentially due to experiencing triggers more often, especially sexual abuse, and facing greater stigma, limiting social support.

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Post-Traumatic Stress Disorder (PTSD)

A state of anxiety and fear related to past traumatic experiences. It can be a short-term response to a trauma, or it can become a more chronic, persistent condition.

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MDMA's Impact on Social Interaction

MDMA enhances emotional empathy, prosocial behavior, and feelings of closeness, leading to increased openness and trust.

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MDMA-assisted Psychotherapy

MDMA-assisted therapy shows promise in producing lasting personality changes, improving PTSD symptoms and potentially increasing openness to new experiences.

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MDMA's Brain Impact

By activating the frontal cortex and attenuating amygdala activity, MDMA helps regulate emotional responses, potentially reducing PTSD symptoms.

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MDMA and Oxytocin

MDMA increases oxytocin, a hormone associated with trust and social bonding, which may explain its effects on social interaction.

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MDMA & Social Reward Learning

MDMA, even after its immediate effects wear off, can reopen a key window for social learning, making it possible for individuals to form new, positive social connections.

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Ayahuasca

A type of plant that contains the psychoactive compound DMT and has been used for centuries by indigenous Amazonian people for medicinal, spiritual, and other reasons. It is also being investigated for its potential in treating PTSD.

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Cannabinoids

A group of chemicals found in cannabis, including THC and CBD, that interact with the endocannabinoid system in the body. They are being researched for their potential in relieving PTSD symptoms.

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Endocannabinoid System

The body's internal system that regulates mood, stress, and memory. It is impacted by cannabinoids, which may explain the potential of these compounds in treating PTSD.

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EMDR (Eye Movement Desensitization and Reprocessing)

A type of exposure therapy that involves bilateral stimulation (like eye movements) while processing traumatic memories. The goal is to help individuals reduce the emotional impact of traumatic memories.

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Nabilone

A synthetic cannabinoid that mimics THC and has shown promise in reducing PTSD symptoms, particularly nightmares and sleep problems, in clinical trials.

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Study Notes

PTSD Diagnostic Criteria and Prevalence

  • Post-traumatic stress disorder (PTSD) is a persistent anxiety disorder triggered by a traumatic event (actual/threatened death, serious injury, or sexual violence).
  • It's classified as a trauma-and-stressor-related disorder, distinguishing it from other anxiety or dissociative disorders. The traumatic experience is a defining factor in the diagnosis.
  • PTSD symptoms fall into four categories: intrusive symptoms (re-experiencing the trauma), avoidance, negative alterations in mood and cognition, and hyperarousal/hypervigilance.
  • PTSD symptoms can develop even if the stressor is not life-threatening, such as witnessing a stressful event.
  • Lifetime prevalence of PTSD is estimated at 1-3% of the general population, but is higher for groups with a higher risk of experiencing severe trauma (e.g., 12-33% for civilians in war zones, 10% for rescue workers).

Gender Differences in PTSD

  • Women are significantly more likely than men to develop PTSD after a traumatic experience (2.4 times more).
  • Possible contributing factors include differences in the nature of experienced trauma (e.g., sexual abuse vs war) and the associated stigma surrounding different types of trauma.
  • Cultural factors and socioeconomic status can also contribute to differing rates of help-seeking among different demographic groups.

Acute Stress Disorder (ASD)

  • ASD is a short-term psychological and physical response to severe trauma.
  • Symptoms are similar to PTSD, but last no longer than 4 weeks, arising within 1 month of the trauma.
  • Individuals with ASD have a high risk of developing PTSD symptoms in the subsequent months.

Avoidance and Dissociation

  • Avoidance coping strategies after trauma often do not improve psychological health and can increase PTSD risk.
  • Dissociation is a coping mechanism for detaching from trauma, which is a risk factor for developing PTSD.
  • Dissociation may be an avoidant strategy for managing painful memories.
  • People who dissociate during or just before a traumatic experience are more likely to develop PTSD.

Conditioning Theory

  • Classical conditioning can explain PTSD symptoms. Trauma (unconditioned stimulus) becomes associated with the place and time of the trauma (conditioned stimulus), eliciting conditioned fear responses. Avoidance behavior reinforces this association.

Emotional Processing Theory

  • Severe trauma leads to unique memory representations and associations, overriding previous positive associations related to a cue.
  • Severe trauma can significantly change an individual's beliefs about themselves and the world.

Mental Defeat

  • Mental defeat involves a victim mentality, negative processing of trauma, and a perceived lack of control over the outcome.
  • Negative beliefs about self and the world resulting from trauma can maintain the disorder.

PTSD Treatment

  • Exposure therapies (e.g., imaginal flooding, VR) aim to extinguish trauma-related fear by confronting trauma-related cues.
  • Cognitive restructuring therapies assist patients with challenging and replacing dysfunctional thoughts and beliefs about the world.
  • EMDR (eye movement desensitization and reprocessing) is an exposure-based therapy that has been controversial but has shown efficacy in some studies.
  • Psychological debriefing is a structured intervention that aims to prevent PTSD in the immediate aftermath of trauma, but its efficacy is debated.

Biological Factors

  • Elevated cortisol levels, hippocampus size, and amygdala activity are sometimes observed in PTSD patients.
  • Genetic factors, and environmental factors and social factors can increase risk of PTSD.

Psychological Vulnerability Factors

  • Factors that can increase vulnerability to PTSD include pre-existing anxiety, depression, or psychological disorders, low intelligence, and a tendency toward personal responsibility for events or misfortunes of others around them.
  • Early childhood experiences, particularly separation from parents, or unstable family life contribute to greater risk and can change biological response to stress.

Treatments of Dissociative Disorders

  • Treating dissociative disorders often involves psychodynamic and insight-oriented therapies focused on uncovering, releasing, and working through past trauma.
  • These therapies aim to integrate different personality fragments/identities/states into a single coherent self and to resolve dissociative defenses.
  • Standardized treatment protocols for dissociative disorders are not common, leading to difficulty in assessing therapy effectiveness.

Dissociative Disorders

  • Dissociative disorders include a variety of syndromes that alter consciousness and impact memory and identity.
  • Conditions include amnesia, fugue, dissociative identity disorder, and depersonalization/derealization disorder.
  • Dissociative Disorders are not always triggered or caused by trauma, but they can be associated with it. These conditions can be difficult to diagnose accurately and the criteria for diagnosis can be subjective.

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