Prescription Medications for Constipation

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Which statement about stimulant purgatives is true?

They have no effect on enteric nerves or colonic motility.
They promote the release of water and electrolytes into the colon, reducing stool surface area. (correct)
They are recommended for use during pregnancy due to their safety.
They are safe for long-term use without any potential side effects.

Which purgative is particularly effective in opioid-related constipation?

Bisacodyl
Ispaghula husk
Senna (correct)
Methylcellulose

Why should sennosides be avoided during pregnancy?

They have shown mutagenic effects in rodents due to systemic retention. (correct)
They are less effective in treating constipation during pregnancy.
They are not systemically absorbed.
They can cause bloating and diarrhea.

What is the preferred choice for treating constipation due to its safety and taste?

Bulk-forming agents (D) Signup and view all the answers

Which bulk-forming agent is considered safe for long-term preventative therapy?

Polycarbophil (D) Signup and view all the answers

Which of the following statements about bulk-forming agents is true?

They should be gradually increased in dosage to prevent bloating and diarrhea. (B) Signup and view all the answers

Which statement about bulking agents is true?

Bulking agents increase faecal mass and soften faeces by retaining water and enhancing intestinal motility. (B) Signup and view all the answers

What is the main cause of constipation according to the text?

Slow transit of fecal matter through the colon, resulting in hard, dry, and difficult-to-pass stools. (B) Signup and view all the answers

Which statement about stimulant laxatives is correct?

They are effective in opioid-induced constipation as they increase the motility of the small intestine and colon. (C) Signup and view all the answers

What is the purpose of lubricant laxatives like mineral oil?

To soften feces and facilitate stool passage. (B) Signup and view all the answers

Which of the following is a potential adverse effect of high dose magnesium salts used as saline laxatives?

Severe adverse effects, especially in renal impairment. (B) Signup and view all the answers

Which of the following statements about Micralax is true?

It is a combined soft soap and rectal laxative that is fast-acting and softens stool. (A) Signup and view all the answers

Which of the following statements about mineral oil is incorrect?

It should be taken in the morning for effective defecation. (D) Signup and view all the answers

Which of the following is true about saline laxatives?

They are non-absorbable substances that draw water into the gut lumen, providing mechanical relief for fecal evacuation. (C) Signup and view all the answers