Podcast
Questions and Answers
What is the typical size range of aldosterone-producing adenomas?
What is the typical size range of aldosterone-producing adenomas?
- 1-32 mm in diameter (correct)
- 5-10 mm in diameter
- 10-50 mm in diameter
- 1-5 mm in diameter
What type of cells are typically found in aldosterone-producing adenomas?
What type of cells are typically found in aldosterone-producing adenomas?
- Lipid-poor, zona glomerulosa-like cells
- Compact, basophilic cells
- Compact, eosinophilic cells
- Lipid-rich, zona fasciculata-like cells (correct)
What is the underlying cause of secondary hyperaldosteronism?
What is the underlying cause of secondary hyperaldosteronism?
- Mutation in the mineralocorticoid receptor gene
- Excess aldosterone production by the adrenal gland
- Activation of the renin-angiotensin system due to an extra-adrenal cause (correct)
- Adrenal cortical adenoma
What is a rare cause of secondary hyperaldosteronism?
What is a rare cause of secondary hyperaldosteronism?
What is a complication of hyperaldosteronism?
What is a complication of hyperaldosteronism?
What is the effect of hyperaldosteronism on sodium levels?
What is the effect of hyperaldosteronism on sodium levels?
What is the effect of hyperaldosteronism on blood pressure?
What is the effect of hyperaldosteronism on blood pressure?
What is the effect of hyperaldosteronism on metabolic balance?
What is the effect of hyperaldosteronism on metabolic balance?
What percentage of Primary Aldosteronism cases are attributed to Bilateral Idiopathic Hyperaldosteronism?
What percentage of Primary Aldosteronism cases are attributed to Bilateral Idiopathic Hyperaldosteronism?
Which of the following mutations is associated with Aldosterone-producing Adrenal Cortical Adenoma?
Which of the following mutations is associated with Aldosterone-producing Adrenal Cortical Adenoma?
What is the percentage of Familial Hyperaldosteronism in Primary Aldosteronism cases?
What is the percentage of Familial Hyperaldosteronism in Primary Aldosteronism cases?
What is the result of the activation of aldosterone synthase in Aldosterone-producing Adrenal Cortical Adenoma?
What is the result of the activation of aldosterone synthase in Aldosterone-producing Adrenal Cortical Adenoma?
What is the function of Mineralocorticoid Receptor in the context of Primary Aldosteronism?
What is the function of Mineralocorticoid Receptor in the context of Primary Aldosteronism?
What is the percentage of ATP1A1 mutations associated with Aldosterone-producing Adrenal Cortical Adenoma?
What is the percentage of ATP1A1 mutations associated with Aldosterone-producing Adrenal Cortical Adenoma?
What is the primary cause of Hyperaldosteronism in Primary Aldosteronism?
What is the primary cause of Hyperaldosteronism in Primary Aldosteronism?
What is the result of Mineralocorticoid Excess in the context of Primary Aldosteronism?
What is the result of Mineralocorticoid Excess in the context of Primary Aldosteronism?
What is the primary function of aldosterone in the adrenal gland?
What is the primary function of aldosterone in the adrenal gland?
Which of the following is a characteristic of aldosterone-producing adrenal cortical adenoma?
Which of the following is a characteristic of aldosterone-producing adrenal cortical adenoma?
What is the percentage of bilateral idiopathic hyperaldosteronism in primary hyperaldosteronism cases?
What is the percentage of bilateral idiopathic hyperaldosteronism in primary hyperaldosteronism cases?
What is the rare genetic condition that causes familial hyperaldosteronism?
What is the rare genetic condition that causes familial hyperaldosteronism?
What is the primary mechanism of action of aldosterone in the kidneys?
What is the primary mechanism of action of aldosterone in the kidneys?
Which of the following is a characteristic of primary hyperaldosteronism?
Which of the following is a characteristic of primary hyperaldosteronism?
What is the layer of the adrenal cortex responsible for producing aldosterone?
What is the layer of the adrenal cortex responsible for producing aldosterone?
Which of the following is a complication of primary hyperaldosteronism?
Which of the following is a complication of primary hyperaldosteronism?
What is the primary goal of treatment in patients with aldosterone-producing adrenal cortical adenoma?
What is the primary goal of treatment in patients with aldosterone-producing adrenal cortical adenoma?
What is the effect of bilateral idiopathic hyperaldosteronism on adrenal function?
What is the effect of bilateral idiopathic hyperaldosteronism on adrenal function?
What is the main function of the mineralocorticoid receptor?
What is the main function of the mineralocorticoid receptor?
What is the primary difference between primary hyperaldosteronism and secondary hyperaldosteronism?
What is the primary difference between primary hyperaldosteronism and secondary hyperaldosteronism?
What is the purpose of the saline suppression test in the diagnosis of primary hyperaldosteronism?
What is the purpose of the saline suppression test in the diagnosis of primary hyperaldosteronism?
What is the common feature of familial hyperaldosteronism and primary hyperaldosteronism?
What is the common feature of familial hyperaldosteronism and primary hyperaldosteronism?
What is the medication of choice for the treatment of bilateral idiopathic hyperaldosteronism?
What is the medication of choice for the treatment of bilateral idiopathic hyperaldosteronism?
What is the effect of aldosterone on potassium levels?
What is the effect of aldosterone on potassium levels?
What is the primary purpose of measuring cortisol levels in diagnosing Cushing's syndrome?
What is the primary purpose of measuring cortisol levels in diagnosing Cushing's syndrome?
What is the expected result of a dexamethasone suppression test in a patient with a pituitary microadenoma?
What is the expected result of a dexamethasone suppression test in a patient with a pituitary microadenoma?
What is the primary treatment approach for pituitary microadenoma in Cushing's syndrome?
What is the primary treatment approach for pituitary microadenoma in Cushing's syndrome?
What is the potential complication of suddenly stopping exogenous medications in Cushing's syndrome?
What is the potential complication of suddenly stopping exogenous medications in Cushing's syndrome?
What is the role of ketoconazole and metyrapone in the treatment of Cushing's syndrome?
What is the role of ketoconazole and metyrapone in the treatment of Cushing's syndrome?
What is the purpose of imaging studies in the diagnosis of Cushing's syndrome?
What is the purpose of imaging studies in the diagnosis of Cushing's syndrome?
What is the expected result of measuring ACTH levels in a patient with adrenal neoplasms?
What is the expected result of measuring ACTH levels in a patient with adrenal neoplasms?
What is the primary goal of treatment in Cushing's syndrome?
What is the primary goal of treatment in Cushing's syndrome?
