Podcast
Questions and Answers
Under what condition do tricyclic antidepressants have an effect?
Under what condition do tricyclic antidepressants have an effect?
- In patients with generalized anxiety disorder
- Only when OCD is comorbid with depression (correct)
- When used alone without any other treatments
- During exposure therapy sessions
What should be considered as a second-line pharmacological treatment after not responding to at least two SSRIs?
What should be considered as a second-line pharmacological treatment after not responding to at least two SSRIs?
- Paroxetine
- Sertraline
- Fluoxetine
- Clomipramine (correct)
Which treatment is considered a last resort for OCD?
Which treatment is considered a last resort for OCD?
- Cognitive Behavioral Therapy
- Neurosurgery (correct)
- Pharmacological treatments
- Standard psychotherapy
What does the inhibitory learning model suggest about fear associations during exposure therapy?
What does the inhibitory learning model suggest about fear associations during exposure therapy?
What evidence is there regarding cingulotomy as a treatment for OCD?
What evidence is there regarding cingulotomy as a treatment for OCD?
How does the amygdala behave during fear conditioning and extinction learning?
How does the amygdala behave during fear conditioning and extinction learning?
What can cause conditioned fear to return after exposure therapy?
What can cause conditioned fear to return after exposure therapy?
What is one potential risk after undergoing exposure therapy?
What is one potential risk after undergoing exposure therapy?
What can cause conditioned fear to return after extinction?
What can cause conditioned fear to return after extinction?
What is a key characteristic of individuals with anxiety disorders regarding exposure therapy?
What is a key characteristic of individuals with anxiety disorders regarding exposure therapy?
Which of the following best describes the difference between habituation-based models and inhibitory learning models in exposure therapy?
Which of the following best describes the difference between habituation-based models and inhibitory learning models in exposure therapy?
What is the role of expectancy violation in exposure therapy?
What is the role of expectancy violation in exposure therapy?
What factor does NOT significantly influence fear expressed at follow-up assessments?
What factor does NOT significantly influence fear expressed at follow-up assessments?
What happens during rapid reacquisition of conditioned responses (CR)?
What happens during rapid reacquisition of conditioned responses (CR)?
What is a common outcome for people who do not respond well to exposure-based therapies?
What is a common outcome for people who do not respond well to exposure-based therapies?
Which strategy can help optimize inhibitory learning during exposure therapy?
Which strategy can help optimize inhibitory learning during exposure therapy?
What is deepened extinction primarily aimed at achieving?
What is deepened extinction primarily aimed at achieving?
How does occasional reinforced extinction enhance treatment outcomes?
How does occasional reinforced extinction enhance treatment outcomes?
What effect does the removal of safety signals have during exposure therapy?
What effect does the removal of safety signals have during exposure therapy?
What is variability in exposure therapy meant to accomplish?
What is variability in exposure therapy meant to accomplish?
Which scenario best exemplifies deepened extinction for panic disorder and agoraphobia?
Which scenario best exemplifies deepened extinction for panic disorder and agoraphobia?
What is the primary focus of the expectancy violation model in exposure therapy?
What is the primary focus of the expectancy violation model in exposure therapy?
Why is the occasional reinforcement during extinction training beneficial?
Why is the occasional reinforcement during extinction training beneficial?
How does the approach of interoceptive conditioning differ from standard exposure therapy?
How does the approach of interoceptive conditioning differ from standard exposure therapy?
What approach is commonly agreed upon regarding safety behaviors in exposure therapy?
What approach is commonly agreed upon regarding safety behaviors in exposure therapy?
What is the result of cognitive interventions prior to exposure in the expectancy violation model?
What is the result of cognitive interventions prior to exposure in the expectancy violation model?
What is a potential consequence of maintaining safety signals during exposure therapy?
What is a potential consequence of maintaining safety signals during exposure therapy?
In the context of social anxiety, how should a patient frame their predictions regarding expected outcomes?
In the context of social anxiety, how should a patient frame their predictions regarding expected outcomes?
What does the expectancy violation model state about the attention during exposure?
What does the expectancy violation model state about the attention during exposure?
What does the study suggest about the duration of exposure in relation to learning outcomes?
What does the study suggest about the duration of exposure in relation to learning outcomes?
How does the gradual exposure technique in the expectancy violation model function?
