Protein Folding and Stability Quiz
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Questions and Answers

Which of the following determines the folding of a single strand of protein into a 3D structure?

  • Hydrophobic effect
  • Secondary structures
  • Chaperones
  • Formation of hydrogen bonds (correct)
  • What is the role of chaperones in protein folding?

  • They reduce strain
  • They stabilize the protein
  • They induce compact folding
  • They assist with folding (correct)
  • What are the two phenomena that assist in stabilizing the protein during folding?

  • Chaperones and hydrophobic effect
  • Secondary structures and polar groups
  • Hydrogen bonding and hydrophobic collapse
  • Formation of hydrogen bonds and reduction of surface area (correct)
  • What induces compact folding of proteins by internalizing hydrophobic amino acids?

    <p>Hydrophobic effect</p> Signup and view all the answers

    Which structures fold first during protein folding?

    <p>Secondary structures</p> Signup and view all the answers

    Which of the following is true about protein folding in dilute solution?

    <p>Proteins can fold without the assistance of chaperones.</p> Signup and view all the answers

    What is the role of hydrogen bonding in protein folding?

    <p>Hydrogen bonding reduces strain in the protein backbone.</p> Signup and view all the answers

    What is the hydrophobic effect in protein folding?

    <p>It is the internalization of hydrophobic amino acids from the aqueous solution.</p> Signup and view all the answers

    What is the most stable conformation of a protein?

    <p>The tertiary structure.</p> Signup and view all the answers

    Can proteins fold reversibly?

    <p>Yes, proteins can fold reversibly.</p> Signup and view all the answers

    What are some trends in protein folding?

    <p>Secondary structures fold first. Nonpolar residues aggregate or form a hydrophobic collapse.</p> Signup and view all the answers

    How are proteins able to fold without chaperones?

    <p>In dilute solution, proteins can be folded without chaperones.</p> Signup and view all the answers

    What are the two phenomena that assist in stabilizing the protein during folding?

    <p>Formation of lots of hydrogen bonds and reduction of surface area accessible to the aqueous solvent.</p> Signup and view all the answers

    What role does the hydrophobic effect play in protein folding?

    <p>The hydrophobic effect induces compact folding of proteins by internalizing hydrophobic amino acids from the aqueous solution.</p> Signup and view all the answers

    Are proteins able to fold reversibly?

    <p>Yes, proteins can fold reversibly.</p> Signup and view all the answers

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