Podcast
Questions and Answers
Which of the following is true about serum prostate-specific antigen (PSA) testing?
Which of the following is true about serum prostate-specific antigen (PSA) testing?
- It is only recommended for men with a positive family history of prostate cancer.
- It is only recommended for men over the age of 70.
- It is recommended for all men as a routine screening test for prostate cancer.
- It is not recommended due to the uncertain benefits of early detection and treatment of prostate cancer. (correct)
When should men be offered a prostate-specific antigen (PSA) measurement?
When should men be offered a prostate-specific antigen (PSA) measurement?
- If they have a negative family history of prostate cancer.
- If they have a positive family history of prostate cancer.
- If they are over the age of 70.
- If they have a diagnosis of early prostate cancer that might influence treatment options. (correct)
What should be considered if a man's serum PSA level is in excess of 2.5–4ng/mL?
What should be considered if a man's serum PSA level is in excess of 2.5–4ng/mL?
- Prostate cancer screening for all men.
- Radical treatment for prostate cancer.
- Transrectal ultrasound scanning (TRUS) plus transrectal biopsies. (correct)
- No further testing is necessary.
When should transrectal ultrasound scanning (TRUS) plus transrectal biopsies be considered?
When should transrectal ultrasound scanning (TRUS) plus transrectal biopsies be considered?
What should men be informed about before undergoing a prostate-specific antigen (PSA) test?
What should men be informed about before undergoing a prostate-specific antigen (PSA) test?
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Study Notes
Prostate-Specific Antigen (PSA) Testing
- Serum PSA testing is not recommended as a screening test for prostate cancer due to its limitations.
Indications for PSA Measurement
- Men should be offered a PSA measurement if they are 50 years or older, or 45 years or older with a family history of prostate cancer.
Elevated PSA Levels
- If a man's serum PSA level is in excess of 2.5–4ng/mL, clinicians should consider the possibility of prostate cancer and further evaluation may be necessary.
Transrectal Ultrasound Scanning (TRUS) and Biopsies
- Transrectal ultrasound scanning (TRUS) plus transrectal biopsies should be considered if the PSA level is elevated or if a digital rectal examination is abnormal.
Pre-PSA Test Counseling
- Men should be informed about the potential risks and benefits of PSA testing, including the risk of false-positive results and the possibility of over-diagnosis and over-treatment, before undergoing a PSA test.
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