1- Measures of frequency

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Questions and Answers

What does prevalence measure in a population?

  • The total number of people in the population
  • The number of people with a disease at a specific time (correct)
  • The specific cause of the disease
  • The burden of disease in a population

Why is prevalence NOT useful for determining what caused a disease?

  • Prevalence only tells us how many are affected but not why or how (correct)
  • Prevalence is directly linked to the total population size
  • Prevalence focuses on specific events like birth and death
  • Prevalence is calculated at a specific point in time

What is point prevalence?

  • The lifetime risk of having a certain disease
  • The proportion of persons with a particular disease on a specific date/time (correct)
  • The proportion of events like birth and death in a population
  • The total number of people in the population at any given time

Which of the following is a characteristic of period prevalence?

<p>is the proportion of a population that has the disease during a given time period of interest (B)</p> Signup and view all the answers

What information does prevalence provide for planning health services?

<p>Burden of diseases in a population (B)</p> Signup and view all the answers

Which group should be excluded from the denominator when calculating incidence?

<p>People who already have the disease and People who are immune to the disease (D)</p> Signup and view all the answers

What is the key focus when assessing incidence in a population?

<p>Measuring the probability of developing the disease over time (A)</p> Signup and view all the answers

Why are individuals with immunity or those who lack susceptibility not included in incidence calculations?

<p>To avoid underestimating the risk in the population (D)</p> Signup and view all the answers

What distinguishes Incidence Rate from Cumulative Risk in measuring new disease cases?

<p>How they account for different time periods (C)</p> Signup and view all the answers

Why is Cumulative Risk not valid when a large number of people leave your study?

<p>It distorts the actual incidence proportion (A)</p> Signup and view all the answers

What is the main issue with loss to follow-up in a study?

<p>Different dropout rates between study groups (C)</p> Signup and view all the answers

In which scenario is risk a more valid measure of disease frequency?

<p>When the follow-up period is short and loss to follow-up is low (A)</p> Signup and view all the answers

What is the incidence rate?

<p>The rate at which people come down with a disease (D)</p> Signup and view all the answers

How is incidence rate calculated?

<p>Number of cases divided by the total person-time at risk (D)</p> Signup and view all the answers

What does incidence rate help address in studies where incidence proportion may be limited?

<p>Both A and c (D)</p> Signup and view all the answers

When is risk considered less valid as a measure of disease frequency?

<p>With longer follow-up periods and high loss to follow-up (A)</p> Signup and view all the answers

What is the concept behind person-time in calculating incidence rates?

<p>The total amount of time each person spends in the study (C)</p> Signup and view all the answers

In practice, why do different people contribute different amounts of person-time in calculating incidence rates?

<p>As a result of different times they are enrolled and develop the disease (C)</p> Signup and view all the answers

What does the incidence rate measure?

<p>The rate at which new cases occur per unit of person-time (B)</p> Signup and view all the answers

What does hazard rate refer to in epidemiology?

<p>The likelihood of developing a disease after exposure to a risk factor (D)</p> Signup and view all the answers

Why are individuals who have already contracted the illness often not considered at risk for developing it again in incidence calculations?

<p>To avoid counting them multiple times and inflating incidence rates (C)</p> Signup and view all the answers

What is a key difference between Cumulative Risk (CR) and Incidence Rate (IR) in measuring new disease cases?

<p>CR is easier to calculate, while IR is more accurate. (E)</p> Signup and view all the answers

When comparing Cumulative Risk (CR) and Incidence Rate (IR), which statement is true?

<p>CR is more useful for fixed populations, while IR is more useful for dynamic populations. (C)</p> Signup and view all the answers

Which of the following accurately describes the calculation of Incidence Rate (IR)?

<p>It involves a complex person-time denominator calculation to determine new cases. (E)</p> Signup and view all the answers

When considering the distinction between Cumulative Risk (CR) and Incidence Rate (IR), which characteristic makes CR less accurate?

<p>It becomes less accurate when its assumptions are not met. (E)</p> Signup and view all the answers

What does Mortality Rate measure?

<p>Number of deaths divided by the total population during a specified time period (B)</p> Signup and view all the answers

Which of the following defines Morbidity Rate?

<p>Incidence of non-fatal cases of a disease in a population during a specified time period (C)</p> Signup and view all the answers

Which term refers to the proportion of those exposed that develop the disease?

<p>Attack Rate (D)</p> Signup and view all the answers

What characterizes the concept of causation in relation to a disease?

