Podcast
Questions and Answers
What is the final product of the conversion of diacylglycerol to phosphatidylcholine?
What is the final product of the conversion of diacylglycerol to phosphatidylcholine?
- Phosphatidic acid
- Phosphocholine (correct)
- Phospholipid flippase
- Phosphatase
Where are phospholipids synthesized in relation to the ER membrane?
Where are phospholipids synthesized in relation to the ER membrane?
- On the luminal side of the ER membrane
- In the Golgi apparatus
- On both sides of the ER membrane simultaneously
- On the cytosolic side of the ER membrane (correct)
What facilitates the transfer of phospholipids to the lumenal half of the ER bilayer?
What facilitates the transfer of phospholipids to the lumenal half of the ER bilayer?
- Flippases (correct)
- Mitochondria
- Ribosomes
- Golgi apparatus
Where are large amounts of smooth ER typically found?
Where are large amounts of smooth ER typically found?
What is the primary function of smooth ER in the liver?
What is the primary function of smooth ER in the liver?
Which process occurs at the smooth ER?
Which process occurs at the smooth ER?
What is the role of the signal recognition particle (SRP) in cotranslational targeting of secretory proteins to the ER?
What is the role of the signal recognition particle (SRP) in cotranslational targeting of secretory proteins to the ER?
What happens after the signal recognition particle (SRP) escorts the complex to the ER membrane?
What happens after the signal recognition particle (SRP) escorts the complex to the ER membrane?
Which step involves the insertion of the signal sequence into the translocon during cotranslational targeting of secretory proteins to the ER?
Which step involves the insertion of the signal sequence into the translocon during cotranslational targeting of secretory proteins to the ER?
What drives the translocation of the growing polypeptide chain across the membrane during cotranslational targeting to the ER?
What drives the translocation of the growing polypeptide chain across the membrane during cotranslational targeting to the ER?
Which enzyme is responsible for cleaving the signal sequence during cotranslational targeting of secretory proteins to the ER?
Which enzyme is responsible for cleaving the signal sequence during cotranslational targeting of secretory proteins to the ER?
Where are glycolipids and sphingomyelin synthesized?
Where are glycolipids and sphingomyelin synthesized?
How are proteins transported from the Golgi apparatus to their final destinations?
How are proteins transported from the Golgi apparatus to their final destinations?
What is one function of the Golgi apparatus besides processing glycoproteins?
What is one function of the Golgi apparatus besides processing glycoproteins?
Where are ceramide, cholesterol, and glycerol phospholipids synthesized?
Where are ceramide, cholesterol, and glycerol phospholipids synthesized?
What is the process known as when proteins are targeted to late endosomes that develop into lysosomes?
What is the process known as when proteins are targeted to late endosomes that develop into lysosomes?
In polarized epithelial cells, how are plasma membranes divided?
In polarized epithelial cells, how are plasma membranes divided?
What is the role of Arf/GTP in vesicle formation?
What is the role of Arf/GTP in vesicle formation?
Where are lysosomes formed?
Where are lysosomes formed?
What happens when Dynamin constricts the neck of a vesicle?
What happens when Dynamin constricts the neck of a vesicle?
What is one major function of lysosomes?
What is one major function of lysosomes?
Where are active drugs processed in the cell?
Where are active drugs processed in the cell?
What leads to the formation of lysosomes?
What leads to the formation of lysosomes?
What is the final destination for transmembrane proteins after they are inserted into the ER membrane?
What is the final destination for transmembrane proteins after they are inserted into the ER membrane?
Where are the portions of polypeptide chains that are translocated into the ER exposed following transport to the plasma membrane?
Where are the portions of polypeptide chains that are translocated into the ER exposed following transport to the plasma membrane?
How are membrane proteins with internal transmembrane sequences inserted in the ER membrane?
How are membrane proteins with internal transmembrane sequences inserted in the ER membrane?
Which region of a protein directs the insertion of a polypeptide chain into the ER membrane?
Which region of a protein directs the insertion of a polypeptide chain into the ER membrane?
What happens to a polypeptide chain after its transmembrane sequence exits the translocon during insertion into the ER membrane?
What happens to a polypeptide chain after its transmembrane sequence exits the translocon during insertion into the ER membrane?
What is the topological equivalence between the lumens of the ER and Golgi apparatus?
What is the topological equivalence between the lumens of the ER and Golgi apparatus?
