8 Questions
What is the percentage of O2 saturation in hemoglobin at the O2 pressure in the lung alveoli?
100%
In active muscle, at what percentage is hemoglobin saturated with O2?
32%
How much of their bound O2 molecules do hemoglobin molecules give up during each passage through the circulation?
66%
What does positive cooperativity improve in terms of O2 delivery?
O2 delivery efficiency
What structural modification occurs between the α and ß subunits of hemoglobin tetramer during cooperative binding?
Increase in contacts
What stabilizes the structure of deoxyhemoglobin during O2 binding?
Salt-bridge contacts between α and β chains
What happens to the heme group's iron during O2 binding?
It pulls directly into the heme plane
What changes shape within the subunit during O2 binding?
'T' helix
Test your knowledge on protein folding and quaternary structure featuring the cytochrome c fold and multisubunit proteins. Explore concepts such as subunit arrangement and oligomers within proteins.
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