Podcast
Questions and Answers
What is the action of Pseudoephedrine?
What is the action of Pseudoephedrine?
- It stimulates only alpha receptors.
- It acts as a sympathomimetic amine. (correct)
- It causes severe hypertension.
- It produces nasal congestion.
What are the uses of Pseudoephedrine?
What are the uses of Pseudoephedrine?
Symptomatic relief of nasal congestion associated with rhinitis, coryza, sinusitis, and eustachian tube congestion.
Which of the following is a contraindication for Pseudoephedrine?
Which of the following is a contraindication for Pseudoephedrine?
- Mild hypertension
- Hypersensitivity to sympathomimetic amines (correct)
- Seasonal allergies
- Common cold
In which condition should Pseudoephedrine be used cautiously?
In which condition should Pseudoephedrine be used cautiously?
The sustained-release form of Pseudoephedrine should be chewed or crushed.
The sustained-release form of Pseudoephedrine should be chewed or crushed.
Name a common adverse effect of Pseudoephedrine.
Name a common adverse effect of Pseudoephedrine.
Which of the following can interact with Pseudoephedrine?
Which of the following can interact with Pseudoephedrine?
What should be monitored when taking Pseudoephedrine?
What should be monitored when taking Pseudoephedrine?
What advice should be given to patients regarding the timing of taking Pseudoephedrine?
What advice should be given to patients regarding the timing of taking Pseudoephedrine?
What class does Pseudoephedrine belong to?
What class does Pseudoephedrine belong to?
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Study Notes
Pseudoephedrine Action
- Sympathomimetic amine that relieves respiratory tract congestion.
- Stimulates sympathetic nerve endings, activating alpha, beta1, and beta2 receptors.
- Causes vasoconstriction, resulting in increased nasal airway patency.
Pseudoephedrine Uses
- Provides symptomatic relief from nasal congestion due to rhinitis, coryza, and sinusitis.
- Effective for alleviating eustachian tube congestion.
Pseudoephedrine Contraindications
- Hypersensitivity to sympathomimetic amines.
- Severe conditions such as hypertension or coronary artery disease.
- Should not be used within 14 days of MAOIs.
- Caution in hyperthyroidism and prostatic hypertrophy.
Pseudoephedrine Cautious Use
- Use cautiously in patients with hypertension, heart disease, or renal impairment.
- Caution required in cases of acute myocardial infarction or angina.
- Not recommended for patients with closed-angle glaucoma.
- Safe usage in children under 2 years is not established.
Pseudoephedrine Administration
- Administer orally, ensuring that sustained-release forms are not chewed or crushed; they must be swallowed whole.
Pseudoephedrine Adverse Effects
- Common effects include transient stimulation, tremulousness, and difficulty with urination.
- Potential for arrhythmias, palpitations, and tachycardia.
- Other effects may involve nervousness, dizziness, headaches, sleeplessness, and numbness of extremities.
- Gastrointestinal effects including anorexia, dry mouth, nausea, and vomiting may also occur.
Pseudoephedrine Drug Interactions
- Concurrent use with other sympathomimetics may increase pressor effects and toxicity.
- MAO inhibitors can potentially lead to hypertensive crises.
- Beta-blockers may also enhance pressor effects when used together.
Pseudoephedrine Assessment and Drug Effects
- Monitor heart rate and blood pressure, especially in patients with a history of cardiac issues.
- Watch for reports of tachycardia or hypertension during treatment.
Pseudoephedrine Patient and Family Education
- Advise against taking the medication within 2 hours of bedtime due to stimulant effects.
- Discontinue and consult a prescriber if extreme restlessness or signs of sensitivity occur.
- Consult a prescriber before using other OTC medications that may contain ephedrine or other sympathomimetics that could intensify effects.
Pseudoephedrine Class
- Classified as an alpha- and beta-adrenergic receptor agonist.
- Functions primarily as a decongestant.
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