Protein Synthesis and Targeting

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18 Questions

Which of the following mechanisms is responsible for transporting proteins into the nucleus?

Nuclear transport receptors

What is the primary function of the signal sequence in protein synthesis?

To target the protein to its correct destination

Which type of molecule is prevented from entering the organelle due to its impermeable membrane?

Hydrophobic molecule

What is the purpose of the nuclear localization signal in proteins?

To mark the protein for nuclear transport

Which of the following structures is involved in transporting proteins out of the ER?

Transport vesicles

What is the typical length of the signal sequence in proteins?

15-60 amino acids

Which of the following proteins plays a crucial role in the recognition process during vesicle transport?

Rab proteins

What type of bond is introduced during protein modification in the ER?

Disulfide bond

What is the primary function of SNARE proteins in vesicle transport?

To direct vesicles to the target membrane

What is the term for the process of adding a 14-sugar chain to specific amino acid residues during protein modification?

Glycosylation

What is the purpose of the recognition sequence in protein modification?

To specify the sites of glycosylation

What is the term for the proteins that facilitate vesicle-membrane binding during vesicle transport?

Tethering proteins

What determines the direction and orientation of a multi-pass transmembrane protein in the ER?

Start-Transfer-Signal

What is the function of the second signal in the integration of a multi-pass transmembrane protein into the membrane?

Causing the protein to be released into the membrane

What is the purpose of glycosylation in the ER?

To modify proteins before they leave the ER

What is the difference between Start-Transfer-Sequences and Stop-Transfer-Sequences?

Start-Transfer-Sequences are for multi-pass transmembrane proteins, while Stop-Transfer-Sequences are for single-pass transmembrane proteins

What is the result of a protein having multiple Start-Stop-Sequences in its sequence?

The protein will be integrated into the membrane multiple times

What is the primary location of protein synthesis in eukaryotic cells?

Cytosol

This quiz covers the process of protein synthesis, specifically the mechanisms of protein targeting and transport into different organelles. Learn about the roles of signal sequences, nuclear pores, and protein translocators in this crucial cellular process.

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