Prion Diseases Manifestations Quiz

The passage mentions Creutzfeldt-Jacob, kuru, iatrogenic, and genetic diseases such as fatal familial insomnia and genetic Creutzfeldt-Jacob and Gerstmann-Strussler Scheinker syndrome.

It can be challenging to diagnose PrD due to the lack of specific tests.

PrD are manifested by the misfolding of prion proteins within brain cells, resulting in ballooned neurons. They can lead to myoclonus, parkinsonian features, and rapidly progressive dementia.

<p>myoclonus, parkinsonian features, rapidly progressive dementia</p> Signup and view all the answers

<p>Diagnostic criteria have been developed to facilitate clinical diagnosis for clinicians.</p> Signup and view all the answers

<p>accumulation of misfolding prion proteins</p> Signup and view all the answers

<p>fatal familial insomnia, genetic Creutzfeldt-Jacob</p> Signup and view all the answers

<p>lack of specific tests</p> Signup and view all the answers

<p>misfolding prion proteins</p> Signup and view all the answers

<p>Misfolded prion proteins accumulate within brain cells, resulting in ballooned neurons, which leads to the manifestation of PrD.</p> Signup and view all the answers

<p>The term 'transmissible' implies that PrD can be transmitted or passed on from one individual to another.</p> Signup and view all the answers

<p>PrD can be challenging to diagnose due to the lack of specific tests, which necessitates the development of diagnostic criteria to facilitate clinical diagnosis.</p> Signup and view all the answers

<p>The term 'spongiform' refers to the sponge-like appearance of the brain tissue in PrD, likely due to the ballooned neurons.</p> Signup and view all the answers

<p>The rapidly progressive nature of PrD, as mentioned in the passage, implies that the disease progresses quickly, potentially leading to severe consequences and the need for prompt diagnosis and treatment.</p> Signup and view all the answers