Podcast
Questions and Answers
What is the function of proteoglycans in the ECM?
What is the function of proteoglycans in the ECM?
Act as tissue organizers
How are glycosaminoglycans attached to proteoglycans?
How are glycosaminoglycans attached to proteoglycans?
Covalently to a SGxG consensus motif within the protein
What are the two major families of membrane attached proteoglycans?
What are the two major families of membrane attached proteoglycans?
Syndecans and Glypicans
How do Syndecans attach to the membrane?
How do Syndecans attach to the membrane?
How are Glypicans anchored to the membrane?
How are Glypicans anchored to the membrane?
What process allows cells to change their surface features quickly?
What process allows cells to change their surface features quickly?
What is the physiological role of Heparin?
What is the physiological role of Heparin?
What is the structure of Heparin that contributes to its extended rod-like helical conformation?
What is the structure of Heparin that contributes to its extended rod-like helical conformation?
What is the function of the Glycocalyx in eukaryotic cells?
What is the function of the Glycocalyx in eukaryotic cells?
Differentiate between Glycoproteins, Proteoglycans, and Glycosphingolipids.
Differentiate between Glycoproteins, Proteoglycans, and Glycosphingolipids.
Describe the structure of Proteoglycans and how they are attached to proteins.
Describe the structure of Proteoglycans and how they are attached to proteins.
What are Syndecans and Glypicans?
What are Syndecans and Glypicans?
What is the role of aggrecan core protein in the extracellular matrix?
What is the role of aggrecan core protein in the extracellular matrix?
How are proteoglycan aggregates bound to hyaluronate?
How are proteoglycan aggregates bound to hyaluronate?
What is the function of fibronectin in the extracellular matrix?
What is the function of fibronectin in the extracellular matrix?
How do integrins interact with the extracellular matrix?
How do integrins interact with the extracellular matrix?
What percentage of mammalian proteins are glycosylated?
What percentage of mammalian proteins are glycosylated?
How are O-linked saccharides connected to proteins?
How are O-linked saccharides connected to proteins?
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