Podcast
Questions and Answers
Which factor is the main thermodynamic force driving protein folding?
Which factor is the main thermodynamic force driving protein folding?
- Minimization of solvent-accessible surface area
- Hydrophobic effect (correct)
- Maximization of intraprotein hydrogen bonds
- Maximization of van der Waals interactions
What is the enthalpic contribution to protein folding provided by?
What is the enthalpic contribution to protein folding provided by?
- Hydrophobic effect
- Hydrogen bonding
- Van der Waals interactions (correct)
- Ionic interactions
What is the entropic contribution to protein folding?
What is the entropic contribution to protein folding?
- Maximization of van der Waals interactions
- Maximization of intraprotein hydrogen bonds
- Hydrophobic effect
- Minimization of solvent-accessible surface area (correct)
What is required for the burial of hydrophobic R groups away from water?
What is required for the burial of hydrophobic R groups away from water?
What guides correct folding rather than driving it thermodynamically?
What guides correct folding rather than driving it thermodynamically?