How does the gradual exposure technique in the expectancy violation model function?
How should patients consolidate learning after each exposure trial?
How should patients consolidate learning after each exposure trial?
What is the primary purpose of the sentence paradigm used to induce TAF?
What is the primary purpose of the sentence paradigm used to induce TAF?
How is TAF related to responsibility for harm?
How is TAF related to responsibility for harm?
What might a participant believe about a negative event after experiencing TAF?
What might a participant believe about a negative event after experiencing TAF?
Which of the following best describes the relationship between TAF and obsessional complaints?
Which of the following best describes the relationship between TAF and obsessional complaints?
What is a unique feature of moral TAF as it relates to clinical samples?
What is a unique feature of moral TAF as it relates to clinical samples?
What statistical correlation was observed in the study regarding TAF and event probability?
What statistical correlation was observed in the study regarding TAF and event probability?
In recent cognitive models, how is TAF characterized?
In recent cognitive models, how is TAF characterized?
Which factor has been found to correlate with moral TAF?
Which factor has been found to correlate with moral TAF?
What factor structure is considered optimal for TAF in clinical samples?
What factor structure is considered optimal for TAF in clinical samples?
Which disorder is NOT mentioned as being associated with Moral TAF?
Which disorder is NOT mentioned as being associated with Moral TAF?
Which belief is specifically NOT reported as being common among OCD patients?
Which belief is specifically NOT reported as being common among OCD patients?
What has been found about the prevalence of TAF in individuals with Generalized Anxiety Disorder (GAD)?
What has been found about the prevalence of TAF in individuals with Generalized Anxiety Disorder (GAD)?
What is implied about the role of TAF in the treatment of OCD?
What is implied about the role of TAF in the treatment of OCD?
What statement reflects a possible misconception about TAF?
What statement reflects a possible misconception about TAF?
Based on the evidence, what can be said about the specific type of TAF related to positive outcomes?
Based on the evidence, what can be said about the specific type of TAF related to positive outcomes?
In which specific case might TAF need to be addressed in treatment?
In which specific case might TAF need to be addressed in treatment?
Flashcards
Exposure Therapy
Exposure Therapy
A type of psychotherapy where individuals are repeatedly exposed to their fears in a safe environment without the actual threat occurring. This helps to extinguish the fear response by creating a new association between the feared stimuli and safety.
Inhibitory Learning Model of Extinction
Inhibitory Learning Model of Extinction
A model that explains how exposure therapy works by suggesting that the original fear association isn't erased, but a new, inhibitory association is learned. This means the feared stimulus now predicts safety, not danger.
Amygdala and Medial PFC in Fear Learning
Amygdala and Medial PFC in Fear Learning
The part of the brain involved in processing fear and emotions. During fear conditioning, the amygdala becomes highly active. However, during extinction learning, the medial PFC helps suppress the amygdala's activity, reducing fear.
Spontaneous Recovery
Spontaneous Recovery
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Context-Dependent Relapse
Context-Dependent Relapse
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Second-Line Pharmacological Treatments for OCD
Second-Line Pharmacological Treatments for OCD
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Cingulotomy
Cingulotomy
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Rapid Reacquisition of Fear
Rapid Reacquisition of Fear
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Extinction
Extinction
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Inhibitory Learning
Inhibitory Learning
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Habituation
Habituation
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Deficits in Inhibitory Learning and Anxiety Disorders
Deficits in Inhibitory Learning and Anxiety Disorders
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Expectancy Violation
Expectancy Violation
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Expectancy Violation
Expectancy Violation
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Expectancy Violation Approach to Exposure Therapy
Expectancy Violation Approach to Exposure Therapy
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Expectancy-Based Exposure Therapy
Expectancy-Based Exposure Therapy
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Memory Consolidation in Expectancy Violation
Memory Consolidation in Expectancy Violation
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Salient Cue in Expectancy Violation
Salient Cue in Expectancy Violation
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Task-Specific Learning in Expectancy Violation
Task-Specific Learning in Expectancy Violation
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Cognitive Interventions and Expectancy Violation
Cognitive Interventions and Expectancy Violation
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Gradual Exposure in Expectancy Violation
Gradual Exposure in Expectancy Violation
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Deepened Extinction
Deepened Extinction
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Occasional Reinforced Extinction
Occasional Reinforced Extinction
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Removal of Safety Signals
Removal of Safety Signals
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Variability
Variability
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Interoceptive Exposure
Interoceptive Exposure
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Post-Exposure Cognitive Interventions
Post-Exposure Cognitive Interventions
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Thought-Action Fusion (TAF)
Thought-Action Fusion (TAF)
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Likelihood-TAF
Likelihood-TAF
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Moral-TAF
Moral-TAF
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Catastrophic Misinterpretation
Catastrophic Misinterpretation
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Obsessive Psychopathology
Obsessive Psychopathology
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Cognitive Behavioral Therapy (CBT)
Cognitive Behavioral Therapy (CBT)
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Likelihood-Other TAF
Likelihood-Other TAF
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Positive TAF
Positive TAF
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Likelihood-Self TAF
Likelihood-Self TAF
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Inert TAF
Inert TAF
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Harm Avoidance TAF
Harm Avoidance TAF
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Study Notes
Obsessive-Compulsive Disorder (OCD)
- OCD is a disorder characterized by obsessions (disturbing, intrusive thoughts) or compulsions (ritualistic behaviors) or both.
