5 Questions
Which substance is used as the oil phase in the formulation of propofol?
Soybean oil
What is the equivalent dose of propofol to induce unconsciousness compared to thiopental?
1.5 to 2.5 mg/kg IV
How long does it take for propofol to produce unconsciousness when administered as a rapid IV injection?
About 30 seconds
What is one of the most important advantages of propofol?
Rapid return of consciousness with minimal residual in the Central Nervous System (CNS)
Which drug is NOT used for rapid IV induction of anesthesia?
Isopropylphenol
Study Notes
Propofol Formulation
- Intralipid 10% (soybean oil and egg phospholipid) is used as the oil phase in the formulation of propofol.
Comparative Anesthesia
- Propofol is approximately 2-3 times more potent than thiopental in inducing unconsciousness.
Pharmacokinetics of Propofol
- Rapid IV injection of propofol produces unconsciousness in approximately 15-30 seconds.
Advantages of Propofol
- One of the most important advantages of propofol is its rapid recovery profile.
Anesthesia Options
- Ketamine is not typically used for rapid IV induction of anesthesia.
Test your knowledge on propofol administration and its equivalency to other IV drugs. Learn about the composition and dosage of propofol, and understand its effects when administered rapidly.
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