20 Questions
Which type of cells are responsible for supporting the function of neurons?
Astrocytes
How many connections does each neuron typically have?
1,000-10,000
What is the role of glia cells in the nervous system?
Supporting function
What are the specialized sites where neurons communicate with other cells via neurotransmitters called?
Synapses
What are the four steps involved in neurotransmission?
Synthesis, storage, release, termination
Where is neurotransmitter synthesis usually carried out?
Cytosol
What is the classification of neurotransmitters that are small molecules?
Classical NTs
What are neuropeptides?
Short peptides that are neuroactive
What is the role of oligodendrocytes and Schwann cells?
Supporting function
Which of the following is NOT one of the classical (small molecule) neurotransmitters?
Arachidonic acid
What is the role of the myelin sheath in the transmission of electrical signals?
All of the above
What is the function of Ca2+ in neurotransmitter release?
It converts the electrical signal into a chemical signal
Which proteins control the fusion of the synaptic vesicle membrane with the presynaptic membrane?
SNARE proteins
Which of the following diseases is NOT associated with abnormalities in neurotransmission at neuromuscular synapses?
Botulinum toxin
What is the role of the heavy chain of botulinum toxin in the neuromuscular junction (NMJ)?
It facilitates the entry of the toxin into neurons
What are the medical uses of botulinum toxin?
All of the above
What are the two main kinds of neurotransmitter receptors?
Ionotropic and metabotropic
How do ionotropic receptors differ from metabotropic receptors?
All of the above
What are the main mechanisms for the termination of the effect of a neurotransmitter?
Enzymatic degradation, uptake into neurons, and diffusion away from synaptic cleft
Test your knowledge on the principles of CNS neurotransmission with this quiz! Explore topics such as the nervous system, neurons, glia, and more. Challenge yourself and see how much you know about this fascinating subject.
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