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Questions and Answers
Where do post-translational modifications of peptide chain occur?
What is the primary characteristic of prions?
What is the result of the presence of abnormal prion particles or beta-plated prion particles?
What do prions convert normal proteins into?
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What are the pathological prion proteins resistant to?
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Study Notes
Post-Translational Modifications
- Post-translational modifications of peptide chain occur in the cytoplasm.
Prion Characteristics
- Primary characteristic of prions: infectious proteins that can cause normal proteins to fold abnormally.
Prion Consequences
- Presence of abnormal prion particles or beta-plated prion particles leads to neurodegenerative diseases.
Prion Conversion
- Prions convert normal proteins into abnormal, infectious prion proteins.
Prion Protein Resistance
- Pathological prion proteins are resistant to proteolytic degradation and heat denaturation.
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Description
Test your knowledge about prions, their unique characteristics, and their role in causing prion-related diseases. Learn about how prions can corrupt naturally produced proteins, leading to the accumulation of pathological beta-plated particles and the development of amyloidosis.
