Chronic Myeloid Leukemia (CML) Overview

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5 Questions

Match the following symptoms with the corresponding description:

Fatigue = Early symptom of CML Night sweats = Early symptom of CML Abdominal pain = Later symptom of CML due to splenomegaly Bone pain = Later symptom of CML

Match the following laboratory tests with their corresponding descriptions:

Philadelphia chromosome translocation = Demonstration of Ph-chromosome Bone marrow biopsy = Shows small megakaryocytes with hypolobulated nuclei Lab tests = Demonstration of the Ph-chromosome is the No.1 specific test Biopsy = Shows dwarf megakaryocytes

Match the following treatment options with their corresponding descriptions:

Imatinib = BCR-ABL tyrosine kinase inhibitor (TKI) BM-transplantation = Attempted early for a cure Alpha-interferon = Helps eliminate the Ph-chromosome TKI = Given in the chronic phase of CML

Match the following CML characteristics with their corresponding descriptions:

Etiology = Unknown Philadelphia chromosome translocation = Leads to tyrosine kinase enzyme activity Chronic myeloproliferative neoplasm = Characterized by the massive overproduction of myeloid cells CML = A type of leukemia

Match the following differential diagnoses with their corresponding descriptions:

Leukemoid reactions = A differential diagnosis of CML CML = A type of chronic myeloproliferative neoplasm BM-transplantation = A treatment option for CML Alpha-interferon = A treatment option for CML

Learn the essential facts and diagnosis criteria for Chronic Myeloid Leukemia (CML), a myeloproliferative neoplasm. Understand the disease's etiology, symptoms like fatigue and abdominal pain, and diagnostic tests like demonstrating the Ph-chromosome.

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