5 Questions
Which of the following is true about serum prostate-specific antigen (PSA) testing?
It is not recommended due to the uncertain benefits of early detection and treatment of prostate cancer.
When should men be offered a prostate-specific antigen (PSA) measurement?
If they have a diagnosis of early prostate cancer that might influence treatment options.
What should be considered if a man's serum PSA level is in excess of 2.5–4ng/mL?
Transrectal ultrasound scanning (TRUS) plus transrectal biopsies.
When should transrectal ultrasound scanning (TRUS) plus transrectal biopsies be considered?
If rectal examination is normal with no suspicion of cancer.
What should men be informed about before undergoing a prostate-specific antigen (PSA) test?
The risks of the prostate biopsy and the risks of the detection of a small prostate cancer.
Study Notes
Prostate-Specific Antigen (PSA) Testing
- Serum PSA testing is not recommended as a screening test for prostate cancer due to its limitations.
Indications for PSA Measurement
- Men should be offered a PSA measurement if they are 50 years or older, or 45 years or older with a family history of prostate cancer.
Elevated PSA Levels
- If a man's serum PSA level is in excess of 2.5–4ng/mL, clinicians should consider the possibility of prostate cancer and further evaluation may be necessary.
Transrectal Ultrasound Scanning (TRUS) and Biopsies
- Transrectal ultrasound scanning (TRUS) plus transrectal biopsies should be considered if the PSA level is elevated or if a digital rectal examination is abnormal.
Pre-PSA Test Counseling
- Men should be informed about the potential risks and benefits of PSA testing, including the risk of false-positive results and the possibility of over-diagnosis and over-treatment, before undergoing a PSA test.
Test your knowledge about serum prostate-specific antigen (PSA) and its role in the early detection of prostate cancer. Understand the benefits, risks, and uncertainties associated with the PSA test and learn about the importance of informed decision-making.
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