Protein Synthesis and Targeting

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Questions and Answers

Which of the following mechanisms is responsible for transporting proteins into the nucleus?

  • Transport vesicles
  • Nuclear transport receptors (correct)
  • Protein translocation channels
  • Protein translocators

What is the primary function of the signal sequence in protein synthesis?

  • To target the protein to its correct destination (correct)
  • To facilitate folding of the protein
  • To enhance protein stability
  • To regulate gene expression

Which type of molecule is prevented from entering the organelle due to its impermeable membrane?

  • Hydrophilic molecule
  • Hydrophobic molecule (correct)
  • Polar molecule
  • Amino acid

What is the purpose of the nuclear localization signal in proteins?

<p>To mark the protein for nuclear transport (A)</p> Signup and view all the answers

Which of the following structures is involved in transporting proteins out of the ER?

<p>Transport vesicles (A)</p> Signup and view all the answers

What is the typical length of the signal sequence in proteins?

<p>15-60 amino acids (D)</p> Signup and view all the answers

Which of the following proteins plays a crucial role in the recognition process during vesicle transport?

<p>Rab proteins (B)</p> Signup and view all the answers

What type of bond is introduced during protein modification in the ER?

<p>Disulfide bond (D)</p> Signup and view all the answers

What is the primary function of SNARE proteins in vesicle transport?

<p>To direct vesicles to the target membrane (C)</p> Signup and view all the answers

What is the term for the process of adding a 14-sugar chain to specific amino acid residues during protein modification?

<p>Glycosylation (A)</p> Signup and view all the answers

What is the purpose of the recognition sequence in protein modification?

<p>To specify the sites of glycosylation (C)</p> Signup and view all the answers

What is the term for the proteins that facilitate vesicle-membrane binding during vesicle transport?

<p>Tethering proteins (D)</p> Signup and view all the answers

What determines the direction and orientation of a multi-pass transmembrane protein in the ER?

<p>Start-Transfer-Signal (A)</p> Signup and view all the answers

What is the function of the second signal in the integration of a multi-pass transmembrane protein into the membrane?

<p>Causing the protein to be released into the membrane (A)</p> Signup and view all the answers

What is the purpose of glycosylation in the ER?

<p>To modify proteins before they leave the ER (C)</p> Signup and view all the answers

What is the difference between Start-Transfer-Sequences and Stop-Transfer-Sequences?

<p>Start-Transfer-Sequences are for multi-pass transmembrane proteins, while Stop-Transfer-Sequences are for single-pass transmembrane proteins (B)</p> Signup and view all the answers

What is the result of a protein having multiple Start-Stop-Sequences in its sequence?

<p>The protein will be integrated into the membrane multiple times (C)</p> Signup and view all the answers

What is the primary location of protein synthesis in eukaryotic cells?

<p>Cytosol (C)</p> Signup and view all the answers

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