Protein Function Prediction Methods
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Questions and Answers

What is the main challenge in postgenomic era?

  • Sequencing the entire genome
  • Identifying new protein functions using genomic sequence data
  • Functionally characterizing newly discovered proteins (correct)
  • Determining the structure of proteins
  • Why do early approaches to protein function prediction fail?

  • They rely too heavily on homology relationships (correct)
  • They do not use machine learning techniques
  • They are too complex and computationally expensive
  • They are not yet fully developed
  • What percentage of proteins in the NCBI database have no assigned function?

  • 20%
  • 30%
  • 50%
  • 40% (correct)
  • What is the purpose of protein function prediction?

    <p>To assign biological or biochemical roles to proteins</p> Signup and view all the answers

    Why are machine learning approaches currently applied to protein function prediction problems?

    <p>Because they are more accurate than other approaches</p> Signup and view all the answers

    What is a limitation of early approaches to protein function prediction?

    <p>They rely on homology relationships</p> Signup and view all the answers

    What is the result of the exponential increase in the number of newly identified proteins?

    <p>An increase in the number of proteins with unknown function</p> Signup and view all the answers

    What is needed to address the gap in functional characterization of newly discovered proteins?

    <p>More accurate approaches using expressive data representation and sophisticated computational techniques</p> Signup and view all the answers

    What is the goal of protein function prediction?

    <p>To assign biological or biochemical roles to proteins</p> Signup and view all the answers

    Why are computational methods necessary for protein function prediction?

    <p>Because they can handle large amounts of genomic sequence data</p> Signup and view all the answers

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