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Questions and Answers
What is the purpose of the reaction between cyanocobalamin (CN adduct) and ATP?
What is the purpose of the reaction between cyanocobalamin (CN adduct) and ATP?
- To cleave the Co-C bond and form radical species
- To form the adenylated B-12 coenzyme (correct)
- To transfer a CH3 ion to Hg, Pb, and Sn salts
- To catalyze the cleavage of the sugar-phosphate backbone of DNA
What is the function of the radical species formed from the homolytic cleavage of the Co-C bond?
What is the function of the radical species formed from the homolytic cleavage of the Co-C bond?
- To facilitate the specific uptake of iron by microorganisms
- To catalyze the cleavage of the sugar-phosphate backbone of DNA
- To transfer a CH3 ion to Hg, Pb, and Sn salts
- To participate in several enzymatically catalyzed H-transfer reactions (correct)
What is the primary function of siderophores secreted by microorganisms?
What is the primary function of siderophores secreted by microorganisms?
- To bind Fe3+ ion with high affinity and produce soluble complexes that can be taken up by the organism (correct)
- To transfer a CH3 ion to Hg, Pb, and Sn salts in aqueous solution
- To participate in several enzymatically catalyzed H-transfer reactions
- To catalyze the cleavage of the sugar-phosphate backbone of DNA
What is the primary mechanism by which bleomycin acts as an antitumor antibiotic?
What is the primary mechanism by which bleomycin acts as an antitumor antibiotic?
Which of the following is an example of a siderophore mentioned in the text?
Which of the following is an example of a siderophore mentioned in the text?
Which of the following is an example of a complex assembly mentioned in the text?
Which of the following is an example of a complex assembly mentioned in the text?
What is the main factor determining the orientation of ligand donor atoms in a metalloprotein?
What is the main factor determining the orientation of ligand donor atoms in a metalloprotein?
Which type of interactions is NOT involved in the forces affecting the folding of a polypeptide into a unique 3D structure?
Which type of interactions is NOT involved in the forces affecting the folding of a polypeptide into a unique 3D structure?
What type of structure describes the local conformation over groups of a few adjacent amino acids?
What type of structure describes the local conformation over groups of a few adjacent amino acids?
What is the role of splicing in eukaryotic gene expression?
What is the role of splicing in eukaryotic gene expression?
In a metalloprotein, what happens to the tertiary structure in the absence of bound metal?
In a metalloprotein, what happens to the tertiary structure in the absence of bound metal?
Which protein is an example of a dimer made up of two identical subunits?
Which protein is an example of a dimer made up of two identical subunits?
What contributes to the stability of the metal-binding site in metalloproteins?
What contributes to the stability of the metal-binding site in metalloproteins?
What promotes a transition from a partially folded form to a more completely folded form in some metal-binding proteins?
What promotes a transition from a partially folded form to a more completely folded form in some metal-binding proteins?
What does the removal of the Zn2+-binding site cause in zinc finger domains?
What does the removal of the Zn2+-binding site cause in zinc finger domains?
How do subunits interact with each other in proteins to form larger assemblies?
How do subunits interact with each other in proteins to form larger assemblies?
Which of the following is not one of the 20 essential amino acids that make up proteins?
Which of the following is not one of the 20 essential amino acids that make up proteins?
What is the typical configuration of the $\alpha$-carbon in amino acids found in proteins?
What is the typical configuration of the $\alpha$-carbon in amino acids found in proteins?
Which of the following amino acid side chains is NOT a common metal ion binding ligand in proteins?
Which of the following amino acid side chains is NOT a common metal ion binding ligand in proteins?
Which of the following amino acid side chains can act as a bridging ligand between two metal ions in proteins?
Which of the following amino acid side chains can act as a bridging ligand between two metal ions in proteins?
Which of the following is NOT a common secondary structure motif found in proteins?
Which of the following is NOT a common secondary structure motif found in proteins?
What is the typical configuration of the peptide bonds that link amino acids in protein chains?
What is the typical configuration of the peptide bonds that link amino acids in protein chains?
What is the function of messenger RNA (mRNA)?
What is the function of messenger RNA (mRNA)?
What is the purpose of cloning in genetic engineering?
What is the purpose of cloning in genetic engineering?
What is Vmax in enzyme kinetics?
What is Vmax in enzyme kinetics?
What are the basic structures found in RNA and DNA, respectively?
What are the basic structures found in RNA and DNA, respectively?
What is the unit comprising only a sugar and a base called?
What is the unit comprising only a sugar and a base called?
What type of RNA carries amino acids to the ribosome during protein synthesis?
What type of RNA carries amino acids to the ribosome during protein synthesis?
'Hoogsteen base pairing' is responsible for which structure?
'Hoogsteen base pairing' is responsible for which structure?
'Phosphodiester linkages' join adjacent residues to form what in nucleic acids?
'Phosphodiester linkages' join adjacent residues to form what in nucleic acids?
'Watson-Crick base-pairing interactions' are responsible for what structure in DNA?
'Watson-Crick base-pairing interactions' are responsible for what structure in DNA?
'Nucleotides' contain sugar, base, and which other group?
'Nucleotides' contain sugar, base, and which other group?
What is the characteristic feature of B-DNA, the most common form of DNA?
What is the characteristic feature of B-DNA, the most common form of DNA?
Which of the following statements about A-DNA is true?
Which of the following statements about A-DNA is true?
What is a characteristic feature of Z-DNA?
What is a characteristic feature of Z-DNA?
Which of the following statements about metal binding in nucleic acids is correct?
Which of the following statements about metal binding in nucleic acids is correct?
What is the role of magnesium ions in ATP binding and hydrolysis?
What is the role of magnesium ions in ATP binding and hydrolysis?
What is the structure of chromatin in eukaryotic cells?
What is the structure of chromatin in eukaryotic cells?
What is the significance of sulfur atoms in modified nucleosides like 4-thiouridine (s4U) in RNA?
What is the significance of sulfur atoms in modified nucleosides like 4-thiouridine (s4U) in RNA?
What is the role of prosthetic groups in metalloproteins?
What is the role of prosthetic groups in metalloproteins?
What is the metal ion present in the coenzyme cobalamin (vitamin B-12)?
What is the metal ion present in the coenzyme cobalamin (vitamin B-12)?
What is the role of chlorophylls in photosynthesis?
What is the role of chlorophylls in photosynthesis?
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