Protein Structure and Function Quiz
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Questions and Answers

What is the main driving force for the folding of a globular protein?

  • Salt bridge
  • Hydrophobic effect (correct)
  • Disulfide bonds
  • pKa values
  • Which type of protein has a more complex shape, fibrous or globular?

  • Globular protein (correct)
  • Conjugated protein
  • Buffer
  • Fibrous protein
  • Which group of amino acids are considered hydrophilic?

  • Group 4: negatively-charged amino acids
  • Group 2: polar amino acids (correct)
  • Group 1: hydrophobic amino acids
  • Group 3: positively-charged amino acids
  • What is the purpose of post-translational modifications of proteins?

    <p>To alter the protein after translation</p> Signup and view all the answers

    What does pKa indicate about an acid?

    <p>Strength of the acid</p> Signup and view all the answers

    Do all 20 standard proteinogenic amino acids have ionizable side chains?

    <p>Some do and some don't</p> Signup and view all the answers

    What is the impact of the hydrophobic effect on protein folding?

    <p>It causes polar amino acids to be on the protein's exterior and nonpolar amino acids to be in the protein's interior.</p> Signup and view all the answers

    Why does isomer selection matter for pharmaceuticals?

    <p>It affects the drug's ability to bind to receptors and maximize efficacy.</p> Signup and view all the answers

    Which standard amino acid is achiral and why?

    <p>Glycine, due to its lack of a chiral center.</p> Signup and view all the answers

    Where does a protein's net charge primarily come from?

    <p>From the positively charged amino groups and negatively charged carboxyl groups in amino acids.</p> Signup and view all the answers

    What role do acetylation and phosphorylation play in chromatin remodeling?

    <p>They recruit chromatin remodeling complexes, influencing gene expression.</p> Signup and view all the answers

    How does pH impact a protein's net charge?

    <p>Higher pH leads to a more positive net charge on proteins.</p> Signup and view all the answers

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