Propofol
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Questions and Answers

Which neurotransmitter does propofol enhance the effects of?

  • Glutamate
  • Dopamine
  • Serotonin
  • GABA (correct)
  • What is the primary mechanism of action of fentanyl?

  • Blocking serotonin receptors
  • Inhibiting glutamate production
  • Activating opioid receptors (correct)
  • Enhancing dopamine release
  • Which opioid receptor does fentanyl primarily bind to?

  • Sigma opioid receptor
  • Mu opioid receptor (correct)
  • Delta opioid receptor
  • Kappa opioid receptor
  • What is the recommended maintenance rate for propofol?

    <p>5 to 50 mcg/kg/min</p> Signup and view all the answers

    What is the usual dosing range for morphine?

    <p>2-4 mg</p> Signup and view all the answers

    Study Notes

    Propofol

    • Enhances the effects of GABA (Gamma-Aminobutyric Acid), which is the primary inhibitory neurotransmitter in the brain.
    • Commonly used for sedation and anesthesia due to its rapid action and quick recovery times.

    Fentanyl

    • Primarily acts as a potent agonist at the mu-opioid receptor, providing significant analgesic effects.
    • Its rapid onset and short duration of action make it a preferred choice in acute pain management and anesthesia.

    Morphine

    • Usual dosing range for morphine is typically between 2 mg to 10 mg for intravenous administration, depending on the indication, patient's condition, and previous opioid exposure.
    • Acts primarily on mu-opioid receptors to alleviate moderate to severe pain.

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    Description

    Test your knowledge on the mechanism of action of propofol and its role in sedation and anesthesia. Learn about the enhancement of GABA neurotransmitter effects and reduction of excitatory neurotransmitters.

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