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Questions and Answers
Which neurotransmitter does propofol enhance the effects of?
Which neurotransmitter does propofol enhance the effects of?
- Glutamate
- Dopamine
- Serotonin
- GABA (correct)
What is the primary mechanism of action of fentanyl?
What is the primary mechanism of action of fentanyl?
- Blocking serotonin receptors
- Inhibiting glutamate production
- Activating opioid receptors (correct)
- Enhancing dopamine release
Which opioid receptor does fentanyl primarily bind to?
Which opioid receptor does fentanyl primarily bind to?
- Sigma opioid receptor
- Mu opioid receptor (correct)
- Delta opioid receptor
- Kappa opioid receptor
What is the recommended maintenance rate for propofol?
What is the recommended maintenance rate for propofol?
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What is the usual dosing range for morphine?
What is the usual dosing range for morphine?
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Study Notes
Propofol
- Enhances the effects of GABA (Gamma-Aminobutyric Acid), which is the primary inhibitory neurotransmitter in the brain.
- Commonly used for sedation and anesthesia due to its rapid action and quick recovery times.
Fentanyl
- Primarily acts as a potent agonist at the mu-opioid receptor, providing significant analgesic effects.
- Its rapid onset and short duration of action make it a preferred choice in acute pain management and anesthesia.
Morphine
- Usual dosing range for morphine is typically between 2 mg to 10 mg for intravenous administration, depending on the indication, patient's condition, and previous opioid exposure.
- Acts primarily on mu-opioid receptors to alleviate moderate to severe pain.
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Description
Test your knowledge on the mechanism of action of propofol and its role in sedation and anesthesia. Learn about the enhancement of GABA neurotransmitter effects and reduction of excitatory neurotransmitters.
