Protein Regulation in Liver and Major Histocompatibility Complex Component Quiz
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Questions and Answers

What is the function of Pepsin?

  • Maintain albumin levels
  • Assist in vitamin A absorption
  • Digest proteins into amino acids (correct)
  • Transport thyroid hormones

At what pH do proteins have no net charge?

  • Acidic pH
  • Alkaline pH
  • Basic pH
  • Neutral pH (correct)

How can molecular size be determined?

  • Using ion-exchange chromatography
  • By ultracentrifugation (correct)
  • Through electrophoresis
  • Through mass spectrometry

Which protein is the second most predominant in cerebrospinal fluid?

<p>Albumin (A)</p> Signup and view all the answers

What technique is used to differentiate proteins based on electrical charge?

<p>Ion-exchange chromatography (B)</p> Signup and view all the answers

Which protein is primarily produced in the liver and is considered an acute phase protein?

<p>Haptoglobin (A)</p> Signup and view all the answers

In which conditions would you expect to find decreased levels of haptoglobin?

<p>Liver disease (B)</p> Signup and view all the answers

Which protein accounts for the majority of α-2-globulin and is found principally in the intravascular spaces?

<p>Haptoglobin (B)</p> Signup and view all the answers

What protein is a light chain component of the major human leukocyte antigen (HLA) and found on the surface of most nucleated cells, with high concentrations on lymphocytes?

<p>Beta2-Microglobulin (B)</p> Signup and view all the answers

Which marker can be used for acute myocardial infarction but is not specific for this condition?

<p>Myoglobin (B)</p> Signup and view all the answers

In which muscle-related disorders can myoglobin levels be elevated besides acute myocardial infarction?

<p>Cardiac and skeletal muscle disorders (D)</p> Signup and view all the answers

Which specimen is most commonly preferred for protein testing?

<p>Serum (B)</p> Signup and view all the answers

In which body fluid can protein levels help differentiate between transudate and exudate?

<p>CSF (C)</p> Signup and view all the answers

Which factor causes false decrease in protein levels in the biuret method?

<p>High ammonia level (C)</p> Signup and view all the answers

Which method is preferred for rapidly estimating protein at high concentrations?

<p>Refractometry (C)</p> Signup and view all the answers

What causes gamma globulins to migrate towards the cathodes during electrophoresis despite having a slightly negative charge?

<p>Electroendosmosis (C)</p> Signup and view all the answers

Which condition is associated with an increase in the alpha-2 region and a decrease in albumin?

<p>Nephrotic syndrome (A)</p> Signup and view all the answers

What is the main purpose of the Folin-Ciocalteu Method?

<p>To detect proteins in low concentrations (B)</p> Signup and view all the answers

What is the key factor that causes false increased reference range readings in the biuret method?

<p>High bilirubin (C)</p> Signup and view all the answers

What is used to complex cupric ions and prevent precipitation in the Biuret method?

<p>Rochelle salt (B)</p> Signup and view all the answers

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