Protein Folding 101

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HighSpiritedCanyon
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5 Questions

Which factor is the main thermodynamic force driving protein folding?

Hydrophobic effect

What is the enthalpic contribution to protein folding provided by?

Van der Waals interactions

What is the entropic contribution to protein folding?

Minimization of solvent-accessible surface area

What is required for the burial of hydrophobic R groups away from water?

At least 2 interacting secondary elements

What guides correct folding rather than driving it thermodynamically?

Hydrogen bonding

Test your knowledge on the fundamental principles of protein folding with this quiz! Learn about the factors that contribute to the folding of water-soluble proteins and how they achieve their native structures. Explore concepts such as minimizing solvent-accessible surface area, maximizing intraprotein hydrogen bonds, and close packing for optimal van der Waals interactions.

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