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Questions and Answers
Which substance is used as the oil phase in the formulation of propofol?
Which substance is used as the oil phase in the formulation of propofol?
- Isopropylphenol
- Purified egg phosphatide
- Glycerol
- Soybean oil (correct)
What is the equivalent dose of propofol to induce unconsciousness compared to thiopental?
What is the equivalent dose of propofol to induce unconsciousness compared to thiopental?
- 1.5 mg/kg IV
- 1.5 to 2.5 mg/kg IV (correct)
- 4 to 5 mg/kg IV
- 2.6 mg/kg IV
How long does it take for propofol to produce unconsciousness when administered as a rapid IV injection?
How long does it take for propofol to produce unconsciousness when administered as a rapid IV injection?
- About 1 minute
- About 5 minutes
- About 30 seconds (correct)
- Less than 15 seconds
What is one of the most important advantages of propofol?
What is one of the most important advantages of propofol?
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Which drug is NOT used for rapid IV induction of anesthesia?
Which drug is NOT used for rapid IV induction of anesthesia?
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Study Notes
Propofol Formulation
- Intralipid 10% (soybean oil and egg phospholipid) is used as the oil phase in the formulation of propofol.
Comparative Anesthesia
- Propofol is approximately 2-3 times more potent than thiopental in inducing unconsciousness.
Pharmacokinetics of Propofol
- Rapid IV injection of propofol produces unconsciousness in approximately 15-30 seconds.
Advantages of Propofol
- One of the most important advantages of propofol is its rapid recovery profile.
Anesthesia Options
- Ketamine is not typically used for rapid IV induction of anesthesia.
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Description
Test your knowledge on propofol administration and its equivalency to other IV drugs. Learn about the composition and dosage of propofol, and understand its effects when administered rapidly.
