Podcast
Questions and Answers
What effect does adrenaline have on the heart when administered in high doses or too rapidly?
What effect does adrenaline have on the heart when administered in high doses or too rapidly?
Which drug is known as a cardiac β-receptor antagonist?
Which drug is known as a cardiac β-receptor antagonist?
What is the primary action of atropine in the context of this experiment?
What is the primary action of atropine in the context of this experiment?
What occurs to the heart rhythm after the administration of propranolol?
What occurs to the heart rhythm after the administration of propranolol?
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How does the heart rate change after administering atropine?
How does the heart rate change after administering atropine?
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What is the recommended method for administering adrenaline in this context?
What is the recommended method for administering adrenaline in this context?
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What is the effect observed after the second administration of adrenaline?
What is the effect observed after the second administration of adrenaline?
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Which statement accurately describes the sequence of drug administration?
Which statement accurately describes the sequence of drug administration?
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Study Notes
Effect of Propranolol on Adrenaline-Induced Arrhythmia
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Adrenaline: A beta-agonist; activates beta receptors in the heart, increasing heart rate and excitation. High doses or rapid injection can trigger cardiac arrhythmias.
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Propranolol: A beta receptor antagonist; blocks beta receptor activation, thus potentially decreasing heart rate and arrhythmias.
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Atropine: An M receptor antagonist that accelerates the heart by blocking parasympathetic inhibition.
Drug Administration Protocol
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Adrenaline (1st dose): Administer 0.3 ml/kg of 0.02% adrenaline rapidly. Record ECG 5 minutes later.
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Propranolol: Administer 0.5 ml/kg of 0.2% propranolol slowly if the ECG appears normal after adrenaline. Record ECG 5 minutes later.
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Atropine: Administer 1.6 ml/kg of 0.1% atropine. Record ECG 1-2 minutes later.
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Repeat steps 1, 2, and 5 as outlined above to complete the study.
Cautions and Considerations
- Adrenaline should be administered rapidly.
- Propranolol should be administered slowly.
- Explore the differing impacts of adrenaline, propranolol, and atropine on heart rate and blood pressure.
- Determine whether repeated adrenaline administration has a varying effect.
Results Summary
| 1st Adrenaline | Propranolol | 2nd Adrenaline | Atropine | 2nd Propranolol | 3rd Adrenaline | |
|---|---|---|---|---|---|---|
| Heart rate | Slow-fast | Slow | Slow | Faster | No change | No change |
| Rhythm | Obvious arrhythmia | Normal | Rare anomalies | Normal | Normal | No change |
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Description
Explore the effects of propranolol on adrenaline-induced arrhythmias through this quiz. Test your understanding of drug administration protocols, including dosage and timing for adrenaline, propranolol, and atropine. This quiz is essential for those studying pharmacology and cardiology.
