18 Questions
Which of the following is a characteristic of qualitative disorders of platelets?
Abnormal platelet function
In Bernard Soulier Syndrome (BSS), which platelet surface protein complex is missing or dysfunctional?
GPIb/IX/V
What is the primary consequence of the absence or dysfunction of the GPIb/IX/V complex in Bernard Soulier Syndrome?
Defective platelet adhesion
Which of the following is a characteristic of thrombocytopenia?
Decreased platelet count
Which of the following conditions is associated with an increase in platelet count?
Thrombocytosis
Which of the following is a myeloproliferative or lymphoproliferative disorder that can lead to an increased platelet count?
All of the above
What does the suffix 'itis' attached after an organ mean according to Robins from general pathology?
Inflammation
Which therapeutic drug is mentioned in the text?
Vincristine
What condition makes a person unable to become pregnant while taking Vitamin A?
All-Trans-Retenoic Acid consumption
Which of the following are examples of cytokines as mentioned in the text?
Interleukins, Tumor Necrosis Factor, Erythropoietin
Which clinical findings can help distinguish between clonal and secondary/reactive thrombocytosis?
Essential Thrombocythemia and Myeloproliferative Disorders
Which of the following are among the myeloproliferative disorders mentioned in the text?
Polycythemia Vera, CML, Myelofibrosis
What is the characteristic of platelets in Quebec Platelet Syndrome?
Normal to reduced platelet count with proteolytic degradation of -granule proteins
Which component of the thromboxane pathway is not mentioned in the text?
Lipoxygenase
What is the term used to describe hereditary absence or abnormalities of the components of the thromboxane pathway?
Aspirin-like defects
What is the inheritance pattern of Quebec Platelet Syndrome?
Autosomal dominant
Which of the following is a component of the dense granules in platelets?
Serotonin
Which of the following is a characteristic of Bernard Soulier Syndrome (BSS)?
Absence or abnormality of the glycoprotein Ib-IX-V complex
Learn about the prognosis of Chronic Myeloid Leukemia (CML) in the absence of the Philadelphia chromosome. This quiz covers the impact of the chromosome anomaly on the disease outlook.
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