Principles of Antimicrobial Therapy

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Questions and Answers

What is the primary factor in determining the time of initiation of therapy in antimicrobial treatment?

  • Severity of infection (correct)
  • Drug factors
  • Patient factors
  • Microbial factors

Which of the following is an example of a patient factor to consider when selecting an antimicrobial drug?

  • Gram-positive or negative spectrum of the drug
  • Cost of the drug
  • Renal function of the patient (correct)
  • Lipid solubility of the drug

What is the primary reason why cost is an important consideration in selecting an antimicrobial drug?

  • It affects the adverse effects profile of the drug
  • It affects the frequency of administration
  • It affects the spectrum of the drug
  • It is a significant factor in patient adherence (correct)

Which of the following is an example of a microbial factor to consider when selecting an antimicrobial drug?

<p>Identification of the infecting organism (A)</p> Signup and view all the answers

What is the significance of BBB penetration in antimicrobial treatment?

<p>It affects the ability of the drug to penetrate the CNS (C)</p> Signup and view all the answers

Which of the following is an example of a drug factor to consider when selecting an antimicrobial drug?

<p>Adverse effects profile of the drug (C)</p> Signup and view all the answers

What is the primary classification system based on the effect of antibacterial agents on bacterial growth?

<p>Effect on bacterial growth (C)</p> Signup and view all the answers

Which type of antibacterial agents acts mainly against Gram positive bacteria?

<p>Penicillins (C)</p> Signup and view all the answers

What is the term for antibacterial agents that kill bacteria?

<p>Bactericidal (D)</p> Signup and view all the answers

Which of the following antibacterial agents is primarily bacteriostatic, but can be bactericidal against certain species?

<p>Chloramphenicol (D)</p> Signup and view all the answers

What is the term for antibacterial agents that are effective against both Gram positive and Gram negative bacteria?

<p>Broad spectrum (C)</p> Signup and view all the answers

Which of the following antibacterial agents is an example of a concentration-dependant agent?

<p>Quinolone (C)</p> Signup and view all the answers

What is the broadened definition of chemotherapy?

<p>Therapeutic use of chemical substances that selectively act on microbes or cancers (A)</p> Signup and view all the answers

What is the primary purpose of antimicrobial therapy?

<p>To destroy or suppress the growth of other microorganisms (D)</p> Signup and view all the answers

What is included in the classification of antimicrobials?

<p>Antibacterials, antivirals, antifungals, and antiprotozoals (C)</p> Signup and view all the answers

What is the first step in choosing the suitable antimicrobial?

<p>Diagnose whether it is an infection or not (C)</p> Signup and view all the answers

What is the definition of rational use of antimicrobials?

<p>Right drug, Right dose, Right route, Right duration, for Right pt.with minimal side effects (B)</p> Signup and view all the answers

What is the primary goal of rational use of antimicrobials?

<p>To cure the infection with minimal side effects (A)</p> Signup and view all the answers

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