Protein Structure Overview

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Questions and Answers

What type of bond links amino acids together to form a polypeptide?

  • Hydrogen bond
  • Peptide bond (correct)
  • Ionic bond
  • Disulfide bond

Which structural level in a protein is defined by its unique sequence of amino acids?

  • Quaternary structure
  • Primary structure (correct)
  • Secondary structure
  • Tertiary structure

What happens to a protein when it denatures?

  • It forms stronger peptide bonds between its amino acids.
  • It retains its functional shape and properties.
  • It gains a more complex quaternary structure.
  • It loses its higher-level structure and function. (correct)

Which of the following is an example of a conjugated protein?

<p>A protein with a carbohydrate attached (D)</p> Signup and view all the answers

The interactions between which groups are MOST responsible for a protein's tertiary structure?

<p>R groups (A)</p> Signup and view all the answers

Flashcards

Primary Protein Structure

The linear sequence of amino acids in a protein chain.

Secondary Protein Structure

The three-dimensional shape formed by hydrogen bonds between amino acids within the polypeptide chain.

Tertiary Protein Structure

The overall three-dimensional shape of a single polypeptide chain, determined by interactions between R-groups.

Quaternary Protein Structure

The arrangement of multiple polypeptide chains (subunits) into a functional protein complex.

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Protein Denaturation

The process where a protein loses its higher-level structure (secondary, tertiary, and quaternary) due to environmental changes, rendering it inactive.

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Study Notes

Protein Structure

  • Amino acids are the building blocks of proteins
  • Proteins are made of carbon, hydrogen, nitrogen, and oxygen
  • There are 20 different amino acids, each with a unique R group
  • Peptide bonds hold amino acids together in a dehydration reaction
  • Polypeptides are chains of amino acids, with a nitrogen (N) and a carboxyl (C) terminal end
  • Conjugated proteins have a non-protein component, like an ion or carbohydrate
  • Primary structure is the sequence of amino acids
  • Secondary structure is the folding pattern of the amino acid chain (e.g., alpha-helices, beta-sheets)
  • Tertiary structure is the three-dimensional shape of a polypeptide, determined by interactions between R groups
  • Quaternary structure is the arrangement of multiple tertiary proteins
  • Denatured proteins lose their higher level structure, and therefore function
  • Proteins have various functions, including: storing amino acids, producing hormones, signaling, providing structural support, creating immunity, and catalyzing reactions (enzymatic activity)

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