PSA and Risk of Prostate Cancer

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What is the treatment for an anatomic abnormality causing continuous leakage of urine with the feeling of urination?

Surgery to close or remove the fistula

What is a common symptom of ectopic position of the ureter below the sphincter?

Leakage of urine from abnormal orifices (vagina)

What is the cause of communication of the bladder with the vagina in congenital anatomic abnormalities?

Traumatic injury

What is the primary effect of distigmine bromideparasympathomimetic drug in treating anatomic abnormalities?

<p>Increasing bladder contraction</p> Signup and view all the answers

Which bacteria are commonly associated with acute pyelonephritis?

<p>E. coli and Streptococci</p> Signup and view all the answers

What is the most accurate imaging modality for detecting aggressive Gleason > 7 cancers?

<p>Multiparametric MRI</p> Signup and view all the answers

Which imaging modality is considered equivalent to PET in nodal disease detection?

<p>CT scan</p> Signup and view all the answers

At what PSA level is a bone scan recommended for detecting bone metastasis?

<p>$10$ ng/ml</p> Signup and view all the answers

Which treatment approach involves monitoring the patient and offering a palliative treatment at a future time?

<p>Active surveillance</p> Signup and view all the answers

What is the main consequence of chronic exposure to LHRH agonists?

<p>Suppressed LH and FSH secretion</p> Signup and view all the answers

At what prostate volume can prostate cancer in the peripheral zone be detected by digital rectal examination (DRE)?

<p>2.0 mL</p> Signup and view all the answers

What is the positive predictive value of a suspect DRE in patients with a PSA level up to 2 ng/mL?

<p>5-30%</p> Signup and view all the answers

Which condition is an indication for prostate biopsy according to the text?

<p>Elevated PSA due to benign prostatic hypertrophy (BPH)</p> Signup and view all the answers

Which anatomical abnormality can be detected by digital rectal examination (DRE) in about 18% of all patients with prostate cancer?

<p>Suspect DRE alone</p> Signup and view all the answers

What anatomical condition is almost exclusively associated with the elevation of prostate-specific antigen (PSA)?

<p>Prostatitis</p> Signup and view all the answers

What is the 'flare-up' phenomenon associated with the first injection?

<p>Transient rise in LH and FSH</p> Signup and view all the answers

In the clinical scenario, the patient presents with colicky pain that radiates to the groin. What anatomical abnormality is suspected?

<p>Kidney stone</p> Signup and view all the answers

What is the most likely cause of the involuntary loss of urine described in the text?

<p>Maximal urethral pressure exceeding intravesical pressure</p> Signup and view all the answers

Which combination of treatments is most likely to be recommended for a patient with urinary incontinence due to anatomic abnormalities?

<p>Surgery + hormonotherapy</p> Signup and view all the answers

What diagnostic test is most appropriate for confirming the suspected kidney stone obstruction in the clinical scenario?

<p>CT pyelography</p> Signup and view all the answers

What is the term used for the point at which ions become metastable and can initiate crystal growth and heterogeneous nucleation?

<p>Solubility product (Ksp)</p> Signup and view all the answers

Which substance in the urine prohibits crystal formation?

<p>Magnesium</p> Signup and view all the answers

Which byproduct of purine metabolism is usually found in 2-10% of stones?

<p>Uric acid</p> Signup and view all the answers

What substance decreases urinary pH, decreases urinary citrate, and increases urinary calcium excretion?

<p>Calcium</p> Signup and view all the answers

Which type of stones are related to the diet, particularly meat, dairy products, and vegetables?

<p>Phosphate stones</p> Signup and view all the answers

What is the role of the free/total PSA ratio in clinical practice?

<p>To differentiate between benign prostatic hyperplasia (BPH) and prostate cancer (PCa)</p> Signup and view all the answers

What is the purpose of a saturation repeat biopsy for prostate cancer detection?

<p>To increase the likelihood of detecting PCa missed by conventional biopsies</p> Signup and view all the answers

In what percentage of men was PCa found on biopsy when the free/total PSA ratio was less than 0.10?

<p>56%</p> Signup and view all the answers

What is the classic picture seen in a transrectal ultrasound (TRUS) for local disease?

<p>Hypo-echoic area in the peripheral zone of the prostate</p> Signup and view all the answers

What is the most likely cause of the involuntary loss of urine described in the text?

<p>Prostate cancer</p> Signup and view all the answers

In the clinical scenario, the patient presents with colicky pain that radiates to the groin. What anatomical abnormality is suspected?

<p>Kidney-ureteral stones</p> Signup and view all the answers

What anatomical condition is almost exclusively associated with the elevation of prostate-specific antigen (PSA)?

<p>Prostate cancer</p> Signup and view all the answers

What substance decreases urinary pH, decreases urinary citrate, and increases urinary calcium excretion?

<p>Plant-extras</p> Signup and view all the answers

What is the term used for the point at which ions become metastable and can initiate crystal growth and heterogeneous nucleation?

<p>Saturation repeat biopsy</p> Signup and view all the answers

Which diagnostic test is most appropriate for confirming the suspected kidney stone obstruction in the clinical scenario?

<p>$ ext{CT}$ pyelography</p> Signup and view all the answers

What anatomical abnormality can be detected by digital rectal examination (DRE) in about 18% of all patients with prostate cancer?

<p>$ ext{TURP}$</p> Signup and view all the answers

Which condition is an indication for prostate biopsy according to the text?

<p>$ ext{Hematuria}$</p> Signup and view all the answers

At what PSA level is a bone scan recommended for detecting bone metastasis?

<p>$2$ ng/mL</p> Signup and view all the answers

What is a common symptom of ectopic position of the ureter below the sphincter?

<p>Hematuria</p> Signup and view all the answers

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