- Common obsessions include harming oneself or others, contamination fears, accidents, or unacceptable sexual thoughts.
- Doubting, indecision, and a need for order can lead to compulsive behaviors like checking, washing, hoarding, and arranging objects in a specific way.
- Compulsions are performed to reduce anxiety stemming from obsessions.
- Ritualistic compulsions are often excessive or unreasonable.
- Magical thinking often links obsessions and compulsions: belief that certain rituals prevent harm.
- OCD rituals are usually stereotyped and rigid, often with concern over performing behaviors correctly.
DSM-5 Criteria for OCD
- Obsessions: Recurrent, unwanted thoughts, urges, or images that cause significant anxiety or distress. Individuals try to ignore or suppress these thoughts.
- Compulsions: Repetitive behaviors (e.g., hand washing, checking) or mental acts (e.g., praying, counting) performed in response to an obsession or according to rigid rules. These behaviors aim to prevent distress or a dreaded event. Actions are usually not realistically connected to the feared outcome and are excessive.
Symptoms and Subtypes
- Symptom onset is usually gradual in adolescence or adulthood following a stressful event.
- Obsessions can center on themes like sex, violence, or religion.
- Common OCD subtypes include:
- Early-onset
- Hoarding
- "Just right."
- Tic-related (current or past history of tic disorder)
- Scrupulosity (religious or moral obsessions)
- High rates of comorbidity often occur with OCD, particularly with other anxiety disorders, mood disorders, ADHD, and body dysmorphic disorder.
Diagnosis and Prevalence
- OCD symptoms are often a common manifestation of anxiety in childhood.
- The lifetime prevalence of OCD is about 2.5%.
- Women are slightly more often affected than men.
- Cultural factors can influence expression and type of OCD (e.g., obsessions in certain cultures might be aggressive or religious).
OCD-Related Disorders
- Body Dysmorphic Disorder (BDD): Preoccupation with perceived flaws in physical appearance, even when not apparent to others. This preoccupation leads to repeated appearance-checking and grooming behaviors.
- Hoarding Disorder: Persistent difficulty discarding or parting with possessions, regardless of their value or actual need. Leads to a cluttered living space.
Etiology of OCD
- OCD likely has a strong genetic component.
- Some neurological structures and pathways (e.g., frontal lobes, basal ganglia, and thalamus) implicated in OCD.
- Deficits in inhibitory learning and inhibitory neural processes may contribute to both poor response and the development of excessive fear and anxiety in OCD.
- Dysfunction in the serotonin system may play a role.
- Psychosocial factors (e.g., previous life events, or current social circumstances, such as relationship problems) may influence onset and expression.
Treatment
- Exposure and Response Prevention (ERP) is a common and often effective behavioral therapy. This involves facing the feared obsessions or situations, and not engaging in the associated compulsions.
- Cognitive Behavioral Therapy (CBT) is also often used, aiming to identify and challenge dysfunctional thoughts and beliefs.
- Medications such as selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed, and other second-line medications that can be useful in combination with therapy.
- Neurosurgery is reserved as a last-resort option for severe, treatment-resistant cases.
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