Protein Structure: Physical and Modeling Methods Quiz
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Questions and Answers

Which method is used for de novo prediction and ab initio modeling?

  • I-TASSER (correct)
  • Swiss-Model
  • Phyre2
  • Modeller

    • Which method focuses on sorting similar structures using 'blastp'?

  • Modeller
  • I-TASSER (correct)
  • Rosetta protein folding platform
  • Swiss-Model

    • Which method utilizes the strategy assumption that protein folding is not random and considers local secondary structures, ionic interactions, and hydrophobic interactions?

  • Robetta protein folding (correct)
  • Phyre2
  • Swiss-Model
  • I-TASSER

    • Which method is associated with the Nature Methods paper by J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang in 2015?

    <p>I-TASSER (C)</p> Signup and view all the answers

    What is the strategy used for protein structure prediction in Rosetta?

    <p>Generating short peptide folds and clustering them based on energy values (D)</p> Signup and view all the answers

    What is the role of chaperons in protein folding?

    <p>Help in avoiding folding traps (B)</p> Signup and view all the answers

    What is the main feature of Intrinsic Disordered Proteins (IDPs)?

    <p>Rich in Prolines and Glycines (A)</p> Signup and view all the answers

    What is the purpose of using DALI or PDBefold in protein structure prediction?

    <p>To find similar structures for fold recognition (B)</p> Signup and view all the answers

    What is the significance of energy values in protein structure prediction?

    <p>Determining the stability of predicted structures (B)</p> Signup and view all the answers

    What is Levinthal's Paradox related to?

    <p>The role of interactions in bio-molecular reactions (D)</p> Signup and view all the answers

    What type of proteins require conformational changes and dynamic interactions with other proteins?

    <p>Intrinsic Disordered Proteins (IDPs) (A)</p> Signup and view all the answers

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