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Questions and Answers
Where do post-translational modifications of peptide chain occur?
Where do post-translational modifications of peptide chain occur?
- Nucleus
- Endoplasmic reticulum and golgi operators (correct)
- Mitochondria
- Cytoplasm
What is the primary characteristic of prions?
What is the primary characteristic of prions?
- They contain DNA and RNA
- They are digested by the body
- They replicate through cellular division
- They corrupt naturally produced proteins (correct)
What is the result of the presence of abnormal prion particles or beta-plated prion particles?
What is the result of the presence of abnormal prion particles or beta-plated prion particles?
- Misfolding of newly formed proteins (correct)
- Enhanced digestion of prions
- Conversion of prions into DNA
- Reduced protein accumulation
What do prions convert normal proteins into?
What do prions convert normal proteins into?
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What are the pathological prion proteins resistant to?
What are the pathological prion proteins resistant to?
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Study Notes
Post-Translational Modifications
- Post-translational modifications of peptide chain occur in the cytoplasm.
Prion Characteristics
- Primary characteristic of prions: infectious proteins that can cause normal proteins to fold abnormally.
Prion Consequences
- Presence of abnormal prion particles or beta-plated prion particles leads to neurodegenerative diseases.
Prion Conversion
- Prions convert normal proteins into abnormal, infectious prion proteins.
Prion Protein Resistance
- Pathological prion proteins are resistant to proteolytic degradation and heat denaturation.
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