Podcast
Questions and Answers
Preformulation study Is the application of biopharmaceutical principles on physicochemical parameters of drug to design an ideal drug delivery system. Preformulation programs must consider the following factors 1. The amount of drug available 2. The physicochemical properties of the drug. 3. Therapeutic category and anticipated dose of compound. 4. The nature of information, a formulation should have or would like to have. Special studies are conducted depending on the type of dosage form and the type of drug molecules 1) Solubility determination. 2) pKa determination. 3) Partition coefficient. 4) Crystal form and polymorphism. 5) Particle size, shape and surface area. 6) Chemical stability profile. Solubility analysis solubility drug release bioavailability the therapeutic efficiency Solubility analysis Solubility determined in different solvents and some oils if the drug is lipophilic The solubility determined by equilibrium solubility method , which employs a saturated solution of the material, obtained by stirring an excess of material in the solvent for a prolonged time until equilibrium is achieved. pKa determinations Determination of pKa for a drug capable of ionization within a pH rang of 1 to 10 is important.
Preformulation study Is the application of biopharmaceutical principles on physicochemical parameters of drug to design an ideal drug delivery system. Preformulation programs must consider the following factors 1. The amount of drug available 2. The physicochemical properties of the drug. 3. Therapeutic category and anticipated dose of compound. 4. The nature of information, a formulation should have or would like to have. Special studies are conducted depending on the type of dosage form and the type of drug molecules 1) Solubility determination. 2) pKa determination. 3) Partition coefficient. 4) Crystal form and polymorphism. 5) Particle size, shape and surface area. 6) Chemical stability profile. Solubility analysis solubility drug release bioavailability the therapeutic efficiency Solubility analysis Solubility determined in different solvents and some oils if the drug is lipophilic The solubility determined by equilibrium solubility method , which employs a saturated solution of the material, obtained by stirring an excess of material in the solvent for a prolonged time until equilibrium is achieved. pKa determinations Determination of pKa for a drug capable of ionization within a pH rang of 1 to 10 is important.
Preformulation study Is the application of biopharmaceutical principles on physicochemical parameters of drug to design an ideal drug delivery system. Preformulation programs must consider the following factors 1. The amount of drug available 2. The physicochemical properties of the drug. 3. Therapeutic category and anticipated dose of compound. 4. The nature of information, a formulation should have or would like to have. Special studies are conducted depending on the type of dosage form and the type of drug molecules 1) Solubility determination. 2) pKa determination. 3) Partition coefficient. 4) Crystal form and polymorphism. 5) Particle size, shape and surface area. 6) Chemical stability profile. Solubility analysis solubility drug release bioavailability the therapeutic efficiency Solubility analysis Solubility determined in different solvents and some oils if the drug is lipophilic The solubility determined by equilibrium solubility method , which employs a saturated solution of the material, obtained by stirring an excess of material in the solvent for a prolonged time until equilibrium is achieved. pKa determinations Determination of pKa for a drug capable of ionization within a pH rang of 1 to 10 is important.
Preformulation study Is the application of biopharmaceutical principles on physicochemical parameters of drug to design an ideal drug delivery system. Preformulation programs must consider the following factors 1. The amount of drug available 2. The physicochemical properties of the drug. 3. Therapeutic category and anticipated dose of compound. 4. The nature of information, a formulation should have or would like to have. Special studies are conducted depending on the type of dosage form and the type of drug molecules 1) Solubility determination. 2) pKa determination. 3) Partition coefficient. 4) Crystal form and polymorphism. 5) Particle size, shape and surface area. 6) Chemical stability profile. Solubility analysis solubility drug release bioavailability the therapeutic efficiency Solubility analysis Solubility determined in different solvents and some oils if the drug is lipophilic The solubility determined by equilibrium solubility method , which employs a saturated solution of the material, obtained by stirring an excess of material in the solvent for a prolonged time until equilibrium is achieved. pKa determinations Determination of pKa for a drug capable of ionization within a pH rang of 1 to 10 is important.
Preformulation study Is the application of biopharmaceutical principles on physicochemical parameters of drug to design an ideal drug delivery system. Preformulation programs must consider the following factors 1. The amount of drug available 2. The physicochemical properties of the drug. 3. Therapeutic category and anticipated dose of compound. 4. The nature of information, a formulation should have or would like to have. Special studies are conducted depending on the type of dosage form and the type of drug molecules 1) Solubility determination. 2) pKa determination. 3) Partition coefficient. 4) Crystal form and polymorphism. 5) Particle size, shape and surface area. 6) Chemical stability profile. Solubility analysis solubility drug release bioavailability the therapeutic efficiency Solubility analysis Solubility determined in different solvents and some oils if the drug is lipophilic The solubility determined by equilibrium solubility method , which employs a saturated solution of the material, obtained by stirring an excess of material in the solvent for a prolonged time until equilibrium is achieved. pKa determinations Determination of pKa for a drug capable of ionization within a pH rang of 1 to 10 is important.
