Protein Regulation in Liver and Major Histocompatibility Complex Component Quiz
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Questions and Answers

What is the function of Pepsin?

  • Maintain albumin levels
  • Assist in vitamin A absorption
  • Digest proteins into amino acids (correct)
  • Transport thyroid hormones
  • At what pH do proteins have no net charge?

  • Acidic pH
  • Alkaline pH
  • Basic pH
  • Neutral pH (correct)
  • How can molecular size be determined?

  • Using ion-exchange chromatography
  • By ultracentrifugation (correct)
  • Through electrophoresis
  • Through mass spectrometry
  • Which protein is the second most predominant in cerebrospinal fluid?

    <p>Albumin</p> Signup and view all the answers

    What technique is used to differentiate proteins based on electrical charge?

    <p>Ion-exchange chromatography</p> Signup and view all the answers

    Which protein is primarily produced in the liver and is considered an acute phase protein?

    <p>Haptoglobin</p> Signup and view all the answers

    In which conditions would you expect to find decreased levels of haptoglobin?

    <p>Liver disease</p> Signup and view all the answers

    Which protein accounts for the majority of α-2-globulin and is found principally in the intravascular spaces?

    <p>Haptoglobin</p> Signup and view all the answers

    What protein is a light chain component of the major human leukocyte antigen (HLA) and found on the surface of most nucleated cells, with high concentrations on lymphocytes?

    <p>Beta2-Microglobulin</p> Signup and view all the answers

    Which marker can be used for acute myocardial infarction but is not specific for this condition?

    <p>Myoglobin</p> Signup and view all the answers

    In which muscle-related disorders can myoglobin levels be elevated besides acute myocardial infarction?

    <p>Cardiac and skeletal muscle disorders</p> Signup and view all the answers

    Which specimen is most commonly preferred for protein testing?

    <p>Serum</p> Signup and view all the answers

    In which body fluid can protein levels help differentiate between transudate and exudate?

    <p>CSF</p> Signup and view all the answers

    Which factor causes false decrease in protein levels in the biuret method?

    <p>High ammonia level</p> Signup and view all the answers

    Which method is preferred for rapidly estimating protein at high concentrations?

    <p>Refractometry</p> Signup and view all the answers

    What causes gamma globulins to migrate towards the cathodes during electrophoresis despite having a slightly negative charge?

    <p>Electroendosmosis</p> Signup and view all the answers

    Which condition is associated with an increase in the alpha-2 region and a decrease in albumin?

    <p>Nephrotic syndrome</p> Signup and view all the answers

    What is the main purpose of the Folin-Ciocalteu Method?

    <p>To detect proteins in low concentrations</p> Signup and view all the answers

    What is the key factor that causes false increased reference range readings in the biuret method?

    <p>High bilirubin</p> Signup and view all the answers

    What is used to complex cupric ions and prevent precipitation in the Biuret method?

    <p>Rochelle salt</p> Signup and view all the answers

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