Podcast
Questions and Answers
Which drug is commonly used for symptomatic relief of dyspepsia but is rarely used as the primary therapeutic agent for peptic ulcers?
Which drug is commonly used for symptomatic relief of dyspepsia but is rarely used as the primary therapeutic agent for peptic ulcers?
- Histamine inhibitors
- Antacids (correct)
- NSAIDs
- H. pylori eradication drugs
Which combination of antacids is commonly used to avoid constipation and phosphate depletion?
Which combination of antacids is commonly used to avoid constipation and phosphate depletion?
- Aluminum hydroxide and magnesium hydroxide (correct)
- Aluminum hydroxide and calcium carbonate
- Calcium carbonate and sodium bicarbonate
- Magnesium hydroxide and sodium bicarbonate
Which antacid should not be used in patients with chronic renal failure due to the risk of hypermagnesemia?
Which antacid should not be used in patients with chronic renal failure due to the risk of hypermagnesemia?
- Sodium bicarbonate
- Aluminum hydroxide
- Calcium carbonate
- Magnesium hydroxide (correct)
What potential problem can arise from long-term use of calcium carbonate as an antacid?
What potential problem can arise from long-term use of calcium carbonate as an antacid?
Which drug may induce systemic alkalosis when used as an antacid?
Which drug may induce systemic alkalosis when used as an antacid?
Which of the following is a potential side effect of long-term use of PPIs?
Which of the following is a potential side effect of long-term use of PPIs?
Which of the following is a potential drug interaction involving PPIs?
Which of the following is a potential drug interaction involving PPIs?
Which of the following is a recommendation for patients taking clopidogrel with aspirin and other GI risk factors for bleeding?
Which of the following is a recommendation for patients taking clopidogrel with aspirin and other GI risk factors for bleeding?
Which of the following is a potential side effect of long-term PPI use?
Which of the following is a potential side effect of long-term PPI use?
Which of the following is a potential risk factor for long-term side effects of PPIs?
Which of the following is a potential risk factor for long-term side effects of PPIs?
Which H2 receptor antagonist is associated with weak antiandrogenic side effects such as reversible gynecomastia and impotence?
Which H2 receptor antagonist is associated with weak antiandrogenic side effects such as reversible gynecomastia and impotence?
Which H2 receptor antagonist does not bind to hepatic cytochrome P450?
Which H2 receptor antagonist does not bind to hepatic cytochrome P450?
Which H2 receptor antagonist was taken off the market due to contamination with a known carcinogen?
Which H2 receptor antagonist was taken off the market due to contamination with a known carcinogen?
Which proton pump inhibitor has a dual delayed-release system aimed at improving treatment of gastroesophageal reflux disease (GERD)?
Which proton pump inhibitor has a dual delayed-release system aimed at improving treatment of gastroesophageal reflux disease (GERD)?
Which proton pump inhibitor is available in an orally disintegrating tablet that can be taken with or without water?
Which proton pump inhibitor is available in an orally disintegrating tablet that can be taken with or without water?
Which of the following is NOT a potential side effect of long-term PPI use?
Which of the following is NOT a potential side effect of long-term PPI use?
What is the mechanism for PPI-induced collagenous colitis?
What is the mechanism for PPI-induced collagenous colitis?
Which of the following drugs may interact significantly with PPIs?
Which of the following drugs may interact significantly with PPIs?
What is the main reason why PPIs are maximized if administered before a meal?
What is the main reason why PPIs are maximized if administered before a meal?
How long does it take for gastric acid secretion to return to normal levels after discontinuation of PPIs?
How long does it take for gastric acid secretion to return to normal levels after discontinuation of PPIs?
Which class of agents inhibits gastric acid secretion via potassium competitive binding of the H+,K+-ATPase?
Which class of agents inhibits gastric acid secretion via potassium competitive binding of the H+,K+-ATPase?
Which agent has been awarded Fast Track status by the FDA for the treatment of H. pylori in combination with both amoxicillin and clarithromycin and with amoxicillin alone?
Which agent has been awarded Fast Track status by the FDA for the treatment of H. pylori in combination with both amoxicillin and clarithromycin and with amoxicillin alone?
Which compound becomes a viscous paste within the stomach and duodenum, binding primarily to sites of active ulceration?
Which compound becomes a viscous paste within the stomach and duodenum, binding primarily to sites of active ulceration?
Which bismuth-containing compound is commonly used as one of the agents in an anti-H. pylori regimen?
Which bismuth-containing compound is commonly used as one of the agents in an anti-H. pylori regimen?
What is the main toxicity associated with prostaglandin analogues used for the treatment of PUD?
What is the main toxicity associated with prostaglandin analogues used for the treatment of PUD?
Which of the following is NOT a concern raised about the widespread use of antibiotics for H. pylori therapy?
Which of the following is NOT a concern raised about the widespread use of antibiotics for H. pylori therapy?
Which of the following is the most effective treatment duration for H. pylori therapy?
Which of the following is the most effective treatment duration for H. pylori therapy?
Which of the following is NOT one of the agents frequently used in H. pylori therapy?
Which of the following is NOT one of the agents frequently used in H. pylori therapy?
What factors should be considered when choosing a particular H. pylori therapy regimen?
What factors should be considered when choosing a particular H. pylori therapy regimen?
Why is dual therapy not recommended for H. pylori eradication?
Why is dual therapy not recommended for H. pylori eradication?
