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Questions and Answers
What is the main reason behind the efficacy of once-daily dosing regimens?
What is the main reason behind the efficacy of once-daily dosing regimens?
- Post antibiotic effect (correct)
- Risk of drug toxicity
- Increased cost
- Risk of superinfection
What does synergism refer to in the context of antimicrobial drug combinations?
What does synergism refer to in the context of antimicrobial drug combinations?
- Enhanced inhibition or killing by combining drugs (correct)
- Increased microbial resistance
- Decreased toxicity
- Decreased drug uptake
Which of the following is NOT an advantage of using antimicrobial drug combinations?
Which of the following is NOT an advantage of using antimicrobial drug combinations?
- Reduced dose-related toxicity
- Increased cost (correct)
- Broad-spectrum empiric therapy
- Decreased emergence of resistant strains
What is the primary disadvantage associated with combination therapy using antimicrobial drugs?
What is the primary disadvantage associated with combination therapy using antimicrobial drugs?
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What effect does synergy have on the Minimum Inhibitory Concentration (MIC) or Minimum Bactericidal Concentration (MBC) of each drug when used in combination?
What effect does synergy have on the Minimum Inhibitory Concentration (MIC) or Minimum Bactericidal Concentration (MBC) of each drug when used in combination?
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