<p>An event, condition, or characteristic that precedes the disease and is necessary for its occurrence (A)</p> Signup and view all the answers

When considering the concept of causation in epidemiology, what does it mean when we say cause is viewed probabilistically?

<p>Everyone exposed has a higher risk of developing the disease (A)</p> Signup and view all the answers

Which of the following is NOT one of Hill’s criteria for establishing causality?

<p>Mortality rate measurement (B)</p> Signup and view all the answers

Why is it important for exposure to precede the disease when considering temporality in epidemiology?

<p>To establish a causal relationship between exposure and disease (C)</p> Signup and view all the answers

Which of the following is NOT a component of Hill’s criteria for establishing causality?

<p>Temporal consistency (C)</p> Signup and view all the answers

What is the significance of a stronger association in epidemiology?

<p>It suggests a causal relationship (A)</p> Signup and view all the answers

In epidemiology, what does the dose-response relationship suggest?

<p>Higher exposure amounts are linked to higher disease risk (A)</p> Signup and view all the answers

Why is replicating findings in multiple studies important in epidemiology?

<p>To demonstrate consistency and increase the likelihood of causality (A)</p> Signup and view all the answers

What role does biologic plausibility play in epidemiological studies?

<p>It ensures that proposed mechanisms align with current biological knowledge (A)</p> Signup and view all the answers

How does the strength of association relate to the explanation of weaker associations?

<p>They are typically explained by bias or confounding (B)</p> Signup and view all the answers

What does a measure of association quantify in epidemiology?

<p>The relationship between exposure and disease (D)</p> Signup and view all the answers

Which scale tells us the relative increase or decrease in effect comparing one quantity to another?

<p>Relative scale (C)</p> Signup and view all the answers

Which measure is not commonly used in epidemiology but is important to understand conceptually?

<p>Prevalence ratio (D)</p> Signup and view all the answers

What does Prevalence Ratio calculate for each exposure group?

<p>Prevalence (B)</p> Signup and view all the answers

Which measure tells us the absolute increase or decrease in effect?

<p>Absolute scale (B)</p> Signup and view all the answers

What does the Risk Ratio (RR) measure?

<p>Disease risk in exposed and unexposed groups (A)</p> Signup and view all the answers

What does the Incidence Rate Ratio (IRR) compare?

<p>Risk of disease in exposed vs unexposed groups (A)</p> Signup and view all the answers

What is the range of values for the Risk Ratio (RR)?

<p>0 to +∞ (C)</p> Signup and view all the answers

How are populations divided when calculating Risk Ratio (RR)?

<p>Exposed and unexposed to a particular factor (B)</p> Signup and view all the answers

What is the key characteristic of the Incidence Rate Ratio (IRR)?

<p>It compares the incidence rates for two groups (C)</p> Signup and view all the answers

What is the key difference between Risk Difference (RD) and Incidence Rate Difference (IRD)?

<p>RD refers to the additional risk among those exposed, while IRD refers to the difference in incidence rates (D)</p> Signup and view all the answers

Which measure of association has a range from -∞ to +∞?

<p>Incidence Rate Difference (IRD) (C)</p> Signup and view all the answers

Why is it not possible to calculate rate and prevalence measures from the given 2x2 table data?

<p>No person-time information available (C)</p> Signup and view all the answers

What does the Incidence Rate Difference (IRD) measure?

<p>Additional risk among those exposed compared to those unexposed (A)</p> Signup and view all the answers

What does the Absolute Scale Risk Difference (RD) quantify?

<p>Additional risk among those exposed compared to those unexposed (D)</p> Signup and view all the answers

What does a Relative Risk (RR) of 1 indicate?

<p>There is no effect or association between exposure and disease (D)</p> Signup and view all the answers

If the Risk Difference (RD) is 0, what does it imply?

<p>There is no effect or association between exposure and disease (D)</p> Signup and view all the answers

When the Odds Ratio (OR) is greater than 1, what does it suggest?

<p>There is a higher risk in the exposed group (D)</p> Signup and view all the answers

If the Incidence Rate Difference (IRD) is negative, what does it indicate?

<p>There is a decrease in disease incidence among the exposed (D)</p> Signup and view all the answers

What conclusion can be drawn when the Relative Risk (RR) is less than 1?

<p>There is a lower risk in the exposed group (C)</p> Signup and view all the answers

What does the Risk Ratio provide information on?

<p>Strength of association (C)</p> Signup and view all the answers

How does the Risk Difference differ from the Risk Ratio?

<p>One measures strength of association, the other measures public health impact (B)</p> Signup and view all the answers

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