Progressive Nature of Type 2 Diabetes

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30 Questions

What is the abbreviation 'IFG' used for in the text?

Impaired Fasting Glucose

What is an outcome of intensive therapy for maintaining normoglycemia?

Reduction in long-term complications

What is a primary goal of therapy for Type 2 Diabetes mentioned in the text?

Ensure glycemic control

What does the text mention as an issue in therapy for Type 2 Diabetes?

Inability to control sugar & metabolic abnormality

What is the rate of progressive loss of beta cell function despite treatment mentioned in the text?

4-5% yearly

Which type of glucose level is specifically mentioned as being 300 mg/dL in the text?

Postmeal Glucose

What are some of the factors that can impact the effectiveness of interventions for diabetes management?

Metabolic factors like obesity

Which of the following is NOT considered a factor in intervention effectiveness for diabetes management?

Eye color of the patient

What is an important consideration when evaluating the effectiveness of drugs for type 2 diabetes?

Ease of use of the drug

What aspect of a drug's action can impact its effectiveness in lowering glucose levels?

Rapidity of onset

In the context of drugs for type 2 diabetes, what is an important consideration related to beneficial effects and side effects?

The cost of therapy

Which factor is NOT typically considered when assessing the effectiveness of interventions for diabetes management?

Patient's favorite television show

What is the role of sulfonylureas in glucose homeostasis?

Stimulating insulin release

Which organ shows increased gluconeogenesis due to impaired insulin secretion?

Liver

What is a common unwanted effect associated with sulfonylureas?

Weight gain due to increased appetite

In which type of diabetes mellitus are sulfonylureas contraindicated?

Type 1 DM

What is a major factor contributing to secondary failure of sulfonylureas?

Severe liver impairment

What is a common symptom associated with hypoglycemia caused by sulfonylureas?

Nausea and upset stomach

Which type of drug blocks the KATP channel and acts as an insulin sensitizer in the liver?

TZD thiazolidinedione

What is the primary unwanted effect associated with pharmaceutical insulin preparations?

Hypoglycemia

Which drug works by inhibiting the absorption of dietary glucose in the intestine?

SGLT2 inhibitors

Which type of insulin has a peak action approximately 2-4 hours after subcutaneous injection?

Short-acting insulin

What is the main function of sulfonylureas in the treatment of Type 2 Diabetes Mellitus?

Stimulating insulin release from pancreatic beta cells

Which class of anti-diabetic drugs acts on the brain, nervous system, muscle, and fat cells to increase insulin sensitivity?

Thiazolidinediones

What is the recommended duration of aerobic exercise per session for diabetic patients?

20-30 minutes

Which drug category includes metformin for treating Diabetes Mellitus?

Insulin sensitizers

Which drug type helps in reducing glucose production by the liver?

Biguanides

Which drug class includes GLP-1 analogs like exenatide?

Incretin enhancers

Which drug category includes drugs like pioglitazone?

Insulin sensitizers

Which drug type is represented by acarbose for managing diabetes?

Incretin modulators

Explore the progressive nature of Type 2 Diabetes through a study on obesity, uncontrolled hyperglycemia, glucose levels, insulin resistance, and beta-cell function over the course of years. Understand how clinical symptoms develop and the relative functions of different parameters.

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