Podcast
Questions and Answers
What is the function of dolichol phosphate molecule in protein glycosylation?
What is the function of dolichol phosphate molecule in protein glycosylation?
- It acts as an enzyme to catalyze the addition of sugars to proteins.
- It is involved in recognizing the signal sequence on nascent proteins.
- It provides a hydrophobic environment for glycosylation to occur.
- It acts as a carrier molecule to transfer sugars to proteins in the ER. (correct)
What happens to N-glycosylation in mutations that disrupt the protein translocation process?
What happens to N-glycosylation in mutations that disrupt the protein translocation process?
- N-glycosylation occurs normally regardless of mutations in the translocation process.
- N-glycosylation does not occur at all in mutated proteins.
- N-glycosylation is delayed and inefficient due to improper protein folding. (correct)
- N-glycosylation is enhanced due to increased availability of sugar substrates.
Which best describes the role of Signal Recognition Particle (SRP) in protein synthesis?
Which best describes the role of Signal Recognition Particle (SRP) in protein synthesis?
- SRP helps in folding proteins correctly within the rough ER.
- SRP helps in the translocation of ribosomes from rough ER to smooth ER.
- SRP binds to the signal sequence and ribosome, aiding in targeting nascent proteins to the ER membrane. (correct)
- SRP catalyzes the cleavage of signal sequences from nascent proteins.
What is the primary function of Rough Endoplasmic Reticulum (RER) in protein synthesis?
What is the primary function of Rough Endoplasmic Reticulum (RER) in protein synthesis?
Which statement accurately describes the synthesis of integral membrane proteins?
Which statement accurately describes the synthesis of integral membrane proteins?
When SRP binds to both the signal sequence on nascent protein and ribosome, what is the next step in protein synthesis?
When SRP binds to both the signal sequence on nascent protein and ribosome, what is the next step in protein synthesis?
What is the role of the translocon in protein synthesis?
What is the role of the translocon in protein synthesis?
How do G-proteins regulate protein synthesis in the context of the text?
How do G-proteins regulate protein synthesis in the context of the text?
What is the function of SRP in protein synthesis according to the text?
What is the function of SRP in protein synthesis according to the text?
Which statement accurately describes G-proteins in protein synthesis?
Which statement accurately describes G-proteins in protein synthesis?
Which molecule is essential for N-glycosylation in protein synthesis?
Which molecule is essential for N-glycosylation in protein synthesis?
What impact would mutations affecting N-glycosylation have on protein function?
What impact would mutations affecting N-glycosylation have on protein function?
How is the dolichol phosphate molecule involved in protein glycosylation?
How is the dolichol phosphate molecule involved in protein glycosylation?
What happens once the oligosaccharide is completely assembled in glycosylation?
What happens once the oligosaccharide is completely assembled in glycosylation?
What is the consequence of mutations leading to total absence of N-glycosylation?
What is the consequence of mutations leading to total absence of N-glycosylation?
How are mutations affecting partial disruption of the glycosylation pathway in the ER different from mutations causing total absence of N-glycosylation?
How are mutations affecting partial disruption of the glycosylation pathway in the ER different from mutations causing total absence of N-glycosylation?
In protein synthesis, what role does SRP (signal recognition particle) play?
In protein synthesis, what role does SRP (signal recognition particle) play?
What happens after the dolichol-PP is flipped back across the membrane during protein glycosylation?
What happens after the dolichol-PP is flipped back across the membrane during protein glycosylation?