Preformulation study Is the application of biopharmaceutical principles on physicochemical parameters of drug to design an ideal drug delivery system. Preformulation programs must consider the following factors 1. The amount of drug available 2. The physicochemical properties of the drug. 3. Therapeutic category and anticipated dose of compound. 4. The nature of information, a formulation should have or would like to have. Special studies are conducted depending on the type of dosage form and the type of drug molecules 1) Solubility determination. 2) pKa determination. 3) Partition coefficient. 4) Crystal form and polymorphism. 5) Particle size, shape and surface area. 6) Chemical stability profile. Solubility analysis solubility drug release bioavailability the therapeutic efficiency Solubility analysis Solubility determined in different solvents and some oils if the drug is lipophilic The solubility determined by equilibrium solubility method , which employs a saturated solution of the material, obtained by stirring an excess of material in the solvent for a prolonged time until equilibrium is achieved. pKa determinations Determination of pKa for a drug capable of ionization within a pH rang of 1 to 10 is important.
Preformulation study Is the application of biopharmaceutical principles on physicochemical parameters of drug to design an ideal drug delivery system. Preformulation programs must consider the following factors 1. The amount of drug available 2. The physicochemical properties of the drug. 3. Therapeutic category and anticipated dose of compound. 4. The nature of information, a formulation should have or would like to have. Special studies are conducted depending on the type of dosage form and the type of drug molecules 1) Solubility determination. 2) pKa determination. 3) Partition coefficient. 4) Crystal form and polymorphism. 5) Particle size, shape and surface area. 6) Chemical stability profile. Solubility analysis solubility drug release bioavailability the therapeutic efficiency Solubility analysis Solubility determined in different solvents and some oils if the drug is lipophilic The solubility determined by equilibrium solubility method , which employs a saturated solution of the material, obtained by stirring an excess of material in the solvent for a prolonged time until equilibrium is achieved. pKa determinations Determination of pKa for a drug capable of ionization within a pH rang of 1 to 10 is important.
Preformulation study Is the application of biopharmaceutical principles on physicochemical parameters of drug to design an ideal drug delivery system. Preformulation programs must consider the following factors 1. The amount of drug available 2. The physicochemical properties of the drug. 3. Therapeutic category and anticipated dose of compound. 4. The nature of information, a formulation should have or would like to have. Special studies are conducted depending on the type of dosage form and the type of drug molecules 1) Solubility determination. 2) pKa determination. 3) Partition coefficient. 4) Crystal form and polymorphism. 5) Particle size, shape and surface area. 6) Chemical stability profile. Solubility analysis solubility drug release bioavailability the therapeutic efficiency Solubility analysis Solubility determined in different solvents and some oils if the drug is lipophilic The solubility determined by equilibrium solubility method , which employs a saturated solution of the material, obtained by stirring an excess of material in the solvent for a prolonged time until equilibrium is achieved. pKa determinations Determination of pKa for a drug capable of ionization within a pH rang of 1 to 10 is important.
Signup and view all the answers
Preformulation study Is the application of biopharmaceutical principles on physicochemical parameters of drug to design an ideal drug delivery system. Preformulation programs must consider the following factors 1. The amount of drug available 2. The physicochemical properties of the drug. 3. Therapeutic category and anticipated dose of compound. 4. The nature of information, a formulation should have or would like to have. Special studies are conducted depending on the type of dosage form and the type of drug molecules 1) Solubility determination. 2) pKa determination. 3) Partition coefficient. 4) Crystal form and polymorphism. 5) Particle size, shape and surface area. 6) Chemical stability profile. Solubility analysis solubility drug release bioavailability the therapeutic efficiency Solubility analysis Solubility determined in different solvents and some oils if the drug is lipophilic The solubility determined by equilibrium solubility method , which employs a saturated solution of the material, obtained by stirring an excess of material in the solvent for a prolonged time until equilibrium is achieved. pKa determinations Determination of pKa for a drug capable of ionization within a pH rang of 1 to 10 is important.
Preformulation study Is the application of biopharmaceutical principles on physicochemical parameters of drug to design an ideal drug delivery system. Preformulation programs must consider the following factors 1. The amount of drug available 2. The physicochemical properties of the drug. 3. Therapeutic category and anticipated dose of compound. 4. The nature of information, a formulation should have or would like to have. Special studies are conducted depending on the type of dosage form and the type of drug molecules 1) Solubility determination. 2) pKa determination. 3) Partition coefficient. 4) Crystal form and polymorphism. 5) Particle size, shape and surface area. 6) Chemical stability profile. Solubility analysis solubility drug release bioavailability the therapeutic efficiency Solubility analysis Solubility determined in different solvents and some oils if the drug is lipophilic The solubility determined by equilibrium solubility method , which employs a saturated solution of the material, obtained by stirring an excess of material in the solvent for a prolonged time until equilibrium is achieved. pKa determinations Determination of pKa for a drug capable of ionization within a pH rang of 1 to 10 is important.
Signup and view all the answers
