Protein Structure: Physical and Modeling Methods Quiz

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11 Questions

Which method is used for de novo prediction and ab initio modeling?

I-TASSER

Which method focuses on sorting similar structures using 'blastp'?

I-TASSER

Which method utilizes the strategy assumption that protein folding is not random and considers local secondary structures, ionic interactions, and hydrophobic interactions?

Robetta protein folding

Which method is associated with the Nature Methods paper by J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang in 2015?

I-TASSER

What is the strategy used for protein structure prediction in Rosetta?

Generating short peptide folds and clustering them based on energy values

What is the role of chaperons in protein folding?

Help in avoiding folding traps

What is the main feature of Intrinsic Disordered Proteins (IDPs)?

Rich in Prolines and Glycines

What is the purpose of using DALI or PDBefold in protein structure prediction?

To find similar structures for fold recognition

What is the significance of energy values in protein structure prediction?

Determining the stability of predicted structures

What is Levinthal's Paradox related to?

The role of interactions in bio-molecular reactions

What type of proteins require conformational changes and dynamic interactions with other proteins?

Intrinsic Disordered Proteins (IDPs)

Test your knowledge on protein structure and modeling methods including X-ray crystallography, NMR spectroscopy, cryo-electronmicroscopy, homology modeling, fold recognition, and ab initio protein folding techniques.

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