Protein Regulation in Liver and Major Histocompatibility Complex Component Quiz

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20 Questions

What is the function of Pepsin?

Digest proteins into amino acids

At what pH do proteins have no net charge?

Neutral pH

How can molecular size be determined?

By ultracentrifugation

Which protein is the second most predominant in cerebrospinal fluid?

Albumin

What technique is used to differentiate proteins based on electrical charge?

Ion-exchange chromatography

Which protein is primarily produced in the liver and is considered an acute phase protein?

Haptoglobin

In which conditions would you expect to find decreased levels of haptoglobin?

Liver disease

Which protein accounts for the majority of α-2-globulin and is found principally in the intravascular spaces?

Haptoglobin

What protein is a light chain component of the major human leukocyte antigen (HLA) and found on the surface of most nucleated cells, with high concentrations on lymphocytes?

Beta2-Microglobulin

Which marker can be used for acute myocardial infarction but is not specific for this condition?

Myoglobin

In which muscle-related disorders can myoglobin levels be elevated besides acute myocardial infarction?

Cardiac and skeletal muscle disorders

Which specimen is most commonly preferred for protein testing?

Serum

In which body fluid can protein levels help differentiate between transudate and exudate?

CSF

Which factor causes false decrease in protein levels in the biuret method?

High ammonia level

Which method is preferred for rapidly estimating protein at high concentrations?

Refractometry

What causes gamma globulins to migrate towards the cathodes during electrophoresis despite having a slightly negative charge?

Electroendosmosis

Which condition is associated with an increase in the alpha-2 region and a decrease in albumin?

Nephrotic syndrome

What is the main purpose of the Folin-Ciocalteu Method?

To detect proteins in low concentrations

What is the key factor that causes false increased reference range readings in the biuret method?

High bilirubin

What is used to complex cupric ions and prevent precipitation in the Biuret method?

Rochelle salt

Test your knowledge of proteins produced in the liver and components of the major histocompatibility complex. This quiz covers characteristics and functions of acute phase proteins and HLA components.

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