Podcast
Questions and Answers
What is the term for chromosomes that are classifed based on the position of the centromere?
What is the term for chromosomes that are classifed based on the position of the centromere?
- Acrocentric
- Telomeric
- Submetacentric
- Metacentric (correct)
Which enzyme maintains chromosome integrity by replacing the 5′ end of the long strand during DNA replication?
Which enzyme maintains chromosome integrity by replacing the 5′ end of the long strand during DNA replication?
- Ligase
- Helicase
- Telomerase (correct)
- DNA polymerase
How many divisions can most cells undergo before becoming senescent due to a critical length of chromosomes?
How many divisions can most cells undergo before becoming senescent due to a critical length of chromosomes?
- 50 to 60 divisions (correct)
- 40 to 50 divisions
- 20 to 30 divisions
- 70 to 80 divisions
What is the diploid number of chromosomes in humans?
What is the diploid number of chromosomes in humans?
Which organism has 54 chromosomes?
Which organism has 54 chromosomes?
What type of chromosome has the centromere located at an intermediate position?
What type of chromosome has the centromere located at an intermediate position?
What parameters were used by early pioneers of cytogenetics to classify individual chromosomes?
What parameters were used by early pioneers of cytogenetics to classify individual chromosomes?
In which condition might a man with Klinefelter's disease go undiagnosed until puberty or adulthood?
In which condition might a man with Klinefelter's disease go undiagnosed until puberty or adulthood?
What labels were used to subdivide chromosomes into groups based on overall morphology?
What labels were used to subdivide chromosomes into groups based on overall morphology?
When might a genetic karyotype be done for infertility?
When might a genetic karyotype be done for infertility?
In what scenario might a woman with Turner syndrome or a man with Klinefelter's be unaware of their condition?
In what scenario might a woman with Turner syndrome or a man with Klinefelter's be unaware of their condition?
Why might infants or children with certain medical conditions need karyotyping?
Why might infants or children with certain medical conditions need karyotyping?
What is the estimated frequency of triploidy in live births?
What is the estimated frequency of triploidy in live births?
Why might parents undergo testing if a child is born with translocation Down syndrome?
Why might parents undergo testing if a child is born with translocation Down syndrome?
What percentage of miscarriages are thought to be caused by chromosomal abnormalities like trisomy 16?
What percentage of miscarriages are thought to be caused by chromosomal abnormalities like trisomy 16?
What type of leukemia may be diagnosed by looking for the Philadelphia chromosome?
What type of leukemia may be diagnosed by looking for the Philadelphia chromosome?
What is the main reason for conducting karyotype testing following a stillbirth?
What is the main reason for conducting karyotype testing following a stillbirth?
What is the term used for cells that have more than two sets of chromosomes?
What is the term used for cells that have more than two sets of chromosomes?
What is the most common cause of intellectual disability?
What is the most common cause of intellectual disability?
Which chromosomal disorder has the widest phenotypic variation affecting almost every organ?
Which chromosomal disorder has the widest phenotypic variation affecting almost every organ?
In which type of meiosis does about 75% of maternal nondisjunctions leading to Trisomy 21 occur?
In which type of meiosis does about 75% of maternal nondisjunctions leading to Trisomy 21 occur?
What is the most common trisomy among the ones mentioned in the text?
What is the most common trisomy among the ones mentioned in the text?
What is the primary cause of Trisomy 21 (Down Syndrome)?
What is the primary cause of Trisomy 21 (Down Syndrome)?
Which trisomy has a survival rate of less than 3 days after birth?
Which trisomy has a survival rate of less than 3 days after birth?
What is the main characteristic feature of Trisomy 21 on examination?
What is the main characteristic feature of Trisomy 21 on examination?
Which syndrome is characterized by short stature, sexual infantilism, and webbed neck?
Which syndrome is characterized by short stature, sexual infantilism, and webbed neck?
What percentage of Trisomy 21 cases have the extra chromosome contributed by the mother?
What percentage of Trisomy 21 cases have the extra chromosome contributed by the mother?
What is a common feature of Trisomy X syndrome?
What is a common feature of Trisomy X syndrome?
Which syndrome results in a mild phenotype in comparison with the other syndromes mentioned?
Which syndrome results in a mild phenotype in comparison with the other syndromes mentioned?
What is a common consequence of Translocations?
What is a common consequence of Translocations?
Flashcards are hidden until you start studying
