Questions and Answers
What is the gram stain of Pseudomonas?
gram negative rod
Where can Pseudomonas be found?
aquatic environments
What is the oxidase reaction of Pseudomonas?
oxidase positive
What is the catalase reaction of Pseudomonas?
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Patients with which disease are at risk for Pseudomonas infection because it is catalase positive?
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What color pigment does Pseudomonas produce when plated?
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Where does the blue-green pigment come from?
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What kind of odor does Pseudomonas produce?
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What type of aerobe is Pseudomonas?
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Can Pseudomonas grow in the presence of oxygen?
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Can Pseudomonas grow without oxygen?
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What is the number one cause of gram negative nosocomial pneumonia?
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What can Pseudomonas cause in cystic fibrosis patients?
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What is the most common cause of respiratory failure in cystic fibrosis patients?
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Which protein is mutated in cystic fibrosis patients, and what does it do?
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Which two groups of people are at risk for osteomyelitis from a Pseudomonas infection?
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Name four groups of people that are at risk for infection from Pseudomonas.
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Is Pseudomonas encapsulated?
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What two types of skin infections can Pseudomonas cause?
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What diseases can Pseudomonas cause?
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What is 'swimmer's ear'?
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What does exotoxin A do?
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What is the treatment for Pseudomonas?
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Study Notes
Pseudomonas Overview
- Gram-negative rod bacterium.
- Primarily found in aquatic environments.
Biochemical Properties
- Oxidase positive.
- Catalase positive.
- Obligate aerobe; can grow in the presence of oxygen but not without it.
Infections and Risk Factors
- Leading cause of gram-negative nosocomial pneumonia.
- Can cause pulmonary infections in cystic fibrosis patients, leading to respiratory failure.
- Higher risk of infection in IV drug users, diabetics, burn patients, and in-hospital patients with catheters.
Cystic Fibrosis Connection
- CFTR gene is defective in cystic fibrosis patients, impairing the pumping of chlorine ions.
Pigmentation and Odor
- Produces blue-green pigment due to pyocyanin and pyoverdin.
- Releases a fruity, grape-like odor.
Skin and Bone Infections
- Causes two types of skin infections:
- Papulo pustular folliculitis
- Ecthyma gangrenosum, presenting as black necrotic lesions.
- Associated with osteomyelitis in at-risk populations.
Ear Infections
- Known to cause otitis externa, commonly referred to as "swimmer's ear".
Toxins
- Exotoxin A ribosylates elongation factor 2, inhibiting protein synthesis and leading to cell death.
Treatment Options
- Treated with piperacillin, often combined with aminoglycosides or fluoroquinolones.
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Description
Test your knowledge on Pseudomonas with this quiz featuring key characteristics such as gram staining, oxidase reaction, and common environments. Perfect for students and professionals studying microbiology or related fields.
