Prescribing Empiric Therapy: Step-by-Step Guide
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Questions and Answers

What is the main reason behind the efficacy of once-daily dosing regimens?

  • Post antibiotic effect (correct)
  • Risk of drug toxicity
  • Increased cost
  • Risk of superinfection

    • What does synergism refer to in the context of antimicrobial drug combinations?

  • Enhanced inhibition or killing by combining drugs (correct)
  • Increased microbial resistance
  • Decreased toxicity
  • Decreased drug uptake

    • Which of the following is NOT an advantage of using antimicrobial drug combinations?

  • Reduced dose-related toxicity
  • Increased cost (correct)
  • Broad-spectrum empiric therapy
  • Decreased emergence of resistant strains

    • What is the primary disadvantage associated with combination therapy using antimicrobial drugs?

    <p>Risk of superinfection</p> Signup and view all the answers

    What effect does synergy have on the Minimum Inhibitory Concentration (MIC) or Minimum Bactericidal Concentration (MBC) of each drug when used in combination?

    <p>Decrease in MIC or MBC</p> Signup and view all the answers

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